KEGG ORTHOLOGY: K07886

ORTHOLOGY: K07886

Entry

K07886                      KO

Symbol

RAB27B

Name

Ras-related protein Rab-27B

Pathway

map04972

Pancreatic secretion

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09154 Digestive system
   04972 Pancreatic secretion
    K07886  RAB27B; Ras-related protein Rab-27B
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K07886  RAB27B; Ras-related protein Rab-27B
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K07886  RAB27B; Ras-related protein Rab-27B
   04031 GTP-binding proteins
    K07886  RAB27B; Ras-related protein Rab-27B
Membrane trafficking [BR:ko04131]
Exocytosis
  Small GTPases and associated proteins
   Rab GTPases
    K07886  RAB27B; Ras-related protein Rab-27B
Exosome [BR:ko04147]
Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K07886  RAB27B; Ras-related protein Rab-27B
GTP-binding proteins [BR:ko04031]
Small (monomeric) G-proteins
  Rab Family
   Rab3/27 [OT]
    K07886  RAB27B; Ras-related protein Rab-27B

Genes

HSA:	5874(RAB27B)

PTR:	468542(RAB27B)

PPS:	100995239(RAB27B)

GGO:	101134113(RAB27B)

PON:	100444913(RAB27B)

NLE:	100583827(RAB27B)

HMH:	116468527(RAB27B)

MCC:	694445(RAB27B)

MCF:	102118542(RAB27B)

MTHB:

126941371

MNI:	105477108(RAB27B)

CSAB:

103244241(RAB27B)

CATY:

105589947(RAB27B)

PANU:

100997329(RAB27B)

TGE:	112611433(RAB27B)

MLEU:

105533314(RAB27B)

RRO:	104672195(RAB27B)

RBB:	108514099(RAB27B)

TFN:	117098988(RAB27B)

PTEH:

111546872(RAB27B)

CANG:

105516762(RAB27B)

CJC:	100395885(RAB27B)

SBQ:	101028160(RAB27B)

CIMI:

108282190(RAB27B)

CSYR:

103257147(RAB27B)

MMUR:

105860614(RAB27B)

LCAT:

123621747(RAB27B)

PCOQ:

105816357(RAB27B)

OGA:	100963087(RAB27B)

MMU:	80718(Rab27b)

MCAL:

110284927(Rab27b)

MPAH:

110333246(Rab27b)

RNO:	84590(Rab27b)

MCOC:

116087320(Rab27b)

ANU:	117719888(Rab27b)

MUN:	110564104(Rab27b)

CGE:	100761592(Rab27b)

MAUA:

101822849(Rab27b)

PROB:

127234184(Rab27b)

PLEU:

114690175(Rab27b)

MORG:

121438819(Rab27b)

MFOT:

126488314

AAMP:

119814122(Rab27b)

NGI:	103736203(Rab27b)

HGL:	101705828(Rab27b)

CPOC:

100732593(Rab27b)

CCAN:

109688455(Rab27b)

DORD:

105987615(Rab27b)

DSP:	122104314(Rab27b)

PLOP:

125364131(Rab27b)

NCAR:

124965486

MMMA:

107139381(Rab27b)

OCU:

100343056

OPI:	101524853(RAB27B)

TUP:	102472052(RAB27B)

GVR:	103609255(RAB27B)

CFA:	483974(RAB27B)

CLUD:

112644086(RAB27B)

VVP:	112919279(RAB27B)

VLG:	121482080(RAB27B)

NPO:	129495529 129514575

AML:	100465563(RAB27B)

UMR:	103664468(RAB27B)

UAH:	113253438(RAB27B)

UAR:	123787410(RAB27B)

ELK:

111154292

LLV:

125082367

MPUF:

101677165(RAB27B)

MNP:	132023638(RAB27B)

MLK:	131810829(RAB27B)

NVS:	122902865(RAB27B)

ORO:	101385917(RAB27B)

EJU:	114208857(RAB27B)

ZCA:	113913237(RAB27B)

MLX:	118004486(RAB27B)

NSU:	110576885(RAB27B)

LWW:

102745642

FCA:	101096852(RAB27B)

PYU:	121032903(RAB27B)

PCOO:

112868309(RAB27B)

PBG:	122470787(RAB27B)

PVIV:

125149540(RAB27B)

LRUF:

124517097

PTG:	102957779(RAB27B)

PPAD:

109275693(RAB27B)

PUC:

125914578

AJU:

106981248

HHV:	120247386(RAB27B)

BTA:	282858(RAB27B)

BOM:	102283404(RAB27B)

BIU:	109577923(RAB27B)

BBUB:

102395947(RAB27B)

BBIS:

104999261(RAB27B)

CHX:	102188005(RAB27B)

OAS:	101120036(RAB27B)

BTAX:

128067519(RAB27B)

ODA:	120880971(RAB27B)

CCAD:

122425380(RAB27B)

MBEZ:

129549867(RAB27B)

SSC:	100154771(RAB27B)

CFR:	102509333(RAB27B)

CBAI:

105073934(RAB27B)

CDK:	105103590(RAB27B)

VPC:	102530634(RAB27B)

BACU:

102997283(RAB27B)

BMUS:

118880219(RAB27B)

LVE:	103087022(RAB27B)

OOR:	101286677(RAB27B)

DLE:	111180243(RAB27B)

PCAD:

102989975(RAB27B)

PSIU:

116739348(RAB27B)

NASI:

112407495(RAB27B)

ECB:	100049861(RAB27B)

EPZ:	103547438(RAB27B)

EAI:	106834873(RAB27B)

MYB:	102242977(RAB27B)

MYD:	102765311(RAB27B)

MMYO:

118662791(RAB27B)

MLF:	102438698(RAB27B)

PKL:	118707508(RAB27B)

EFUS:

103293298(RAB27B)

MNA:	107546648(RAB27B)

DRO:	112322661(RAB27B)

SHON:

118978844(RAB27B)

AJM:	119054121(RAB27B)

PDIC:

114506474(RAB27B)

PHAS:

123826121(RAB27B)

MMF:	118618867(RAB27B)

PPAM:

129078733(RAB27B)

HAI:	109381756(RAB27B)

RFQ:	117011847(RAB27B)

PALE:

102884771(RAB27B)

PGIG:

120585012(RAB27B)

PVP:	105292744(RAB27B)

RAY:	107502189(RAB27B)

MJV:	108395140(RAB27B)

TOD:	119243026(RAB27B)

SARA:

101553544(RAB27B)

SETR:

126020655(RAB27B)

LAV:	100666150(RAB27B)

TMU:

101360765

ETF:	101650329(RAB27B)

DNM:	101422271(RAB27B)

MDO:	100016702(RAB27B)

GAS:	123252137(RAB27B)

SHR:	100927480(RAB27B)

AFZ:

127543483

PCW:	110213891(RAB27B)

OAA:	100078959(RAB27B)

APLA:

101793327(RAB27B)

ACYG:

106044917(RAB27B)

CATA:

118254621(RAB27B)

AFUL:

116500702(RAB27B)

FPG:	101918533(RAB27B)

FCH:	102057398(RAB27B)

CLV:	102095757(RAB27B)

EGZ:	104125006(RAB27B)

NNI:	104010835(RAB27B)

PCRI:

104035740(RAB27B)

PLET:

104618877(RAB27B)

EHS:	104512903(RAB27B)

PCAO:

104039325(RAB27B)

ACUN:

113489851(RAB27B)

TALA:

104369282(RAB27B)

PADL:

103916111(RAB27B)

AFOR:

103895208(RAB27B)

ACHC:

115337128(RAB27B)

HALD:

104317284(RAB27B)

HLE:	104841397(RAB27B)

AGEN:

126035612

GCL:

127027480

CCRI:

104159050(RAB27B)

CSTI:

104560816(RAB27B)

CMAC:

104472948(RAB27B)

BREG:

104638023(RAB27B)

FGA:	104083268(RAB27B)

GSTE:

104250247(RAB27B)

LDI:	104344408(RAB27B)

MNB:	103769193(RAB27B)

OHA:	104339062(RAB27B)

SHAB:

115603180(RAB27B) 115618499

PGUU:

104464841(RAB27B)

CPEA:

104393252(RAB27B)

AVIT:

104266987(RAB27B)

CVF:	104283809(RAB27B)

RTD:	128902089 128902966

TEO:	104377412(RAB27B)

BRHI:

104500364

AAM:	106487030(RAB27B)

AROW:

112971458(RAB27B)

NPD:	112946950(RAB27B)

TGT:	104571267(RAB27B)

DNE:	112994462(RAB27B)

SCAM:

104138478(RAB27B)

ASN:	102380724(RAB27B)

AMJ:	102559444(RAB27B)

CPOO:

109307724(RAB27B)

PSS:	102446743(RAB27B)

CMY:	102938304(RAB27B)

CCAY:

125636778(RAB27B)

DCC:	119855912(RAB27B)

CPIC:

101944304(RAB27B)

TST:	117879251(RAB27B)

CABI:

116817578(RAB27B)

MRV:	120408310(RAB27B)

ACS:	100558750(rab27b)

ASAO:

132766885(RAB27B)

PVT:	110082629(RAB27B)

SUND:

121923862(RAB27B)

PBI:	103059662(RAB27B)

PMUR:

107296804(RAB27B)

CTIG:

120298323(RAB27B)

TSR:

106552224

PGUT:

117654717(RAB27B)

APRI:

131191998(RAB27B)

PTEX:

113445780(RAB27B)

NSS:	113411351(RAB27B)

VKO:	123024091(RAB27B)

PMUA:

114606383(RAB27B)

PRAF:

128423206(RAB27B)

ZVI:	118077144(RAB27B)

HCG:	128345200(RAB27B)

GJA:	107114045(RAB27B)

STOW:

125436661(RAB27B)

EMC:	129335222(RAB27B)

XLA:	414551(rab27b.L) 432237(rab27b.S)

XTR:	448182(rab27b)

NPR:	108798508(RAB27B)

RTEM:

120926939(RAB27B)

BBUF:

120992216(RAB27B)

BGAR:

122924863(RAB27B)

MUO:	115462893(RAB27B)

GSH:	117355488(RAB27B)

DRE:	561717(rab27b)

SRX:

107717702

SANH:

107675803(rab27b) 107677856

SGH:	107563270 107564485

CCAR:

109096631(rab27b) 109099350

CAUA:

113039084 113064481 113082898

CGIB:

127941575 127986464

PTET:

122340954(rab27b)

LROH:

127152321(rab27b)

OMC:	131529042(rab27b)

PPRM:

120473966(rab27b)

RKG:	130073091(rab27b)

MAMB:

125253031(rab27b)

CIDE:

127503620

MASI:

127429279 127430874

TROS:

130569953(rab27b)

TDW:	130407568(rab27b)

MANU:

129424073(rab27b)

IPU:	100528562(rab27b)

IFU:	128621999(rab27b)

PHYP:

113535477(rab27b)

SMEO:

124397711(rab27b)

TFD:	113634053(rab27b)

TVC:	132860346(rab27b)

AMEX:

103022885(rab27b)

CMAO:

118820039(rab27b)

EEE:	113591673(rab27b)

CHAR:

105911492(rab27b)

TRU:	101067730 101071476

TFS:	130517697(rab27b) 130526384

TNG:	GSTEN00006789G001 GSTEN00019573G001

LCO:	104919002 104935727

NCC:	104961198 104963949

TBEN:

117472439 117478873(rab27b)

CGOB:

115013116 115016870(rab27b)

PGEO:

117451953 117456431(rab27b)

GACU:

117542932 117552036

EMAC:

134868950(rab27b) 134874239

ELY:	117252526 117269998

EFO:	125890682 125906201

PLEP:

121944052 121959969

SLUC:

116034725(rab27b) 116054334

ECRA:

117945536 117958971(rab27b)

ESP:	116689149 116704167

PFLV:

114555379 114570853

GAT:	120830380 120831536

PPUG:

119224733 119226911

AFB:	129101478 129102541

CLUM:

117736790 117740497(rab27b)

PSWI:

130197260 130205554(rab27b)

MSAM:

119892493 119914539(rab27b)

SCHU:

122865507(rab27b) 122875843

CUD:	121510080 121525069(rab27b)

ALAT:

119020096 119030029

MZE:	101472676(rab27b) 101477650

ONL:	100694577(rab27b) 100706684

OAU:	116324882(rab27b) 116325645

OLA:	101161176(rab27b) 101172416

OML:	112144155(rab27b) 112148410

CSAI:

133451164 133455537(rab27b)

XMA:	102229808 102232710

XCO:	114149664 114154004

XHE:	116724778(rab27b) 116730059

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122819764(rab27b) 122828698

PPRL:

129352051 129353019 129365778

CVG:	107085183 107095580(rab27b)

CTUL:

119784888(rab27b) 119793035

GMU:	124872458(rab27b) 124877930

NFU:	107385993(rab27b) 107397152

KMR:	108228659(rab27b) 108233543

ALIM:

106528918 106532394

NWH:	119424273(rab27b)

AOCE:

111580390 111585486

MCEP:

124997115(rab27b) 125012400

CSEM:

103389106 103397214 103397608

POV:	109637145 109641437

SSEN:

122758548(rab27b) 122769579

HHIP:

117768130 117771382(rab27b)

HSP:	118098094(rab27b) 124852374

SMAU:

118285203(rab27b) 118314494

LCF:	108877068 108889464 108901139 108901141

SDU:	111221141 111236520

SLAL:

111654931 111666803 111669337

XGL:	120805015 120805931(rab27b)

HCQ:	109518151 109525204

SSCV:

125979441 125994192

SBIA:

133490979(rab27b) 133499690

PEE:	133400116 133413789(rab27b)

PTAO:

133465040(rab27b) 133474888

BPEC:

110154371 110172497(rab27b)

MALB:

109953033 109960708

BSPL:

114861281 114866693

SJO:	128365090 128380032(rab27b)

SASA:

100196212(rb27b) 106572338 106585376 106585730 106590748

STRU:

115149553 115160162 115164778 115199875

OTW:	112232843 112237540 112239981(rab27b) 112263141

OMY:	110524935 110525428 110535819 110536882

OGO:	123989559 123999440 124034495 124036109

ONE:	115111393 115123075 115139829

OKI:	109877144 109879709 109884327 109895717

OKE:	118358132 118392995 127906465 127931677

SALP:

111958270 111974510 112074658 112076265

SNH:	120026029 120044200(rab27b) 120054970 120062695

CCLU:

121551131 121559088(rab27b) 121581837 121584653

ELS:	105014697 105020521(rab27b)

SFM:	108933573(rab27b)

PKI:

111843795

AANG:

118213468(rab27b) 118237354

LOC:	102694396(rab27b)

PSPA:

121304394(rab27b) 121317961

ARUT:

117421298(rab27b)

PSEX:

120527243(rab27b)

LCM:	102365051(RAB27B)

CMK:	103184853(rab27b)

CPLA:

122565458(rab27b)

HOC:	132832561(rab27b)

LERI:

129713063(rab27b)

CIN:

SCLV:

PMEO:

OBI:

OSN:

PSYT:

DSAG12_02513(der_2)

» show all

Reference

PMID:19966785

Authors

Ostrowski M, Carmo NB, Krumeich S, Fanget I, Raposo G, Savina A, Moita CF, Schauer K, Hume AN, Freitas RP, Goud B, Benaroch P, Hacohen N, Fukuda M, Desnos C, Seabra MC, Darchen F, Amigorena S, Moita LF, Thery C

Title

Rab27a and Rab27b control different steps of the exosome secretion pathway.

Journal

Nat Cell Biol 12:19-30; sup pp 1-13 (2010)
DOI:10.1038/ncb2000

Sequence

[hsa:5874]

Reference

PMID:15451418

Authors

Chen X, Li C, Izumi T, Ernst SA, Andrews PC, Williams JA

Title

Rab27b localizes to zymogen granules and regulates pancreatic acinar exocytosis.

Journal

Biochem Biophys Res Commun 323:1157-62 (2004)
DOI:10.1016/j.bbrc.2004.08.212

Sequence

[rno:84590]

All links

Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Gene (817)   
   KEGG GENES (480)   
   KEGG MGENES (117)   
   RefGene (214)   
   OC (6)   
Literature (2)   
   PubMed (2)   
All databases (825)   

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