KEGG   ORTHOLOGY: K08048Help
Entry
K08048                      KO                                     

Name
ADCY8
Definition
adenylate cyclase 8 [EC:4.6.1.1]
Pathway
Purine metabolism
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
Oocyte meiosis
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
GABAergic synapse
Taste transduction
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Ovarian steroidogenesis
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Oxytocin signaling pathway
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Bile secretion
Morphine addiction
HTLV-I infection
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Nucleotide metabolism
   00230 Purine metabolism
    K08048  ADCY8; adenylate cyclase 8
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    K08048  ADCY8; adenylate cyclase 8
   04020 Calcium signaling pathway
    K08048  ADCY8; adenylate cyclase 8
   04022 cGMP - PKG signaling pathway
    K08048  ADCY8; adenylate cyclase 8
 Cellular Processes
  Cell growth and death
   04114 Oocyte meiosis
    K08048  ADCY8; adenylate cyclase 8
  Cell communication
   04540 Gap junction
    K08048  ADCY8; adenylate cyclase 8
 Organismal Systems
  Immune system
   04611 Platelet activation
    K08048  ADCY8; adenylate cyclase 8
   04062 Chemokine signaling pathway
    K08048  ADCY8; adenylate cyclase 8
  Endocrine system
   04911 Insulin secretion
    K08048  ADCY8; adenylate cyclase 8
   04912 GnRH signaling pathway
    K08048  ADCY8; adenylate cyclase 8
   04913 Ovarian Steroidogenesis
    K08048  ADCY8; adenylate cyclase 8
   04915 Estrogen signaling pathway
    K08048  ADCY8; adenylate cyclase 8
   04914 Progesterone-mediated oocyte maturation
    K08048  ADCY8; adenylate cyclase 8
   04921 Oxytocin signaling pathway
    K08048  ADCY8; adenylate cyclase 8
   04918 Thyroid hormone synthesis
    K08048  ADCY8; adenylate cyclase 8
   04916 Melanogenesis
    K08048  ADCY8; adenylate cyclase 8
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K08048  ADCY8; adenylate cyclase 8
   04270 Vascular smooth muscle contraction
    K08048  ADCY8; adenylate cyclase 8
  Digestive system
   04970 Salivary secretion
    K08048  ADCY8; adenylate cyclase 8
   04971 Gastric acid secretion
    K08048  ADCY8; adenylate cyclase 8
   04972 Pancreatic secretion
    K08048  ADCY8; adenylate cyclase 8
   04976 Bile secretion
    K08048  ADCY8; adenylate cyclase 8
  Nervous system
   04724 Glutamatergic synapse
    K08048  ADCY8; adenylate cyclase 8
   04727 GABAergic synapse
    K08048  ADCY8; adenylate cyclase 8
   04725 Cholinergic synapse
    K08048  ADCY8; adenylate cyclase 8
   04720 Long-term potentiation
    K08048  ADCY8; adenylate cyclase 8
   04723 Retrograde endocannabinoid signaling
    K08048  ADCY8; adenylate cyclase 8
  Sensory system
   04742 Taste transduction
    K08048  ADCY8; adenylate cyclase 8
   04750 Inflammatory mediator regulation of TRP channels
    K08048  ADCY8; adenylate cyclase 8
  Environmental adaptation
   04713 Circadian entrainment
    K08048  ADCY8; adenylate cyclase 8
 Human Diseases
  Substance dependence
   05032 Morphine addiction
    K08048  ADCY8; adenylate cyclase 8
  Cardiovascular diseases
   05414 Dilated cardiomyopathy (DCM)
    K08048  ADCY8; adenylate cyclase 8
  Infectious diseases
   05166 HTLV-I infection
    K08048  ADCY8; adenylate cyclase 8
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     K08048  ADCY8; adenylate cyclase 8
BRITE hierarchy
Other DBs
Genes
HSA: 
114(ADCY8)
PTR: 
PPS: 
100994715(ADCY8)
GGO: 
101142672(ADCY8)
PON: 
MCC: 
695792(ADCY8)
MCF: 
102144854(ADCY8)
MMU: 
11514(Adcy8)
RNO: 
29241(Adcy8)
HGL: 
101698293(Adcy8)
TUP: 
102472317(ADCY8)
CFA: 
482045(ADCY8)
AML: 
100474121(ADCY8)
FCA: 
101087555(ADCY8)
PTG: 
102948581(ADCY8)
BTA: 
535017(ADCY8)
BOM: 
102272964(ADCY8)
PHD: 
102315306(ADCY8)
CHX: 
102184919(ADCY8)
SSC: 
CFR: 
102521259(ADCY8)
ECB: 
100057796(ADCY8)
MYB: 
102249345(ADCY8)
MYD: 
102765722(ADCY8)
PALE: 
102896789(ADCY8)
MDO: 
100026554(ADCY8)
SHR: 
100923926(ADCY8)
OAA: 
100077908(ADCY8)
GGA: 
420328(ADCY8)
MGP: 
100548951(ADCY8)
TGU: 
100230277(ADCY8)
FAB: 
101809046(ADCY8)
PHI: 
102108193(ADCY8)
APLA: 
101794043(ADCY8)
FPG: 
101921528(ADCY8)
FCH: 
102056487(ADCY8)
CLV: 
102086133(ADCY8)
ASN: 
102369910(ADCY8)
PSS: 
102448969(ADCY8)
CMY: 
102930804(ADCY8)
ACS: 
100556578(adcy8)
XTR: 
DRE: 
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
BFO: 
CIN: 
DME: 
DPO: 
DAN: 
DER: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
726262(GB19497)
NVI: 
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
AQU: 
DFA: 
DFA_04345(acaA)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9140089
  Authors
Hanoune J, Pouille Y, Tzavara E, Shen T, Lipskaya L, Miyamoto N, Suzuki Y, Defer N
  Title
Adenylyl cyclases: structure, regulation and function in an enzyme superfamily.
  Journal
Mol Cell Endocrinol 128:179-94 (1997)
Reference
  Authors
Defer N, Best-Belpomme M, Hanoune J
  Title
Tissue specificity and physiological relevance of various isoforms of adenylyl cyclase.
  Journal
Am J Physiol Renal Physiol 279:F400-16 (2000)

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