KEGG   ORTHOLOGY: K10351Help
Entry
K10351                      KO                                     

Name
MYL2
Definition
myosin regulatory light chain 2
Pathway
Cardiac muscle contraction
Adrenergic signaling in cardiomyocytes
Apelin signaling pathway
Focal adhesion
Tight junction
Leukocyte transendothelial migration
Regulation of actin cytoskeleton
Hypertrophic cardiomyopathy (HCM)
Dilated cardiomyopathy
Disease
H00292  
Hypertrophic cardiomyopathy (HCM)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04371 Apelin signaling pathway
    K10351  MYL2; myosin regulatory light chain 2
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    K10351  MYL2; myosin regulatory light chain 2
   04530 Tight junction
    K10351  MYL2; myosin regulatory light chain 2
  Cell motility
   04810 Regulation of actin cytoskeleton
    K10351  MYL2; myosin regulatory light chain 2
 Organismal Systems
  Immune system
   04670 Leukocyte transendothelial migration
    K10351  MYL2; myosin regulatory light chain 2
  Circulatory system
   04260 Cardiac muscle contraction
    K10351  MYL2; myosin regulatory light chain 2
   04261 Adrenergic signaling in cardiomyocytes
    K10351  MYL2; myosin regulatory light chain 2
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K10351  MYL2; myosin regulatory light chain 2
   05414 Dilated cardiomyopathy (DCM)
    K10351  MYL2; myosin regulatory light chain 2
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     K10351  MYL2; myosin regulatory light chain 2
BRITE hierarchy
Genes
HSA: 
4633(MYL2)
PTR: 
452243(MYL2)
PPS: 
100973169(MYL2)
GGO: 
101146701(MYL2)
PON: 
100462280(MYL2)
NLE: 
100590389(MYL2)
MCC: 
711937(MYL2)
MCF: 
102147025(MYL2)
CSAB: 
103239122(MYL2)
RRO: 
104674641(MYL2)
CJC: 
100408790(MYL2)
SBQ: 
101050353(MYL2)
MMU: 
17906(Myl2)
RNO: 
363925(Myl2)
CGE: 
100773969(Myl2)
NGI: 
103745580(Myl2)
HGL: 
OCU: 
100353304(MYL2)
TUP: 
102502505(MYL2)
CFA: 
403614(MYL2)
AML: 
100483724(MYL2)
UMR: 
103661279(MYL2)
FCA: 
101101169(MYL2)
PTG: 
102954811(MYL2)
AJU: 
106967527(MYL2)
BTA: 
505519(MYL2)
BOM: 
102275987(MYL2)
PHD: 
CHX: 
102179873(MYL2)
OAS: 
100196904(MYL2)
SSC: 
396690(MYL2)
CFR: 
102509636(MYL2)
BACU: 
103016555(MYL2)
LVE: 
103077775(MYL2)
ECB: 
100147688(MYL2)
MYB: 
102258260(MYL2)
MYD: 
102754925(MYL2)
HAI: 
PALE: 
102888244(MYL2)
MDO: 
100019715(MYL2)
SHR: 
100917142(MYL2)
OAA: 
100074559(MYL2)
GGA: 
416874(MYL2)
MGP: 
100547128(MYL2)
CJO: 
107321507(MYL2) 107322704(MYL10)
APLA: 
TGU: 
100221365(MYL10) 100223766(MYL2)
GFR: 
102032391(MYL2) 102034903(MYL10)
FAB: 
101808099(MYL2) 101816977(MYL10)
PHI: 
102101963(MYL2) 102110780(MYL10)
CCW: 
104688679(MYL2) 104691114(MYL10)
FPG: 
101916533(MYL2) 101923421(MYL10)
FCH: 
102046529(MYL2)
CLV: 
AAM: 
106495672(MYL2) 106497327(MYL10)
ASN: 
102375176(MYL2) 102386379(MYL10)
AMJ: 
102559708(MYL10) 102563829(MYL2)
PSS: 
102449621(MYL2)
CMY: 
CPIC: 
101931587(MYL2)
ACS: 
100566191(myl2)
PBI: 
103055734(MYL2)
GJA: 
107112184(MYL2)
XLA: 
XTR: 
100135705(myl2)
DRE: 
100537244(myl2a) 677750(myl2b)
IPU: 
TRU: 
TNG: 
LCO: 
MZE: 
OLA: 
XMA: 
SASA: 
LCM: 
102362592(MYL2)
CMK: 
103184326(myl2) 103188437(myl10)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Stevens L, Bastide B, Hedou J, Cieniewski-Bernard C, Montel V, Cochon L, Dupont E, Mounier Y
  Title
Potential regulation of human muscle plasticity by MLC2 post-translational modifications during bed rest and countermeasures.
  Journal
Arch Biochem Biophys 540:125-32 (2013)
Reference
PMID:2704627
  Authors
Dalla Libera L, Hoffmann E, Floroff M, Jackowski G
  Title
Isolation and nucleotide sequence of the cDNA encoding human ventricular myosin light chain 2.
  Journal
Nucleic Acids Res 17:2360 (1989)
  Sequence
[hsa:4633]

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