KEGG   ORTHOLOGY: K09187Help
Entry
K09187                      KO                                     
Name
MLL2, ALR
Definition
histone-lysine N-methyltransferase MLL2 [EC:2.1.1.43]
Pathway
Lysine degradation
Disease
H00570  
Kabuki syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Amino acid metabolism
   00310 Lysine degradation
    K09187  MLL2, ALR; histone-lysine N-methyltransferase MLL2
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.43  histone-lysine N-methyltransferase
     K09187  MLL2, ALR; histone-lysine N-methyltransferase MLL2
Transcription factors [BR:ko03000]
 Eukaryotic Type
  Zinc finger
   Cys4 Trithorax
    K09187  MLL2, ALR; histone-lysine N-methyltransferase MLL2
Chromosome [BR:ko03036]
 Eukaryotic Type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     K09187  MLL2, ALR; histone-lysine N-methyltransferase MLL2
   HMT complexes
    MLL-HCF complex
     K09187  MLL2, ALR; histone-lysine N-methyltransferase MLL2
BRITE hierarchy
Other DBs
Genes
HSA: 
8085(MLL2)
PTR: 
PPS: 
100995808(MLL2)
GGO: 
101144774(MLL2)
PON: 
100441715(MLL2)
MCC: 
710795(MLL2)
MMU: 
381022(Mll2)
RNO: 
CFA: 
486558(MLL2)
AML: 
100479447(MLL2)
FCA: 
101095268(MLL2)
BTA: 
506805(MLL2)
SSC: 
100513150
SHR: 
100928575(MLL2)
TGU: 
100226907
ACS: 
100554175
XTR: 
100494109
TRU: 
101062458
OLA: 
101172242
CIN: 
778537(alr-like)
TAD: 
TRIADDRAFT_62004
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Andreu-Vieyra CV, Chen R, Agno JE, Glaser S, Anastassiadis K, Stewart AF, Matzuk MM
  Title
MLL2 is required in oocytes for bulk histone 3 lysine 4 trimethylation and transcriptional silencing.
  Journal
PLoS Biol 8 (2010)
Reference
  Authors
Ansari KI, Mandal SS
  Title
Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing.
  Journal
FEBS J 277:1790-804 (2010)
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