KEGG ORTHOLOGY: K09189

ORTHOLOGY: K09189

Entry

K09189 KO

Name

MLL5

Definition

histone-lysine N-methyltransferase MLL5 [EC:2.1.1.43]

Pathway

ko00310

Lysine degradation

Brite

KEGG Orthology (KO) [BR:ko00001]
Metabolism
  Amino acid metabolism
   00310 Lysine degradation
    K09189  MLL5; histone-lysine N-methyltransferase MLL5
Enzymes [BR:ko01000]
2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.43  histone-lysine N-methyltransferase
     K09189  MLL5; histone-lysine N-methyltransferase MLL5
Transcription factors [BR:ko03000]
Eukaryotic Type
  Zinc finger
   Cys4 Trithorax
    K09189  MLL5; histone-lysine N-methyltransferase MLL5
Chromosome [BR:ko03036]
Eukaryotic Type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     K09189  MLL5; histone-lysine N-methyltransferase MLL5

Other DBs

RN:

R03875 R04866 R04867

GO:

0042800

Genes

HSA:	55904(MLL5)
PTR:	463640(MLL5)
PPS:	100982828(MLL5)
GGO:	101143612
PON:	100173903(MLL5)
MCC:	697233
MMU:	69188(Mll5)
RNO:	311968(Mll5)
CFA:	475895(MLL5)
AML:	100468393
FCA:	101084945(MLL5)
BTA:	539121(MLL5)
SSC:	100628131(MLL5)
ECB:	100058928(MLL5)
SHR:	100922144(MLL5)
OAA:	100077208(MLL5)
GGA:	417712(MLL5)
MGP:	100545555
TGU:	100226399(MLL5)
ACS:	100553183(mll5)
XTR:	779539(mll5)
DRE:	325395(mll5)
TRU:	101076756
OLA:	101162568
BFO:	BRAFLDRAFT_76037
CIN:	100180251
SPU:	580083
AME:	100577280
NVI:	100114564(NV16583)
TCA:	658527
API:	100161573
PHU:	Phum_PHUM494030
ISC:	IscW_ISCW020048
TSP:	Tsp_08530
SMM:	Smp_161010
TAD:	TRIADDRAFT_61865

» show all

Reference

PMID:14718661

Authors

Deng LW, Chiu I, Strominger JL

Title

MLL 5 protein forms intranuclear foci, and overexpression inhibits cell cycle progression.

Journal

Proc Natl Acad Sci U S A 101:757-62 (2004)

Reference

PMID:20236313

Authors

Ansari KI, Mandal SS

Title

Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing.

Journal

FEBS J 277:1790-804 (2010)

All links

Ontology (5)   
   KEGG BRITE (4)   
   GO (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (8)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
   KEGG RCLASS (4)   
Gene (75)   
   KEGG GENES (36)   
   KEGG DGENES (5)   
   KEGG EGENES (30)   
   KEGG MGENES (4)   
Protein sequence (9)   
   UniProt (9)   
Literature (2)   
   PubMed (2)   
All databases (101)   

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