KEGG ORTHOLOGY: K10648

ORTHOLOGY: K10648

Entry

K10648                      KO

Symbol

TRIM5

Name

tripartite motif-containing protein 5 [EC:2.3.2.27]

Pathway

map03250

Viral life cycle - HIV-1

map05170

Human immunodeficiency virus 1 infection

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09125 Information processing in viruses
   03250 Viral life cycle - HIV-1
    K10648  TRIM5; tripartite motif-containing protein 5
09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K10648  TRIM5; tripartite motif-containing protein 5
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K10648  TRIM5; tripartite motif-containing protein 5
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     K10648  TRIM5; tripartite motif-containing protein 5
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  Single Ring-finger type E3
   TRIM/RBCC proteins
    K10648  TRIM5; tripartite motif-containing protein 5

Genes

HSA:	85363(TRIM5)

PTR:	503563(TRIM5)

PPS:	100984455(TRIM5)

GGO:	101133340(TRIM5)

PON:	100137088(TRIM5)

NLE:	100589999(TRIM5)

HMH:	116476602(TRIM5)

MCC:	574288(TRIM5)

MCF:	102135840(TRIM5)

MTHB:

126935065

MNI:	105468602(TRIM5)

CSAB:

103247881(TRIM5)

CATY:

105578889(TRIM5)

PANU:

100126714(TRIM5)

TGE:	112605771(TRIM5)

MLEU:

105533500(TRIM5)

RRO:	104663393(TRIM5)

RBB:	108538965(TRIM5)

TFN:	117081694(TRIM5)

PTEH:

111540945(TRIM5)

CANG:

105527301(TRIM5)

CJC:

100385852

SBQ:	101032043(TRIM5)

CIMI:

108288364(TRIM5)

CSYR:

103268948(TRIM5)

MMUR:

105883476

LCAT:

123642337(TRIM5)

PCOQ:

105818435(TRIM5)

OGA:	100963773 105887415

MMU:	209387(Trim30d) 319236(Trim12c) 667823(Trim5)

MCAL:

110289038 110289082 110298013

MPAH:

110314714 110320438(Trim5) 110332715 110336390

RNO:	308906(Trim5) 499223(Trim30d)

MCOC:

116068538 116100758 116102717 116102721 116102722 116104669

ANU:	117695466 117710884(Trim5) 117715734

MUN:	110558329 110558330

CGE:	100752691 100762389 100762680 100771630 100772719 113830641

MAUA:

101822541 101822815 101823081 101823352 101826240 106022651 121144029

PROB:

127228084 127228086 127228090

PLEU:

114686891 114686894 114686895 114686898 119086094

MORG:

121457301 121457812 121457890 121458122 121458131

MFOT:

126492635 126492636 126492638 126492642 126492678 126514416

AAMP:

119810418 119819822 119821348 119821581 119825440

NGI:	103732077 103732120 103732121

HGL:	101716219(Trim5) 101721041

CPOC:

100714924 100715495 100716056

DORD:

106000347 106000348 106000349 106002440

DSP:	122114846 122114953 122114980 122114988

PLOP:

125362393 125362715 125362716

NCAR:

124958138

MMMA:

107135589 107157382

OCU:	100126072(TRIM5)

OPI:

101532545

TUP:	102473181 102478391(TRIM5) 102488769 102489998

GVR:	103581138 103605871 103609157

UMR:

UAH:

UAR:

LLV:

MPUF:

MNP:

ORO:

MLX:

NSU:

FCA:	100302544(TRIM5)

PCOO:

PBG:

PVIV:

LRUF:

PTG:	102971923(TRIM34)

HHV:

120225598

BTA:	516599 616948 786870

BOM:	102273840 102280864 102281146 102281509 102283392

BIU:	109563642 109569681 109569825

BBUB:

102393893

BBIS:

104991286 104991954 105003320 105003391

CHX:	102169889 102170165 102173185 102179935 108637671

OAS:	101119159 105614607 114118416

BTAX:

128060077 128060113

ODA:	120859842 120860663 120876597 120876602

CCAD:

MBEZ:

SSC:

CFR:

CBAI:

CDK:

ECB:	100054534 100069440 102149883 106780875

EPZ:	103553684 103554374 103565910

EAI:	106830178 106830220 106830222 106830229

MYB:	102251491 102256215 102259214 102262635

MYD:	102752970(TRIM5) 102753236 102753792 102772702

MMYO:

118664400 118664739 118664744 118664747 118664748

MLF:	102431987 102437606 106694372 111822979 111827152

PKL:

118713480

EFUS:

103303437 103303439 103303470 103304829

MNA:	107538608 107538665 107540508

DRO:	112317577 112317581 112317583 112317586

SHON:

118975708 118981016 118990796

AJM:	119050146 119055626

PDIC:

114500409

PHAS:

123819199 123819202 123819206 123819250

MMF:	118625157 118627563 118628341 118628343 118628345

PPAM:

129076394 129076396 129076447

HAI:	109378611 109396555

PALE:

102888261

PGIG:

120590256

PVP:

105307601

RAY:	107501120 107513410

MJV:

108385131

TOD:	119254978 119254980 119255566 119255567 119255571

SARA:

101539913

LAV:	100666123 100666406 100674587 100674877

ETF:

101662635

» show all

Reference

PMID:18248090

Authors

Uchil PD, Quinlan BD, Chan WT, Luna JM, Mothes W

Title

TRIM E3 ligases interfere with early and late stages of the retroviral life cycle.

Journal

PLoS Pathog 4:e16 (2008)
DOI:10.1371/journal.ppat.0040016

Sequence

[hsa:85363]

Reference

PMID:16401428

Authors

Sawyer SL, Wu LI, Akey JM, Emerman M, Malik HS

Title

High-frequency persistence of an impaired allele of the retroviral defense gene TRIM5alpha in humans.

Journal

Curr Biol 16:95-100 (2006)
DOI:10.1016/j.cub.2005.11.045

Sequence

[hsa:85363]

All links

Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (258)   
   KEGG GENES (253)   
   RefGene (2)   
   OC (3)   
Literature (2)   
   PubMed (2)   
All databases (268)   

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