| Entry |
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| Name |
MRE11
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| Definition |
double-strand break repair protein MRE11
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| Pathway |
| Homologous recombination | | Non-homologous end-joining |
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| Module |
| MRN complex | | MRX complex | | BRCA1-associated genome surveillance complex (BASC) |
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| Disease |
| DNA repair defects | | Ataxia with ocular apraxia (AOA) |
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| Brite |
KEGG Orthology (KO) [BR:ko00001]
Genetic Information Processing
Replication and repair
03440 Homologous recombination
K10865 MRE11; double-strand break repair protein MRE11
03450 Non-homologous end-joining
K10865 MRE11; double-strand break repair protein MRE11
KEGG pathway modules [BR:ko00002]
Structural complex
Genetic information processing
Repair system
M00291 MRN complex [BR:ko03032 ko03400]
K10865 MRE11; double-strand break repair protein MRE11
M00292 MRX complex [BR:ko03400]
K10865 MRE11; double-strand break repair protein MRE11
M00295 BRCA1-associated genome surveillance complex (BASC) [BR:ko03400]
K10865 MRE11; double-strand break repair protein MRE11
DNA replication proteins [BR:ko03032]
Eukaryotic Type
DNA Replication Termination Factors
Other telomere regulation proteins
MRN complex
K10865 MRE11; double-strand break repair protein MRE11
DNA repair and recombination proteins [BR:ko03400]
Eukaryotic Type
DSBR (double strand breaks repair)
HR (homologous recombination)
MRN(MRX) complex
K10865 MRE11; double-strand break repair protein MRE11
NHEJ (non-homologous end-joining)
MRX complex
K10865 MRE11; double-strand break repair protein MRE11
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| Other DBs |
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| Genes |
HSA: | | PTR: | | PPS: | | GGO: | | PON: | | MCC: | | MMU: | | RNO: | | CFA: | | AML: | | FCA: | | BTA: | | SSC: | | ECB: | | MDO: | | SHR: | | OAA: | | GGA: | | MGP: | | TGU: | | ACS: | | XLA: | | XTR: | | DRE: | | TRU: | | OLA: | | BFO: | | CIN: | | SPU: | | DME: | | DPO: | | DAN: | | DER: | | DPE: | | DSE: | | DSI: | | DWI: | | DYA: | | DGR: | | DMO: | | DVI: | | AGA: | | AAG: | | CQU: | | AME: | | NVI: | | TCA: | | PHU: | | CEL: | | CBR: | | BMY: | | TSP: | | SMM: | | NVE: | | HMG: | | TAD: | | AQU: | | ATH: | | ALY: | | GMX: | | MTR: | | CSV: | | RCU: | | POP: | | VVI: | | OSA: | | DOSA: | | BDI: | | SBI: | | ZMA: | | SMO: | | PPP: | | CRE: | | VCN: | | OLU: | | OTA: | | CME: | | SCE: | | AGO: | | ERC: | | KLA: | | LTH: | | PPA: | | VPO: | | ZRO: | | CGR: | | NCS: | | NDI: | | TPF: | | TBL: | | TDL: | | KAF: | | DHA: | | PIC: | | PGU: | | LEL: | | CAL: | | CTP: | | CDU: | | COT: | | YLI: | | CLU: | | NCR: | | SMP: | | PAN: | | TTT: | | MTM: | | MGR: | | FGR: | | NHE: | | VAL: | | SSL: | | ANI: | | NFI: | | AFM: | | AOR: | | ANG: | | AFV: | | ACT: | | PCS: | | CIM: | | CPW: | | PBL: | | URE: | | ABE: | | TVE: | | AJE: | | PNO: | | PTE: | | ZTR: | | TML: | | SPO: | | CNE: | | CNB: | | CGI: | | LBC: | | MPR: | | CCI: | | SCM: | | UMA: | | MGL: | | PGR: | | ECU: | | EIN: | | EHE: | | NCE: | | MBR: | | NGR: | | DDI: | | DPP: | | EHI: | | EDI: | | PFH: | | PYO: | | PCB: | | PKN: | | PVX: | | PCY: | | TAN: | | TPV: | | BBO: | | CPV: | | CHO: | | TGO: | | TET: | | PTM: | | TBR: | | TCR: | | LIF: | | LDO: | | LMI: | | LBZ: | | GLA: | | TVA: | | PTI: | | TPS: | | PIF: | |
» show all
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| Reference |
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| Authors |
Lee JH, Paull TT |
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| Title |
Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex. |
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| Journal |
Science 304:93-6 (2004) |
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| Reference |
|
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| Authors |
Paull TT, Gellert M |
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| Title |
The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks. |
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| Journal |
Mol Cell 1:969-79 (1998) |
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