KEGG   ORTHOLOGY: K10741Help
Entry
K10741                      KO                                     
Name
RPA4
Definition
replication factor A4
Pathway
DNA replication
Nucleotide excision repair
Mismatch repair
Homologous recombination
Fanconi anemia pathway
Module
M00288  
RPA complex
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Replication and repair
   03030 DNA replication
    K10741  RPA4; replication factor A4
   03420 Nucleotide excision repair
    K10741  RPA4; replication factor A4
   03430 Mismatch repair
    K10741  RPA4; replication factor A4
   03440 Homologous recombination
    K10741  RPA4; replication factor A4
   03460 Fanconi anemia pathway
    K10741  RPA4; replication factor A4
KEGG pathway modules [BR:ko00002]
 Structural complex
  Genetic information processing
   Replication system
    M00288  RPA complex [BR:ko03032 ko03400]
     K10741  RPA4; replication factor A4
DNA replication proteins [BR:ko03032]
 Eukaryotic Type
  DNA Replication Elongation Factors
   RPA (replication factor A)
    K10741  RPA4; replication factor A4
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    RPA (replication factor A)
     K10741  RPA4; replication factor A4
   MMR (mismatch exicision repair)
    RPA (replication factor A)
     K10741  RPA4; replication factor A4
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    RPA (replication factor A)
     K10741  RPA4; replication factor A4
BRITE hierarchy
Genes
HSA: 
29935(RPA4)
PTR: 
736976(RPA4)
PPS: 
100982694(RPA4)
GGO: 
101152426(RPA4)
PON: 
100459880(RPA4)
MCC: 
699274(RPA4)
AML: 
ECB: 
TaxonomyKoalaUniProt
Reference
PMID:8087839
  Authors
Stillman B.
  Title
Smart machines at the DNA replication fork.
  Journal
Cell 78:725-8 (1994)
Reference
  Authors
Zou Y, Liu Y, Wu X, Shell SM.
  Title
Functions of human replication protein A (RPA): from DNA replication to DNA damage and stress responses.
  Journal
J Cell Physiol 208:267-73 (2006)
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