KEGG   ORTHOLOGY: K08011Help
Entry
K08011                      KO                                     

Name
NCF1, P47PHOX
Definition
neutrophil cytosolic factor 1
Pathway
Chemokine signaling pathway
Phagosome
Osteoclast differentiation
Fc gamma R-mediated phagocytosis
Leukocyte transendothelial migration
Leishmaniasis
Disease
H00098  
Chronic granulomatous disease
H01167  
Gluconobacter infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    K08011  NCF1, P47PHOX; neutrophil cytosolic factor 1
 Organismal Systems
  Immune system
   04666 Fc gamma R-mediated phagocytosis
    K08011  NCF1, P47PHOX; neutrophil cytosolic factor 1
   04670 Leukocyte transendothelial migration
    K08011  NCF1, P47PHOX; neutrophil cytosolic factor 1
   04062 Chemokine signaling pathway
    K08011  NCF1, P47PHOX; neutrophil cytosolic factor 1
  Development
   04380 Osteoclast differentiation
    K08011  NCF1, P47PHOX; neutrophil cytosolic factor 1
 Human Diseases
  Infectious diseases
   05140 Leishmaniasis
    K08011  NCF1, P47PHOX; neutrophil cytosolic factor 1
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
653361(NCF1)
PTR: 
743307(NCF1)
PPS: 
100976968(NCF1)
GGO: 
PON: 
100442050(NCF1)
MCC: 
694207(NCF1)
MCF: 
102124562(NCF1)
MMU: 
17969(Ncf1)
RNO: 
114553(Ncf1)
CGE: 
100769204(Ncf1)
HGL: 
101721191(Ncf1)
TUP: 
102502283(NCF1)
CFA: 
607700(NCF1)
AML: 
FCA: 
101098840(NCF1)
PTG: 
102958576(NCF1)
BTA: 
281345(NCF1)
BOM: 
102266557(NCF1)
PHD: 
102340834(NCF1)
CHX: 
102176291(NCF1)
SSC: 
100134857(NCF1)
CFR: 
102503581(NCF1)
BACU: 
LVE: 
103072544(NCF1)
ECB: 
100146522(NCF1)
MYB: 
MYD: 
PALE: 
102886343(NCF1)
MDO: 
100014144(NCF1)
SHR: 
OAA: 
GGA: 
417485(NCF1)
MGP: 
TGU: 
101234037(NCF1)
FAB: 
101806380(NCF1)
PHI: 
102099699(NCF1)
APLA: 
101802365(NCF1)
FPG: 
101913107(NCF1)
FCH: 
102060078(NCF1)
CLV: 
102091881(NCF1)
ASN: 
102381152(NCF1)
AMJ: 
102576900(NCF1)
PSS: 
102463356(NCF1)
CMY: 
102948027(NCF1)
ACS: 
PBI: 
103053417(NCF1)
XTR: 
100124318(ncf1)
DRE: 
378966(ncf1)
TRU: 
445890(p47phox)
MZE: 
OLA: 
XMA: 
LCM: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Sumimoto H
  Title
Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species.
  Journal
FEBS J 275:3249-77 (2008)
Reference
PMID:2547247
  Authors
Lomax KJ, Leto TL, Nunoi H, Gallin JI, Malech HL
  Title
Recombinant 47-kilodalton cytosol factor restores NADPH oxidase in chronic granulomatous disease.
  Journal
Science 245:409-12 (1989)

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