KEGG   ORTHOLOGY: K08775Help
Entry
K08775                      KO                                     

Name
BRCA2, FANCD1
Definition
breast cancer 2 susceptibility protein
Pathway
Homologous recombination
Fanconi anemia pathway
Pathways in cancer
Pancreatic cancer
Disease
H00019  
Pancreatic cancer
H00027  
Ovarian cancer
H00031  
Breast cancer
H00238  
Fanconi anemia
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Replication and repair
   03440 Homologous recombination
    K08775  BRCA2, FANCD1; breast cancer 2 susceptibility protein
   03460 Fanconi anemia pathway
    K08775  BRCA2, FANCD1; breast cancer 2 susceptibility protein
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K08775  BRCA2, FANCD1; breast cancer 2 susceptibility protein
   05212 Pancreatic cancer
    K08775  BRCA2, FANCD1; breast cancer 2 susceptibility protein
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  multi subunit Ring-finger type E3
   BRCC complex
    K08775  BRCA2, FANCD1; breast cancer 2 susceptibility protein
Chromosome [BR:ko03036]
 Eukaryotic Type
  Centrosomal proteins
   Centrosome duplication proteins
    Other centrosome duplication proteins
     K08775  BRCA2, FANCD1; breast cancer 2 susceptibility protein
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    Other HR factors
     K08775  BRCA2, FANCD1; breast cancer 2 susceptibility protein
   FA (Fanconi anemia) pathway
    Downstream FA components
     K08775  BRCA2, FANCD1; breast cancer 2 susceptibility protein
BRITE hierarchy
Genes
HSA: 
675(BRCA2)
PTR: 
452526(BRCA2)
PPS: 
100976403(BRCA2)
GGO: 
101126719(BRCA2)
PON: 
100435800(BRCA2)
MCC: 
721981(BRCA2)
MCF: 
102140332(BRCA2)
MMU: 
12190(Brca2)
RNO: 
360254(Brca2)
CGE: 
100689197(Brca2)
HGL: 
101698015(Brca2)
TUP: 
102491921(BRCA2)
CFA: 
474180(BRCA2)
AML: 
FCA: 
493878(BRCA2)
PTG: 
102965865(BRCA2)
BTA: 
507069(BRCA2)
BOM: 
102276437(BRCA2)
PHD: 
102315726(BRCA2)
CHX: 
102182417(BRCA2)
SSC: 
100153762(BRCA2)
CFR: 
102515425(BRCA2)
ECB: 
100064578(BRCA2)
MYB: 
102245665(BRCA2)
MYD: 
102773822(BRCA2)
PALE: 
102896802(BRCA2)
MDO: 
100049015(BRCA2)
SHR: 
100915673(BRCA2)
OAA: 
100079887(BRCA2)
GGA: 
374139(BRCA2)
MGP: 
TGU: 
100218603(BRCA2)
FAB: 
101819655(BRCA2)
PHI: 
102113036(BRCA2)
APLA: 
101799101(BRCA2)
FPG: 
101912402(BRCA2)
FCH: 
102052685(BRCA2)
CLV: 
102091608(BRCA2)
ASN: 
102383360(BRCA2)
PSS: 
102455975(BRCA2)
CMY: 
102945068(BRCA2)
ACS: 
XTR: 
100038818(brca2)
DRE: 
566758(brca2)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102351607(BRCA2)
SPU: 
584780(brca2)
AGA: 
AAG: 
CQU: 
AME: 
725687(GB17004)
BMOR: 
API: 
PHU: 
ISC: 
TSP: 
SMM: 
NVE: 
ATH: 
AT4G00020(BRCA2(IV)) AT5G01630(BRCA2B)
ALY: 
CRB: 
EUS: 
CIT: 
CIC: 
TCC: 
GMX: 
MTR: 
CAM: 
FVE: 
CSV: 
RCU: 
POP: 
POPTR_0014s19050g(POPTRDRAFT_573323)
VVI: 
SLY: 
SOT: 
OBR: 
BDI: 
SBI: 
SORBI_0013s007040(SORBIDRAFT_0013s007040)
SITA: 
ATR: 
s00023p00030650(AMTR_s00023p00030650)
OLU: 
OTA: 
MIS: 
MPP: 
CSL: 
CVR: 
GSL: 
CCP: 
CNE: 
CNB: 
CGI: 
PPL: 
LBC: 
CCI: 
SCM: 
UMA: 
PGR: 
DDI: 
DPP: 
DFA: 
ACAN: 
TPS: 
NGR: 
TVA: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Jacquemont C, Taniguchi T
  Title
The Fanconi anemia pathway and ubiquitin.
  Journal
BMC Biochem 8 Suppl 1:S10 (2007)
Reference
  Authors
Holloman WK
  Title
Unraveling the mechanism of BRCA2 in homologous recombination.
  Journal
Nat Struct Mol Biol 18:748-54 (2011)

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