KEGG ORTHOLOGY: K09370

ORTHOLOGY: K09370

Entry

K09370                      KO

Symbol

ISL1

Name

insulin gene enhancer protein ISL-1

Pathway

map04550

Signaling pathways regulating pluripotency of stem cells

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K09370  ISL1; insulin gene enhancer protein ISL-1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K09370  ISL1; insulin gene enhancer protein ISL-1
Transcription factors [BR:ko03000]
Eukaryotic type
  Helix-turn-helix
   Homeo domain LIM
    K09370  ISL1; insulin gene enhancer protein ISL-1

Genes

HSA:	3670(ISL1)

PTR:	461881(ISL1)

PPS:	100976744(ISL1)

GGO:	101130866(ISL1)

PON:	100436118(ISL1)

NLE:	100587001(ISL1)

HMH:	116462306(ISL1)

MCC:	705894(ISL1)

MCF:	102130233(ISL1)

MTHB:

126956851

MNI:	105499351(ISL1)

CSAB:

103221252(ISL1)

CATY:

105571991(ISL1)

PANU:

101011645(ISL1)

TGE:	112626236(ISL1)

MLEU:

105534829

RRO:	104663286(ISL1)

RBB:	108542035(ISL1)

TFN:	117065098(ISL1)

PTEH:

111541561(ISL1)

CANG:

105509848(ISL1)

CJC:	100385297(ISL1)

SBQ:	101043295(ISL1)

CIMI:

108307753(ISL1)

CSYR:

103264925(ISL1)

MMUR:

105857792(ISL1)

LCAT:

123648661(ISL1)

PCOQ:

105819111(ISL1)

OGA:	100941621(ISL1)

MMU:	16392(Isl1)

MCAL:

110308328(Isl1)

MPAH:

110328969(Isl1)

RNO:	64444(Isl1)

MCOC:

116083558(Isl1)

ANU:	117724043(Isl1)

MUN:	110564883(Isl1)

CGE:	100774367(Isl1)

MAUA:

101836649(Isl1)

PROB:

127221167(Isl1)

PLEU:

114703774(Isl1)

MORG:

121455945(Isl1)

MFOT:

126507951

AAMP:

119810671(Isl1)

NGI:	103734040(Isl1)

HGL:	101704803(Isl1)

CPOC:

100728707(Isl1)

CCAN:

109677632(Isl1)

DORD:

105987338(Isl1)

DSP:	122116995(Isl1)

PLOP:

125367646(Isl1)

NCAR:

124987645

MMMA:

107151958(Isl1)

OCU:

100344068

OPI:	101519851(ISL1)

TUP:	102477870(ISL1)

GVR:	103592626(ISL1)

CFA:	612954(ISL1)

CLUD:

112651477(ISL1)

VVP:	112933780(ISL1)

VLG:	121486268(ISL1)

NPO:	129509752(ISL1)

AML:	100475643(ISL1)

UMR:	103664640(ISL1)

UAH:	113260755(ISL1)

UAR:	123785564(ISL1)

ELK:

111141283

LLV:

125100218

MPUF:

101678895(ISL1)

MNP:	132027507(ISL1)

MLK:	131831327(ISL1)

NVS:	122902203(ISL1)

ORO:	101374155(ISL1)

EJU:	114204715(ISL1)

ZCA:	113929546(ISL1)

MLX:	118006637 118006763

NSU:	110586564(ISL1)

LWW:	102729319(ISL1)

FCA:	101090235(ISL1)

PYU:	121044472(ISL1)

PCOO:

112860474(ISL1)

PBG:	122493972(ISL1)

PVIV:

125170325(ISL1)

LRUF:

124507390

PTG:	102956435(ISL1)

PPAD:

109275893(ISL1)

PUC:

125934602

AJU:

106987674

HHV:	120221581(ISL1)

BTA:	614040(ISL1)

BOM:	102277581(ISL1)

BIU:	109574770(ISL1)

BBUB:

102405894(ISL1)

BBIS:

105001079(ISL1)

CHX:	102173232(ISL1)

OAS:	541604(ISL1)

BTAX:

128066212(ISL1)

ODA:	120879235(ISL1)

CCAD:

122454562(ISL1)

MBEZ:

129553272(ISL1)

SSC:	100511417(ISL1)

CFR:	102506556(ISL1)

CBAI:

105077867(ISL1)

CDK:	105084257(ISL1)

VPC:	102545470(ISL1)

BACU:

103013533(ISL1)

BMUS:

118893232(ISL1)

LVE:	103069810(ISL1)

OOR:	101279197(ISL1)

DLE:	111163144(ISL1)

PCAD:

102995645(ISL1)

PSIU:

116751798(ISL1)

NASI:

112396598(ISL1)

ECB:	100052482(ISL1)

EPZ:	103551839(ISL1)

EAI:	106839902(ISL1)

MYB:	102247168(ISL1)

MYD:	102759187(ISL1)

MMYO:

118649650 118656913(ISL1)

MLF:

102419557

PKL:	118703639(ISL1)

EFUS:

103298069(ISL1)

MNA:	107526278(ISL1)

DRO:	112315289(ISL1)

SHON:

118981688(ISL1)

AJM:	119049192(ISL1)

PDIC:

114504661(ISL1)

PHAS:

123819531(ISL1)

MMF:	118642371(ISL1)

PPAM:

129071938(ISL1)

HAI:	109382111(ISL1)

RFQ:	117024468(ISL1)

PALE:

102896694(ISL1)

PGIG:

120608160(ISL1)

PVP:	105301291(ISL1)

RAY:	107509612(ISL1)

MJV:	108396732(ISL1)

TOD:	119260978(ISL1)

SARA:

101547151(ISL1)

SETR:

126001164(ISL1)

LAV:	100664449(ISL1)

TMU:

101347264

ETF:	101651971(ISL1)

DNM:	101414626(ISL1)

MDO:	100016167(ISL1)

GAS:	123231484(ISL1)

SHR:	100927995(ISL1)

AFZ:

127557204

PCW:	110213531(ISL1)

OAA:	114808993(ISL1)

GGA:	396383(ISL1)

PCOC:

116239108(ISL1)

MGP:	104914871(ISL1)

CJO:	107305974(ISL1)

TPAI:

128074359(ISL1)

LMUT:

125686582(ISL1)

NMEL:

110390359(ISL1)

APLA:

101795023(ISL1)

ACYG:

106049604(ISL1)

AFUL:

116500785(ISL1)

TGU:	100231918(ISL1)

LSR:	110483751(ISL1)

SCAN:

103821087(ISL1)

PMOA:

120502409(ISL1)

OTC:	121346625(ISL1)

PRUF:

121365269(ISL1)

GFR:	102038624(ISL1)

FAB:	101817833(ISL1)

OMA:	130264948(ISL1)

PHI:	102106266(ISL1)

PMAJ:

107215787(ISL1)

CCAE:

111941384(ISL1)

CCW:	104686765(ISL1)

CBRC:

103622962(ISL2) 103624032(ISL1)

ETL:	114072651(ISL1)

ZAB:	102072427(ISL1)

SVG:	106857918(ISL1)

MMEA:

130576851(ISL1)

HRT:	120765409(ISL1)

FPG:	101913687(ISL1)

FCH:	102055387(ISL1)

CLV:	102090708(ISL1)

EGZ:	104131631(ISL1)

PCRI:

104026355(ISL1)

PLET:

104622337 104624475

EHS:	104508609(ISL1)

PCAO:

104041308(ISL1)

ACUN:

113489779(ISL1)

TALA:

104364556(ISL1)

PADL:

103919455(ISL1)

AFOR:

103893440(ISL1)

ACHC:

115337285(ISL1) 121232845

HALD:

104314965(ISL1)

HLE:	104829352(ISL1)

AGEN:

126035333 126035997

GCL:	127027663 127028590

CCRI:

104167119(ISL1)

MUI:	104548228(ISL1)

BREG:

104643891(ISL1)

FGA:	104083334(ISL1)

GSTE:

104252644(ISL1)

LDI:	104341637(ISL1)

MNB:	103768727(ISL1)

OHA:	104337777(ISL1)

NNT:	104401035(ISL1)

SHAB:

115601011(ISL1)

DPUB:

104306974(ISL1)

PGUU:

104461110

ACAR:

104519789(ISL1)

CPEA:

104398504(ISL1)

AVIT:

104269425(ISL1)

CVF:	104292232 104294594(ISL1)

RTD:	128902767(ISL1)

CUCA:

104054774(ISL1)

TEO:	104377271(ISL1)

BRHI:

104494355(ISL1)

AAM:	106488108(ISL1)

AROW:

112962179(ISL1)

NPD:	112945232(ISL1)

TGT:	104577199(ISL1)

DNE:	112983995(ISL1)

SCAM:

104146896(ISL1)

ASN:	102377950(ISL1)

AMJ:	102570622(ISL1)

CPOO:

109307892(ISL1)

GGN:	109297836(ISL1)

PSS:	102451726(ISL1)

CMY:	102933994(ISL1) 119564483

CCAY:

125627268 125637165(ISL1)

DCC:	119848524 119855900(ISL1)

CPIC:

101949094(ISL1) 101952089

TST:	117869076 117879608(ISL1)

CABI:

116838560 116839390(ISL1)

MRV:	120391565 120408266(ISL1)

ACS:	100558652(isl1)

ASAO:

132766974(ISL1)

PVT:	110073886(ISL1)

SUND:

121920684(ISL1)

PBI:	103055401(ISL1)

PMUR:

107290967(ISL1)

CTIG:

120313329(ISL1)

TSR:	106556214(ISL1)

PGUT:

117679173(ISL1)

PTEX:

113445229(ISL1)

NSS:	113411331(ISL1)

VKO:	123031531(ISL1)

PMUA:

114606415(ISL1)

PRAF:

128423258(ISL1)

ZVI:	118077286(ISL1) 118077585

HCG:	128341539(ISL1)

GJA:	107108081(ISL1)

STOW:

125436860(ISL1)

EMC:	129334819(ISL1)

XLA:	100126604(isl1.S) 108695787(isl1.L)

NPR:	108797299(ISL1)

RTEM:

120928161(ISL1)

BBUF:

120991338(ISL1)

BGAR:

122936334(ISL1)

MUO:	115462227(ISL1) 115462228 115480930

GSH:	117352638(ISL1) 117352639 117366112

DRE:	30147(isl1a) 415131(isl1b)

SRX:	107708623 107713271 107744147 107746799

SANH:

107661270 107681192(isl1) 107685169 107686487

SGH:	107595574 107599171 107602011

CCAR:

109051964 109061514 109097805

CAUA:

113049137 113077938 113110411

CGIB:

127958405 127966653 128002671

PTET:

122344905(isl1a) 122352596(isl1b)

LROH:

127164872(isl1a) 127172280(isl1b)

OMC:	131541145(isl1a) 131548353(isl1b)

PPRM:

120461867(isl1a) 120481712(isl1b)

RKG:	130087054(isl1b) 130103778(isl1a)

MAMB:

125262872(isl1b) 125267009(isl1a)

CIDE:

127512314 127520907

MASI:

127429693 127431781 127432319 127433218

TROS:

130546000(isl1b) 130571361(isl1a)

TDW:	130411971(isl1b) 130419696(isl1a)

MANU:

129440549(isl1a) 129447344(isl1b)

IPU:	108255333(isl1a) 108277114

IFU:	128599257(isl1a) 128620790

PHYP:

113536945(isl1) 113543999

SMEO:

124380662(isl1a) 124393516

TFD:	113653280(isl1a) 113661352

TVC:	132855243(isl1a) 132863716

AMEX:

103021841 103024036(isl1)

CMAO:

118824657(isl1l) 118827245(isl1)

EEE:	113589758(isl1)

CHAR:

105894586(isl1b) 105901168(isl1a)

TRU:	101068037(isl1)

TFS:	130525805(isl1a)

LCO:	104934528(isl1)

NCC:	104947107(isl1)

TBEN:

117472929(isl1)

CGOB:

115012950

PGEO:

117453101(isl1)

GACU:

117534985(isl1)

EMAC:

134873866(isl1a)

ELY:	117251894(isl1)

EFO:	125890264(isl1a)

PLEP:

121944857(isl1a)

SLUC:

116050432(isl1)

ECRA:

117945268(isl1)

ESP:

116689473

PFLV:

114555324

GAT:	120831272(isl1a)

PPUG:

119225685(isl1)

AFB:	129101676(isl1a)

CLUM:

117736602(isl1)

PSWI:

130196882(isl1a)

MSAM:

119891107(isl1)

SCHU:

122876667(isl1a)

CUD:	121510341(isl1a)

ALAT:

119018916(isl1)

MZE:

101475168

ONL:

100700683

OAU:	116312711(isl1a)

OLA:	101165983(isl1)

OML:	112137682(isl1)

CSAI:

133450778(isl1a)

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122827022(isl1a)

PPRL:

129355330(isl1a)

CVG:

107092429

CTUL:

119789950(isl1)

GMU:	124877372(isl1a)

NFU:

107374027

KMR:	108249569(isl1)

NWH:	119413567(isl1a)

AOCE:

111565140(isl1)

MCEP:

125012937(isl1a)

CSEM:

103396957 103397383(isl1)

POV:	109640154(isl1)

SSEN:

122761384

HHIP:

117767862(isl1)

HSP:	118114581(isl1a)

SMAU:

118314560(isl1a)

LCF:	108898554(isl1a)

SDU:	111230832(isl1)

SLAL:

111647909(isl1)

XGL:	120805442(isl1a)

HCQ:

109510507

SSCV:

125993650

SBIA:

133499390(isl1a)

PEE:	133399523(isl1a)

PTAO:

133484123(isl1a)

BPEC:

110172505(isl1)

MALB:

109959708(isl1)

BSPL:

114846403(isl1a)

SJO:	128365322(isl1a)

SASA:

106570925(isl1) 106595156

STRU:

115165047 115200640(isl1)

OTW:	112237599 112262495(isl1a)

OMY:	110525150(isl1) 110536483

OGO:	124033431 124035326

ONE:	115107400 115125840

OKI:	109882473 109886415(isl1)

OKE:	118376931 118378650 127921311

SALP:

112074764 112076390

SNH:	120042916 120063429(isl1)

CCLU:

121556593(isl1a) 121558661

ELS:	105014555(isl1)

SFM:	108924998 108938061

PKI:	111850008(isl1) 111855113

AANG:

118212366 118226213 118237411(isl1)

LOC:	102693067(isl1)

PSPA:

121299798 121301607 121314132

ARUT:

117403650 117403957 117428852 117966289

PSEX:

120532478(isl1a)

LCM:	102355848 102359600(ISL1)

CMK:	103177842(isl1a)

RTP:	109920259(isl1a)

CPLA:

122549066(isl1a) 122565375

HOC:	132818824(isl1a) 132829210

LERI:

129696217(isl1a) 129711326

PMRN:

116950617 116953548(ISL1)

LRJ:	133354275 133355164 133355166

BFO:

118409463

BBEL:

109466991

CIN:	445793(isl)

SCLV:

SPU:

APLC:

AJC:

SKO:	100303560(isl1)

DME:	Dmel_CG10619(tup)

DER:

6549328

DSE:

6614604

DSI:	Dsimw501_GD21801(Dsim_GD21801)

DYA:	Dyak_GE12696

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI17017

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:	108369521 108376892

AOQ:

129249276

TDA:

119689377

MDE:	101893830 131805959

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

CQU:	CpipJ_CPIJ012632

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:	662583(Tup)

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_206411B

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:

PGW:

CFEL:

CCRN:

API:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:	103504965 103504990

CLEC:

HHAL:

NLU:

HVI:

MQU:

PHU:	Phum_PHUM202210

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:	110855060 110863122

DPX:	DAPPUDRAFT_50562

DMK:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:	126998766 126998768

MNZ:	135195284 135195593

HAZT:

108669590 108682683

EAF:	111695932 111709996

PPOI:

ISC:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

NAI:	NECAME_02202

HRO:	HELRODRAFT_106340 HELRODRAFT_188500 HELRODRAFT_62537 HELRODRAFT_88718

LGI:	LOTGIDRAFT_232365

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:

CANU:

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

OBI:

LAK:

EGL:

NVE:

EPA:

ATEN:

ADF:	107349259(AdiIslet)

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HSY:

TAD:	TRIADDRAFT_30944

AQU:

105312610

GMX:

100815231

» show all

Reference

PMID:14766174

Authors

Thaler JP, Koo SJ, Kania A, Lettieri K, Andrews S, Cox C, Jessell TM, Pfaff SL

Title

A postmitotic role for Isl-class LIM homeodomain proteins in the assignment of visceral spinal motor neuron identity.

Journal

Neuron 41:337-50 (2004)
DOI:10.1016/S0896-6273(04)00011-X

Sequence

[mmu:16392]

All links

Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Gene (1614)   
   KEGG GENES (720)   
   KEGG MGENES (65)   
   RefGene (825)   
   OC (4)   
Literature (1)   
   PubMed (1)   
All databases (1619)   

Download RDF

DBGET integrated database retrieval system