KEGG   ORTHOLOGY: K10591Help
Entry
K10591                      KO                                     
Name
NEDD4, RSP5
Definition
E3 ubiquitin-protein ligase NEDD4 [EC:6.3.2.19]
Pathway
Ubiquitin mediated proteolysis
Endocytosis
Epstein-Barr virus infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K10591  NEDD4, RSP5; E3 ubiquitin-protein ligase NEDD4
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K10591  NEDD4, RSP5; E3 ubiquitin-protein ligase NEDD4
 Human Diseases
  Infectious diseases
   05169 Epstein-Barr virus infection
    K10591  NEDD4, RSP5; E3 ubiquitin-protein ligase NEDD4
Enzymes [BR:ko01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.19  ubiquitin---protein ligase
     K10591  NEDD4, RSP5; E3 ubiquitin-protein ligase NEDD4
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  HECT type E3
   K10591  NEDD4, RSP5; E3 ubiquitin-protein ligase NEDD4
BRITE hierarchy
Genes
HSA: 
4734(NEDD4)
PTR: 
467689(NEDD4)
PPS: 
100969945(NEDD4)
GGO: 
101129022(NEDD4)
PON: 
100457150(NEDD4)
MCC: 
699550(NEDD4)
MMU: 
17999(Nedd4)
RNO: 
25489(Nedd4)
CFA: 
608738(NEDD4)
AML: 
FCA: 
101085214(NEDD4)
BTA: 
507781(NEDD4)
SSC: 
100622318
ECB: 
100054735(NEDD4)
SHR: 
100916239(NEDD4)
OAA: 
100083335(NEDD4)
GGA: 
415406(NEDD4)
MGP: 
100547485(NEDD4)
TGU: 
100223530(NEDD4)
XTR: 
100496333(nedd4)
DRE: 
619412(nedd4a)
OLA: 
101156564
BFO: 
BRAFLDRAFT_113742
CIN: 
100176211(nedd4l)
SPU: 
578960 588926
DME: 
Dmel_CG42279(Nedd4)
DPO: 
Dpse_GA16742
DAN: 
Dana_GF10539
DER: 
Dere_GG13624
DPE: 
Dper_GL11879
DSE: 
Dsec_GM25709
DSI: 
Dsim_GD14716
DWI: 
Dwil_GK17749
DYA: 
Dyak_GE19920
DGR: 
Dgri_GH16118
DMO: 
Dmoj_GI12384
DVI: 
Dvir_GJ12273
AGA: 
AgaP_AGAP000787 AgaP_AGAP003133
AAG: 
AaeL_AAEL002536 AaeL_AAEL008374
CQU: 
CpipJ_CPIJ011781 CpipJ_CPIJ015113
AME: 
411723(Nedd4)
NVI: 
100115069(Nedd4)
TCA: 
663811
API: 
100159671
PHU: 
Phum_PHUM236520
ISC: 
IscW_ISCW021604
CEL: 
CELE_Y92H12A.2(Y92H12A.2)
CBR: 
CBG22256
BMY: 
Bm1_48500
TSP: 
Tsp_05428
NVE: 
NEMVE_v1g161803
HMG: 
100205464
ATH: 
AT4G12570(UPL5)
ALY: 
ARALYDRAFT_490058 ARALYDRAFT_682952 ARALYDRAFT_908808
GMX: 
100789233 100796470 100801584
MTR: 
MTR_2g025830 MTR_2g025930 MTR_4g133120
CSV: 
101212043
RCU: 
RCOM_0401100
POP: 
POPTR_667133 POPTR_761803 POPTR_777225
VVI: 
100244983
OSA: 
4347416
DOSA: 
Os09t0484300-01(Os09g0484300)
BDI: 
100826898 100833092
SBI: 
SORBI_02g028170(SORBIDRAFT_02g028170)
ZMA: 
100279774 100501539
SMO: 
SELMODRAFT_117305(UPL5-1) SELMODRAFT_50844(UPL5-2)
PPP: 
PHYPADRAFT_138593 PHYPADRAFT_143599 PHYPADRAFT_147841
SCE: 
YER125W(RSP5)
AGO: 
AGOS_ADL055C
ERC: 
Ecym_8394
KLA: 
KLLA0E13575g
LTH: 
KLTH0E06908g
PPA: 
PAS_chr2-1_0354
VPO: 
Kpol_1031p39
ZRO: 
ZYRO0G18920g
CGR: 
CAGL0K02255g
NCS: 
NCAS_0B04540(NCAS0B04540)
NDI: 
NDAI_0B02460(NDAI0B02460)
TPF: 
TPHA_0D01030(TPHA0D01030)
TBL: 
TBLA_0G02790(TBLA0G02790)
TDL: 
TDEL_0F00990(TDEL0F00990)
KAF: 
KAFR_0B02100(KAFR0B02100)
DHA: 
DEHA2D03718g
PIC: 
PICST_65602
PGU: 
PGUG_01556
LEL: 
LELG_02410
CAL: 
CaO19.11111(RSP5) CaO19.3628(RSP5)
CTP: 
CTRG_01844
CDU: 
CD36_22630
COT: 
CORT_0C06280
YLI: 
YALI0E18117g
CLU: 
CLUG_02418
NCR: 
NCU03947
SMP: 
SMAC_06117
PAN: 
PODANSg928
TTT: 
THITE_2110805
MTM: 
MYCTH_2307409
MGR: 
MGG_07255
FGR: 
FG10272.1
NHE: 
NECHADRAFT_104408
VAL: 
VDBG_00464
SSL: 
SS1G_03708
BFU: 
BC1G_07055
ANI: 
AN1339.2
NFI: 
NFIA_016110
AFM: 
AFUA_1G09500
AOR: 
AOR_1_1614194(AO090012000923)
ANG: 
ANI_1_154074(An08g01060)
AFV: 
AFLA_021670
ACT: 
ACLA_026000
PCS: 
Pc16g02760
CIM: 
CIMG_07120
CPW: 
CPC735_034550
PBL: 
PAAG_03135
URE: 
UREG_05780
ABE: 
ARB_08026
TVE: 
TRV_04341
AJE: 
HCAG_06159
PNO: 
SNOG_05097
PTE: 
PTT_11143
ZTR: 
MYCGRDRAFT_77175
TML: 
GSTUM_00011744001
SPO: 
SPAC11G7.02(pub1) SPAC1805.15c(pub2) SPBC16E9.11c(pub3)
CNE: 
CNH00220
CNB: 
CNBL0210
CGI: 
CGB_H0270C
LBC: 
LACBIDRAFT_247319 LACBIDRAFT_309180
MPR: 
MPER_06057
CCI: 
CC1G_03837 CC1G_07156
SCM: 
SCHCODRAFT_256070 SCHCODRAFT_81787
UMA: 
UM00663.1
MGL: 
MGL_0607
PGR: 
PGTG_13200
MBR: 
MONBRDRAFT_12860 MONBRDRAFT_29603 MONBRDRAFT_29604
TPS: 
THAPSDRAFT_9570
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Yang B, Kumar S
  Title
Nedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functions.
  Journal
Cell Death Differ 17:68-77 (2010)
Reference
  Authors
Persaud A, Alberts P, Hayes M, Guettler S, Clarke I, Sicheri F, Dirks P, Ciruna B, Rotin D
  Title
Nedd4-1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function.
  Journal
EMBO J 30:3259-73 (2011)
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