KEGG   ORTHOLOGY: K10867Help
Entry
K10867                      KO                                     

Name
NBN, NBS1
Definition
nijmegen breakage syndrome protein 1
Pathway
Homologous recombination
Module
M00291  
MRN complex
M00295  
BRCA1-associated genome surveillance complex (BASC)
Disease
H00094  
Immunodeficiency associated with DNA repair defects
H01344  
Nijmegen Breakage Syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Replication and repair
   03440 Homologous recombination
    K10867  NBN, NBS1; nijmegen breakage syndrome protein 1
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   Repair system
    M00291  MRN complex
     K10867  NBN, NBS1; nijmegen breakage syndrome protein 1
    M00295  BRCA1-associated genome surveillance complex (BASC)
     K10867  NBN, NBS1; nijmegen breakage syndrome protein 1
DNA replication proteins [BR:ko03032]
 Eukaryotic Type
  DNA Replication Termination Factors
   Other telomere regulation proteins
    MRN complex
     K10867  NBN, NBS1; nijmegen breakage syndrome protein 1
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  DSBR (double strand breaks repair)
   HR (homologous recombination)
    MRN(MRX) complex
     K10867  NBN, NBS1; nijmegen breakage syndrome protein 1
BRITE hierarchy
Genes
HSA: 
4683(NBN)
PTR: 
464278(NBN)
PPS: 
GGO: 
PON: 
NLE: 
MCC: 
695912(NBN)
MCF: 
CJC: 
MMU: 
27354(Nbn)
RNO: 
85482(Nbn)
CGE: 
NGI: 
HGL: 
OCU: 
TUP: 
CFA: 
611315(NBN)
AML: 
UMR: 
FCA: 
PTG: 
BTA: 
522943(NBN)
BOM: 
PHD: 
CHX: 
OAS: 
SSC: 
CFR: 
BACU: 
LVE: 
ECB: 
MYB: 
MYD: 
PALE: 
MDO: 
SHR: 
OAA: 
GGA: 
374246(NBN)
MGP: 
APLA: 
TGU: 
FAB: 
PHI: 
FPG: 
FCH: 
CLV: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
XLA: 
403373(nbn)
XTR: 
733826(nbn)
DRE: 
544655(nbn)
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
CIN: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
NVI: 
TCA: 
API: 
PHU: 
ISC: 
LGI: 
SMM: 
NVE: 
HMG: 
TAD: 
ATH: 
AT3G02680(NBS1)
ALY: 
CRB: 
EUS: 
BRP: 
CIT: 
CIC: 
TCC: 
GMX: 
PVU: 
MTR: 
CAM: 
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
CMO: 
RCU: 
POP: 
POPTR_0015s12710g(POPTRDRAFT_575864)
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os10t0487300-01(Os10g0487300)
OBR: 
BDI: 
SBI: 
SORBI_01g018820(SORBIDRAFT_01g018820)
ZMA: 
SITA: 
PDA: 
MUS: 
ATR: 
s00029p00048890(AMTR_s00029p00048890)
SMO: 
PPP: 
CCP: 
FGR: 
FPU: 
NHE: 
SSL: 
ACAN: 
TET: 
PIF: 
PSOJ: 
EHX: 
TVA: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Stiff T, Reis C, Alderton GK, Woodbine L, O'Driscoll M, Jeggo PA
  Title
Nbs1 is required for ATR-dependent phosphorylation events.
  Journal
EMBO J 24:199-208 (2005)
  Sequence
[hsa:4683]

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