KEGG ORTHOLOGY: K09367

ORTHOLOGY: K09367

Entry

K09367                      KO

Symbol

POU5F

Name

POU domain transcription factor, class 5

Pathway

map04550

Signaling pathways regulating pluripotency of stem cells

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K09367  POU5F; POU domain transcription factor, class 5
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K09367  POU5F; POU domain transcription factor, class 5
   03021 Transcription machinery
    K09367  POU5F; POU domain transcription factor, class 5
Transcription factors [BR:ko03000]
Eukaryotic type
  Helix-turn-helix
   Homeo domain POU
    K09367  POU5F; POU domain transcription factor, class 5
Transcription machinery [BR:ko03021]
Eukaryotic type
  RNA polymerase III system
   Other transcription-related factors
    Octamer transcription factors
     K09367  POU5F; POU domain transcription factor, class 5

Genes

HSA:	5460(POU5F1) 5462(POU5F1B)

PTR:	472858(POU5F1B) 744263(POU5F1)

PPS:	100972855(POU5F1B) 100985881 100994428(POU5F1)

GGO:	101127809(POU5F1B) 101138823(POU5F1) 109026315

PON:	100434703(POU5F1) 100436058 100456032(POU5F1B)

HMH:	116460100(POU5F1)

MCC:	114675366 714760(POU5F1)

MCF:	102115117(POU5F1)

MTHB:

126953078

MNI:	105498636(POU5F1)

CSAB:

103221803(POU5F1)

CATY:

105600008(POU5F1)

PANU:

101003706(POU5F1) 116272643

MLEU:

105533262(POU5F1)

RRO:	104666216(POU5F1)

RBB:	108522583(POU5F1)

TFN:	117062304 117084906 117088422(POU5F1)

PTEH:

111527856(POU5F1)

CANG:

105513939(POU5F1)

CJC:	100384946(POU5F1)

SBQ:	101031159(POU5F1)

CIMI:

108295656 108297402(POU5F1)

CSYR:

103274281(POU5F1) 103275231

MMUR:

105858177(POU5F1) 105866315 105868767

LCAT:

123631714(POU5F1)

PCOQ:

105817295(POU5F1)

OGA:	100956582(POU5F1)

MMU:	18999(Pou5f1)

MCAL:

110284046(Pou5f1)

MPAH:

110335741(Pou5f1)

RNO:	294562(Pou5f1)

MCOC:

116074631(Pou5f1)

ANU:	117724197 117724609(Pou5f1)

MUN:	110557159(Pou5f1)

CGE:	100754998(Pou5f1)

MAUA:

101830841(Pou5f1)

PROB:

127223875(Pou5f1)

PLEU:

114705855(Pou5f1)

MORG:

121435622(Pou5f1)

MFOT:

126495510 126502923

AAMP:

119811875 119813506 119823921(Pou5f1)

NGI:	103739849(Pou5f1)

HGL:	101722299(Pou5f1)

CPOC:

100724951(Pou5f1)

CCAN:

109700910

DORD:

105996959(Pou5f1)

DSP:	122111327(Pou5f1)

PLOP:

125352796(Pou5f1)

NCAR:

124988936

MMMA:

107160473(Pou5f1)

OCU:	100101567(POU5F1)

OPI:	101527772(POU5F1)

TUP:	102480369(POU5F1)

GVR:	103606649(POU5F1)

CFA:

481709

CLUD:

112641184(POU5F1)

VVP:	112913800(POU5F1)

VLG:	121499434(POU5F1)

NPO:	129512642(POU5F1)

AML:	100475658 100480318(POU5F1)

UMR:	103665021(POU5F1)

UAH:	113264185(POU5F1)

UAR:	123794134(POU5F1)

ELK:

111152324

LLV:

125101806

MPUF:

101690377(POU5F1)

MNP:	132017181(POU5F1)

MLK:	131833236(POU5F1)

NVS:	122911898(POU5F1)

ORO:	101386310(POU5F1)

EJU:	114199258(POU5F1)

ZCA:	113917449 113927991(POU5F1)

MLX:	118027257(POU5F1)

NSU:	110586710(POU5F1)

LWW:	102744645(POU5F1)

FCA:	100174788(POU5F1)

PYU:	121023129(POU5F1)

PCOO:

112853654(POU5F1)

PBG:	122489344(POU5F1)

PVIV:

125165808(POU5F1)

LRUF:

124528963

PTG:	102970937(POU5F1)

PPAD:

109249413(POU5F1)

PUC:

125938472

AJU:

106966641

HHV:	120222669(POU5F1)

BTA:	132345822 282316(POU5F1)

BOM:	102279076(POU5F1)

BIU:	109577081(POU5F1)

BBUB:

102395613(POU5F1)

BBIS:

104983476(POU5F1) 104991815

CHX:	100860952(POU5F1)

OAS:	100302349(POU5F1) 101110340

BTAX:

128055283(POU5F1) 128066203

ODA:	120862723 120870514(POU5F1)

CCAD:

122429599(POU5F1)

MBEZ:

129543617(POU5F1)

SSC:	100127461(POU5F1)

CFR:	102503726(POU5F1) 102517736

CBAI:

105072455 105074128(POU5F1)

CDK:	105087524 116147757

VPC:	102540115(POU5F1)

BACU:

103008706(POU5F1)

BMUS:

118895851 118903668(POU5F1)

LVE:	103077875(POU5F1)

OOR:	101272336(POU5F1)

DLE:	111170645(POU5F1)

PCAD:

102984651(POU5F1)

PSIU:

116761843(POU5F1)

NASI:

112395460(POU5F1)

ECB:	100050785(POU5F1)

EPZ:	103540785(POU5F1)

EAI:	106829125(POU5F1)

MYB:	102252063(POU5F1)

MYD:	102754035(POU5F1)

MMYO:

118656212 118679621(POU5F1)

MLF:	102440458(POU5F1)

PKL:	118716978(POU5F1)

EFUS:

103300484(POU5F1)

MNA:	107538508(POU5F1)

DRO:	112302250(POU5F1)

SHON:

118987597(POU5F1)

AJM:	119053762(POU5F1)

PDIC:

114492309 114494681(POU5F1) 114505241

PHAS:

123810426(POU5F1)

MMF:	118621789(POU5F1)

PPAM:

129067301(POU5F1) 129082304

HAI:	109376090(POU5F1)

RFQ:	117020249(POU5F1) 117032886 117033819

PALE:

102885434(POU5F1)

PGIG:

120593405(POU5F1)

PVP:	105308128(POU5F1)

RAY:	107506214(POU5F1)

MJV:	108383650 118973834

TOD:	119252126(POU5F1)

SARA:

101542084(POU5F1)

SETR:

125996456(POU5F1)

LAV:	100662436(POU5F1)

TMU:

101344599

ETF:	101651915(POU5F1)

DNM:	101427273(POU5F1)

MDO:	100022539 103096338(POU5F1)

GAS:	123235150 123247077(POU5F1) 123253604

SHR:	100913730 100927100(POU5F1)

AFZ:	127549111 127561056

PCW:	110199309(POU5F1) 110205300

OAA:	100091458(POU5F1) 114807791

GGA:	427781(Pou5f3)

PCOC:

MGP:

CJO:

TPAI:

LMUT:

NMEL:

APLA:

ACYG:

CATA:

AFUL:

TGU:

LSR:

SCAN:

PMOA:

OTC:

PRUF:

GFR:

FAB:

OMA:

PHI:

PMAJ:

CCAE:

CCW:

CBRC:

ETL:

ZAB:

ACHL:

103811496(POU5F1)

SVG:

MMEA:

HRT:

FPG:

FCH:

CLV:

EGZ:

NNI:

PCRI:

PLET:

104622721(POU5F1)

ACUN:

TALA:

PADL:

AFOR:

ACHC:

HLE:

AGEN:

GCL:

CCRI:

104156596(POU4F1)

FGA:

104074023

SHAB:

115616901

DPUB:

104300181

CPEA:

104397869(NPDC1)

CVF:

RTD:

CUCA:

TEO:

AAM:

AROW:

NPD:

TGT:

DNE:

SCAM:

ASN:	102377154 112550152

AMJ:	102569083(POU5F3) 102574080

CPOO:

109314103

GGN:

109292722

PSS:

102457876

CMY:	102945974 119567476(POU5F1)

CCAY:

125621411(POU5F1) 125623317

DCC:	119842664(POU5F1) 119844397

CPIC:

101949130(POU5F1) 101950391

TST:

117867165

CABI:

116824671 116835976

MRV:	120387027 120392357(POU5F1)

ACS:	100559295(pou5f1)

ASAO:

132765188(POU5F1)

PVT:

SUND:

PBI:

PMUR:

CTIG:

120314244(POU5F1)

PGUT:

117667944(POU5F1)

APRI:

131191172

PTEX:

113449338(POU5F1)

NSS:

113423864

VKO:	123017925(POU5F1)

PRAF:

128408691(POU5F1)

ZVI:	118076074(POU5F1)

HCG:	128348022(POU5F1)

GJA:	107108243(POU5F1)

STOW:

125429202

EMC:	129328168(POU5F1)

XLA:	108699882(pou5f3.2.S) 108699884(pou5f3.1.S) 379522(pou5f3.2.L) 397784(pou5f3.1.L)

XTR:	100170181(pou5f3.2) 100498076(pou5f3.1)

NPR:	108787238 108787260

RTEM:

120914034 120914589 120924645 120924660 120924675

BBUF:

120977144 120977525

BGAR:

122919344 122919886

MUO:

115473199

GSH:	117346326(POU5F1) 117367479

DRE:	30333(pou5f3)

SRX:	107736873 107739697

SANH:

SGH:

CCAR:

CAUA:

CGIB:

PTET:

122326200(pou5f3)

LROH:

127151923(pou5f3)

OMC:	131529111(pou5f3)

PPRM:

120477328(pou5f3)

MAMB:

125252475(pou5f3)

CIDE:

127504250 127525536

MASI:

127429001 127430598

TROS:

130570239(pou5f3)

TDW:	130407437(pou5f3)

MANU:

129424322(pou5f3)

IPU:	108279325(pou5f3)

IFU:	128622118(pou5f3)

PHYP:

113535815

SMEO:

124397931(pou5f3)

TFD:	113640039(pou5f3)

TVC:	132860225(pou5f3)

AMEX:

103030044

CMAO:

118820620(pou5f3)

EEE:

113573417

CHAR:

105912643(pou5f3)

TRU:

101074260

TFS:	130517459(pou5f3)

TNG:	GSTEN00005265G001

LCO:

104936371

NCC:

104955091

TBEN:

117476822(pou5f3)

CGOB:

115016992

PGEO:

117456299(pou5f3)

GACU:

117534082 117534108(pou5f3)

EMAC:

134868106(pou5f3)

ELY:	117269314(pou5f3)

EFO:	125906229(pou5f3)

PLEP:

121959721(pou5f3)

SLUC:

116035117(pou5f3)

ECRA:

117959612(pou5f3)

ESP:

116703937

PFLV:

114571387

GAT:	120832205(pou5f3)

PPUG:

119227101(pou5f3)

AFB:	129102327(pou5f3)

CLUM:

117740555(pou5f3)

PSWI:

130205736(pou5f3)

MSAM:

119914334(pou5f3)

SCHU:

122865771(pou5f3)

CUD:	121525335(pou5f3)

ALAT:

119030023(pou5f3)

MZE:

101482258

ONL:

100706011

OAU:	116335204(pou5f3)

OLA:

100049520

OML:	112163255(pou5f3)

CSAI:

133454693(pou5f3)

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122819240(pou5f3)

PPRL:

129366499(pou5f3)

CVG:

107088696

CTUL:

119782633(pou5f3)

GMU:	124872245(pou5f3)

NFU:

107397331

KMR:	108232625(pou5f3)

ALIM:

106514575

NWH:	119425174(pou5f3)

AOCE:

111582028

MCEP:

124996903(pou5f3)

CSEM:

103389210

POV:

109643506

SSEN:

122787116(pou5f3)

HHIP:

117772126(pou5f3)

HSP:	118125967(pou5f3)

SMAU:

118284499(pou5f3)

LCF:	108879229(pou5f3)

SDU:

111238932

SLAL:

111652983

XGL:	120806346(pou5f3)

HCQ:

109527971

SSCV:

125979563

SBIA:

133490566(pou5f3)

PEE:	133413720(pou5f3)

PTAO:

133465294(pou5f3)

BPEC:

110174202

BSPL:

114867101(pou5f3)

SJO:	128380582(pou5f3)

SASA:

106563125 106567323

STRU:

115159657 115203992

OTW:	112220339 112234371(pou5f3)

OMY:	110509718(pou5f3) 110523509

OGO:	124007303 124049034

ONE:	115128881 115147137

OKI:	109868858 109874174

OKE:	118385512(pou5f3) 118387469

SALP:

111961695 111963955

SNH:	120021873 120026415

CCLU:

121541604(pou5f3) 121582593

ELS:

105014844

SFM:	108922598 108938066

PKI:

111853970

AANG:

118212354(pou5f3)

LOC:

102693253

PSPA:

121299098 121304174 121306672

ARUT:

117396677(pou5f3) 117433601 117964856 117964858 117973862

PSEX:

120535803(pou5f3)

LCM:	102355666 102362664

CMK:

103183084

RTP:	109914645 109922237

CPLA:

122541568 122564647

HOC:	132825636 132832927

LERI:

129695202 129712131

LRJ:

133361176

» show all

Reference

PMID:10742100

Authors

Niwa H, Miyazaki J, Smith AG

Title

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells.

Journal

Nat Genet 24:372-6 (2000)
DOI:10.1038/74199

Sequence

[hsa:5460] [mmu:18999]

Reference

PMID:9368058

Authors

Inamoto S, Segil N, Pan ZQ, Kimura M, Roeder RG

Title

The cyclin-dependent kinase-activating kinase (CAK) assembly factor, MAT1, targets and enhances CAK activity on the POU domains of octamer transcription factors.

Journal

J Biol Chem 272:29852-8 (1997)
DOI:10.1074/jbc.272.47.29852

Sequence

[hsa:5460]

Reference

PMID:18949397

Authors

Panagopoulos I, Moller E, Collin A, Mertens F

Title

The POU5F1P1 pseudogene encodes a putative protein similar to POU5F1 isoform 1.

Journal

Oncol Rep 20:1029-33 (2008)
DOI:10.3892/or_00000105

Sequence

[hsa:5462]

Reference

PMID:24056933

Authors

Lee MT, Bonneau AR, Takacs CM, Bazzini AA, DiVito KR, Fleming ES, Giraldez AJ

Title

Nanog, Pou5f1 and SoxB1 activate zygotic gene expression during the maternal-to-zygotic transition.

Journal

Nature 503:360-4 (2013)
DOI:10.1038/nature12632

Sequence

[dre:30333]

All links

Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Gene (659)   
   KEGG GENES (463)   
   KEGG MGENES (163)   
   RefGene (31)   
   OC (2)   
Literature (4)   
   PubMed (4)   
All databases (668)   

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