KEGG ORTHOLOGY: K10951

ORTHOLOGY: K10951

Entry

K10951                      KO

Symbol

SLC12A2, NKCC1

Name

solute carrier family 12 (sodium/potassium/chloride transporter), member 2

Pathway

map04970

Salivary secretion

map04972

Pancreatic secretion

map05110

Vibrio cholerae infection

Disease

H00604

Deafness, autosomal dominant

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09154 Digestive system
   04970 Salivary secretion
    K10951  SLC12A2, NKCC1; solute carrier family 12 (sodium/potassium/chloride transporter), member 2
   04972 Pancreatic secretion
    K10951  SLC12A2, NKCC1; solute carrier family 12 (sodium/potassium/chloride transporter), member 2
09160 Human Diseases
  09171 Infectious disease: bacterial
   05110 Vibrio cholerae infection
    K10951  SLC12A2, NKCC1; solute carrier family 12 (sodium/potassium/chloride transporter), member 2
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K10951  SLC12A2, NKCC1; solute carrier family 12 (sodium/potassium/chloride transporter), member 2
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K10951  SLC12A2, NKCC1; solute carrier family 12 (sodium/potassium/chloride transporter), member 2
Protein phosphatases and associated proteins [BR:ko01009]
Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K10951  SLC12A2, NKCC1; solute carrier family 12 (sodium/potassium/chloride transporter), member 2
Transporters [BR:ko02000]
Solute carrier family (SLC)
  SLC12: Electroneutral cation-coupled Cl cotransporter
   K10951  SLC12A2, NKCC1; solute carrier family 12 (sodium/potassium/chloride transporter), member 2

Other DBs

GO:

0008511

TC:	2.A.30.1.4 2.A.30.1.5 2.A.30.1.8

Genes

HSA:	6558(SLC12A2)

PTR:	471620(SLC12A2)

PPS:	100978438(SLC12A2)

GGO:	101154445(SLC12A2)

PON:	100435387(SLC12A2)

NLE:	100587696(SLC12A2)

HMH:	116470865(SLC12A2)

MCC:	704672(SLC12A2)

MCF:	101865866(SLC12A2)

MTHB:

126957641

MNI:	105467228(SLC12A2)

CSAB:

103244467(SLC12A2)

CATY:

105599708(SLC12A2)

PANU:

101027028(SLC12A2)

TGE:	112625936(SLC12A2)

MLEU:

105540545(SLC12A2)

RRO:	104659749(SLC12A2)

RBB:	108533166(SLC12A2)

TFN:	117065923(SLC12A2)

PTEH:

111529894(SLC12A2)

CANG:

105511883(SLC12A2)

CJC:	100393963(SLC12A2)

SBQ:	101043035(SLC12A2)

CIMI:

108284306(SLC12A2)

CSYR:

103271323(SLC12A2)

MMUR:

105857747(SLC12A2)

LCAT:

123648625(SLC12A2)

PCOQ:

105810969(SLC12A2)

OGA:	100950465(SLC12A2)

MMU:	20496(Slc12a2)

MCAL:

110284787(Slc12a2)

MPAH:

110332959(Slc12a2)

RNO:	83629(Slc12a2)

MCOC:

116087194(Slc12a2)

ANU:	117719578(Slc12a2)

MUN:	110546924(Slc12a2)

CGE:	100769027(Slc12a2)

MAUA:

101842599(Slc12a2)

PROB:

127234224(Slc12a2)

PLEU:

114708374(Slc12a2)

MORG:

121440614 121443617

MFOT:

126487862

AAMP:

119814382(Slc12a2)

NGI:	103740298(Slc12a2)

HGL:	101705564(Slc12a2)

CPOC:

100714607(Slc12a2)

CCAN:

109702164(Slc12a2)

DORD:

105985123(Slc12a2)

DSP:	122103678(Slc12a2)

PLOP:

125359988(Slc12a2)

NCAR:

124987533

MMMA:

107155050(Slc12a2)

OCU:	100328591 127485219

OPI:	101533178(SLC12A2)

TUP:	102489962(SLC12A2)

GVR:	103589058(SLC12A2)

CFA:	481490(SLC12A2)

CLUD:

112650544(SLC12A2)

VVP:	112917101(SLC12A2)

VLG:	121494408(SLC12A2)

NPO:	129494872(SLC12A2)

AML:	100464321(SLC12A2)

UMR:	103670575(SLC12A2)

UAH:	113261680(SLC12A2)

UAR:	123790392(SLC12A2)

ELK:

111140904

LLV:

125099697

MPUF:

101676823(SLC12A2)

MNP:	132028482(SLC12A2)

MLK:	131831991(SLC12A2)

NVS:	122892178(SLC12A2)

ORO:	101368776(SLC12A2)

EJU:	114209433(SLC12A2)

ZCA:	113928728(SLC12A2)

MLX:	118016595(SLC12A2)

NSU:	110591279(SLC12A2)

LWW:	102736213(SLC12A2)

FCA:	101090325(SLC12A2)

PYU:	121010647(SLC12A2)

PCOO:

112860687(SLC12A2)

PBG:	122486999(SLC12A2)

PVIV:

125160686(SLC12A2)

LRUF:

124515330

PTG:	102958272(SLC12A2)

PPAD:

109250920(SLC12A2)

PUC:

125934862

AJU:

106970727

HHV:	120234736(SLC12A2)

BTA:	286845(SLC12A2)

BOM:	102266898(SLC12A2)

BIU:	109561838(SLC12A2)

BBUB:

102406058(SLC12A2)

BBIS:

104993204(SLC12A2)

CHX:	102173836(SLC12A2)

OAS:	101105242(SLC12A2)

BTAX:

128050660(SLC12A2)

ODA:	120864720(SLC12A2)

CCAD:

122440121(SLC12A2)

MBEZ:

129558061(SLC12A2)

SSC:	100516960(SLC12A2)

CFR:	102514596(SLC12A2)

CBAI:

105082082(SLC12A2)

CDK:	105089862(SLC12A2)

VPC:	102529528(SLC12A2)

BACU:

103018624(SLC12A2)

BMUS:

118892440(SLC12A2)

LVE:	103086086(SLC12A2)

OOR:	101281929(SLC12A2)

DLE:	111182386(SLC12A2)

PCAD:

102991629(SLC12A2)

PSIU:

116751805(SLC12A2)

NASI:

112407762(SLC12A2)

ECB:	100073036(SLC12A2)

EPZ:	103557517(SLC12A2)

EAI:	106842804(SLC12A2)

MYB:	102245247(SLC12A2)

MYD:	102751614(SLC12A2)

MMYO:

118657031(SLC12A2)

MLF:	102438553(SLC12A2)

PKL:	118702700(SLC12A2)

EFUS:

103285954(SLC12A2)

MNA:	107540912(SLC12A2)

DRO:	112314975(SLC12A2)

SHON:

118974873(SLC12A2)

AJM:	119043992(SLC12A2)

PDIC:

114512374(SLC12A2)

PHAS:

123818082(SLC12A2)

MMF:	118641926(SLC12A2)

PPAM:

129083858(SLC12A2)

HAI:	109379070(SLC12A2)

RFQ:	117024716(SLC12A2)

PALE:

102895925(SLC12A2)

PGIG:

120590916(SLC12A2)

PVP:	105290891(SLC12A2)

RAY:	107517865(SLC12A2)

MJV:	108399131(SLC12A2)

TOD:	119243516(SLC12A2)

SARA:

101548929(SLC12A2)

SETR:

126027717(SLC12A2)

LAV:	100653894(SLC12A2)

TMU:

101342027

ETF:	101653083(SLC12A2)

DNM:	101411063(SLC12A2)

MDO:	100022720(SLC12A2)

GAS:	123250913(SLC12A2)

SHR:	100913495(SLC12A2)

AFZ:

127562529

PCW:	110223814(SLC12A2)

GGA:	427123(SLC12A2)

PCOC:

116238201(SLC12A2)

MGP:	104915239(SLC12A2)

CJO:	107306466(SLC12A2)

TPAI:

128089540(SLC12A2)

LMUT:

125686737(SLC12A2)

NMEL:

110389550(SLC12A2)

APLA:

101799181(SLC12A2)

ACYG:

106045237(SLC12A2)

CATA:

118259673(SLC12A2)

AFUL:

116501103(SLC12A2)

TGU:	100230871(SLC12A2)

LSR:	110482553(SLC12A2)

SCAN:

103823238(SLC12A2)

PMOA:

120501790(SLC12A2)

OTC:	121335722(SLC12A2)

PRUF:

121351860(SLC12A2)

GFR:	102038932(SLC12A2)

FAB:	101807057(SLC12A2)

OMA:	130265085(SLC12A2)

PHI:	102109981(SLC12A2)

PMAJ:

107216403(SLC12A2)

CCAE:

111941857(SLC12A2)

CCW:	104691975(SLC12A2)

CBRC:

103616472(SLC12A2)

ETL:	114063868(SLC12A2)

ZAB:	102060519(SLC12A2)

ACHL:

103802665(SLC12A2)

SVG:	106862715(SLC12A2)

MMEA:

130580624(SLC12A2)

HRT:	120765126(SLC12A2)

FPG:	101920614(SLC12A2)

FCH:	102048881(SLC12A2)

CLV:	102094035(SLC12A2)

EGZ:	104125072(SLC12A2)

NNI:	104022596(SLC12A2)

PCRI:

104032138(SLC12A2)

EHS:

104516837

PCAO:

104053893(SLC12A2)

ACUN:

113489940(SLC12A2)

TALA:

104359810(SLC12A2)

PADL:

103913221(SLC12A2)

AFOR:

103898279(SLC12A2)

ACHC:

115336594(SLC12A2) 121232943

HLE:	104830883(SLC12A2)

AGEN:

126035438 126036534

GCL:	127027159 127028152

CCRI:

104162456(SLC12A2)

BREG:

104637811(SLC12A2)

FGA:	104083655(SLC12A2)

LDI:	104345067(SLC12A2)

MNB:

103775909

OHA:	104330003(SLC12A2)

NNT:	104399539(SLC12A2)

SHAB:

115601358(SLC12A2)

DPUB:

104300979(SLC12A2)

CPEA:

104389205(SLC12A2)

AVIT:

104277598(SLC12A2)

CVF:	104290604(SLC12A2)

RTD:	128902163(SLC12A2)

CUCA:

104062641(SLC12A2)

TEO:	104370451(SLC12A2)

BRHI:

104501481(SLC12A2)

AROW:

112961624(SLC12A2)

NPD:	112953508(SLC12A2)

TGT:	104577866(SLC12A2)

DNE:	112992374(SLC12A2)

SCAM:

104150302(SLC12A2)

ASN:	102367935(SLC12A2)

AMJ:	102577309(SLC12A2)

CPOO:

109323466(SLC12A2)

GGN:	109298043(SLC12A2)

PSS:	102450809(SLC12A2)

CMY:	102942372(SLC12A2)

CCAY:

125636770(SLC12A2)

DCC:	119855812(SLC12A2)

CPIC:

101940224(SLC12A2)

TST:	117879628(SLC12A2)

CABI:

116835599(SLC12A2)

MRV:	120408033(SLC12A2)

ACS:	100555453(slc12a2)

ASAO:

132767257(SLC12A2)

PVT:	110077528(SLC12A2)

SUND:

121922384(SLC12A2)

PBI:	103059397(SLC12A2)

PMUR:

107292308(SLC12A2)

CTIG:

120304052(SLC12A2)

TSR:	106545467(SLC12A2)

PGUT:

117661328(SLC12A2)

APRI:

131190962(SLC12A2)

PTEX:

113438531(SLC12A2)

NSS:	113416176(SLC12A2)

VKO:	123031369(SLC12A2)

PMUA:

114606193(SLC12A2)

PRAF:

128422995(SLC12A2)

ZVI:	118076753(SLC12A2)

HCG:	128344083(SLC12A2)

GJA:	107105772(SLC12A2)

STOW:

125436989(SLC12A2)

EMC:	129334325(SLC12A2)

XLA:	100141486(slc12a2.L) 108707193(slc12a2.S)

XTR:	100038244(slc12a2)

NPR:	108795881(SLC12A2)

RTEM:

120932458(SLC12A2)

BBUF:

120988485(SLC12A2)

BGAR:

122924603(SLC12A2)

MUO:	115463245(SLC12A2)

GSH:	117352523(SLC12A2)

DRE:	100329477 100537771 415170(slc12a2)

SRX:	107712558 107726215 107754974

SANH:

107669784 107673756 107680742 107697601

SGH:	107565843 107572516 107573338 107574329(slc12a2)

CCAR:

109049253(slc12a2) 109083255

CAUA:

113052628 113053948 113082901 113109500

CGIB:

127959026 127966176 128019063 128021566

PTET:

122350421 122352787(slc12a2)

LROH:

127162559(slc12a2) 127169734(slc12a2l)

OMC:	131545620(slc12a2l) 131548786(slc12a2)

PPRM:

120463748 120473781(slc12a2)

RKG:	130076714 130099736(slc12a2)

MAMB:

125255271(slc12a2) 125279518

CIDE:

127517368 127520559

MASI:

127414547 127423841 127432444 127433364

TROS:

130545702(slc12a2) 130567573

TDW:	130411301(slc12a2) 130440008

MANU:

129414722 129446080(slc12a2)

IPU:	108265961 108277086

IFU:	128607800 128619981(slc12a2)

PHYP:

113529044 113543507(slc12a2)

SMEO:

124393847(slc12a2) 124399762

TFD:	113655893 113660269(slc12a2)

TVC:	132853820 132863174(slc12a2)

AMEX:

103036479(slc12a2) 103037139

CMAO:

118813256 118824425(slc12a2)

EEE:	113570985 113581174

CHAR:

105890695 105912550(slc12a2)

TRU:	101069002 101074482(slc12a2)

TFS:	130516756(slc12a2) 130526211

TNG:	GSTEN00004595G001 GSTEN00031033G001

LCO:	104934742 104934760

NCC:

104949496

TBEN:

117473026 117473209 117478805(slc12a2)

CGOB:

115014098 115016977

PGEO:

117452556 117455800(slc12a2)

GACU:

117536919(slc12a2) 117555392

EMAC:

134868101(slc12a2) 134873836

ELY:	117253077 117269707(slc12a2)

EFO:	125890816 125905788(slc12a2)

PLEP:

121944785 121959654(slc12a2)

SLUC:

116038153(slc12a2) 116054393

ECRA:

117944391 117959439(slc12a2)

ESP:	116677603 116689051

PFLV:

114555100 114570479(slc12a2)

GAT:	120830145 120831533(slc12a2)

PPUG:

119224820 119226438(slc12a2)

AFB:	129101763 129102694(slc12a2)

CLUM:

117736109 117740268(slc12a2)

PSWI:

130197104 130204891(slc12a2)

MSAM:

119891871 119914120(slc12a2)

SCHU:

122865247(slc12a2) 122876597

CUD:	121510067 121524966(slc12a2)

ALAT:

119020171 119029743(slc12a2)

MZE:	101465564 101484039

ONL:	100694941 100704048

OAU:	116313570 116329323(slc12a2)

OLA:	101167091(slc12a2) 101171840

OML:	112137712 112144156(slc12a2)

CSAI:

133451341(slc12a2l) 133455468(slc12a2)

XMA:	102220288(slc12a2) 102220392

XCO:	114150241(slc12a2) 114154761

XHE:	116723823(slc12a2) 116730101

PRET:

103470831 103473108(slc12a2)

PFOR:

103132022 103152629

PLAI:

106941864 106962440

PMEI:

106911751 106918994

GAF:	122819682(slc12a2) 122828533

PPRL:

129355341(slc12a2) 129366069

CVG:	107104866(slc12a2)

CTUL:

119773746(slc12a2) 119784864

GMU:	124872343 124877975

NFU:	107386185 107390268(slc12a2)

KMR:	108242812 108246461(slc12a2)

ALIM:

106521889 106522216(slc12a2)

NWH:	119413166 119425181(slc12a2)

AOCE:

111570358 111571178

MCEP:

124996950(slc12a2) 125012318

CSEM:

103389632(slc12a2) 103397992 103398932

POV:	109626194(slc12a2)

SSEN:

122758153(slc12a2) 122768965

HHIP:

117768443 117771878(slc12a2)

HSP:	118114669 118125505(slc12a2)

SMAU:

118300651(slc12a2) 118314347

LCF:	108880338 108881529 108881660

SDU:	111221215(slc12a2) 111238553

SLAL:

111645695 111648073(slc12a2)

XGL:	120787517(slc12a2) 120805126

HCQ:	109511667(slc12a2) 109524644

SSCV:

125979873 125993976

SBIA:

133499544 133515221(slc12a2)

PEE:	133400139 133413665(slc12a2)

PTAO:

133465320(slc12a2) 133475723

BPEC:

110161613(slc12a2) 110175642

MALB:

109957334 109970915(slc12a2)

BSPL:

114861703 114866406(slc12a2)

SJO:	128365448 128380255(slc12a2)

SASA:

100136908(nkcc1a) 106562900 106587038

STRU:

115160041(slc12a2) 115167643 115203784

OTW:	112220018(slc12a2) 112230735 112248940

OMY:	110509541 110523207(slc12a2) 110526133

OGO:	123989457(slc12a2) 124016644 124033972

ONE:	115112013 115118556(slc12a2) 115147125

OKI:	109868314(slc12a2) 109875911 109884529

OKE:	118385562 118387287(slc12a2) 118393615

SALP:

111961912(slc12a2) 111963819 111975012

SNH:	120021256 120025473(slc12a2) 120055684

CCLU:

121541403 121582013(slc12a2) 121584614

ELS:	105021758(slc12a2) 105025383

SFM:	108929915(slc12a2)

PKI:	111861023(slc12a2)

AANG:

118206931

LOC:	102695444(slc12a2)

PSPA:

121302315 121315607

ARUT:

117408902 117409660

PSEX:

120532966(slc12a2)

LCM:	102345349(SLC12A2) 102360278

CMK:	103178048(slc12a2)

RTP:	109935221(slc12a2)

CPLA:

122563875(slc12a2)

HOC:	132825783(slc12a2)

LERI:

129695672(slc12a2)

PMRN:

116937805 116950729(SLC12A2)

LRJ:

BFO:

BBEL:

CIN:

SPU:	577708(SLC12A2)

LPIC:

129262307

AJC:

117110245

SKO:	102802928 102808001

DME:	Dmel_CG31547(NKCC) Dmel_CG4357(Ncc69)

DER:	6545030 6552206

DSE:	6605431 6613955

DSI:	Dsimw501_GD12726(Dsim_GD12726) Dsimw501_GD19613(Dsim_GD19613)

DYA:	Dyak_GE20127 Dyak_GE25275

DAN:	6500488 6507612

DSR:	110176286 110177129

DPO:	4802434 4812996

DPE:	6591342 6596154

DMN:	108152995 108156501

DWI:	6645225 6651461

DGR:	6556910 6563893

DMO:	Dmoj_GI12335 Dmoj_GI24495

DAZ:	108613741 108620722

DNV:	108651600 108655997

DHE:	111598711 111603553

DVI:	6622220 6630673

CCAT:

101453385 101456269

BOD:	106616578 106618079

BDR:	105224893 105225976

RZE:	108354025 108360022 108372564

AOQ:	129236045 129241774

TDA:	119667599 119672519 119681071 119684170

MDE:	101888630 101898146

SCAC:

106086244 106091665

LCQ:	111677703 111680159

LSQ:	119606119 119607890

GFS:	119642641 119643699

ECOE:

129938415 129948371

CLON:

129608143 129614015

HIS:	119648291 119660604

AGA:	1269177 1281611 5667478

ACOZ:

120948703 120961013 120961014

AARA:

120897194 120898025 120908400

AMER:

121590474 121590750 121590751

ASTE:

118502777 118502778 118505695

AFUN:

125764430 125764431 125764932

AMOU:

128296921 128297893 128310314

AALI:

118461594 118461609

AAG:	5567586 5572566 5572568

AALB:

109416416 109424025 109430358 109430359 115266041

CQU:	CpipJ_CPIJ007504 CpipJ_CPIJ007505 CpipJ_CPIJ016680 CpipJ_CPIJ019752

CPII:

120413077 120413753 120413777

CNS:	116341070 116350948

BCOO:

119068865 119070100

AME:	409208 409715

ACER:

108004054 108004236

ALAB:

122712199 122721096

ADR:	102670844 102677481

AFLR:

100866055 100869712

BIM:	100741348 100746401

BBIF:

117208274 117216311

BVK:	117233507 117236001

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:	122529350 122535549

CCAL:

108623127 108628220 108632552

OBB:	114875484 114881074

OLG:	117605568 117610873

MGEN:

117219752 117220521

NMEA:

116428527 116430814

CGIG:

122396004 122404486

SOC:	105196993 105204074

MPHA:

105834947 105836941

AEC:	105152024 105153635

ACEP:

105618521 105624720

PBAR:

105422007 105427903

VEM:	105561036 105568528

HST:	105182005 105187054

DQU:	106744266 106746094

CFO:	105249646 105258406

FEX:	115233328 115241328

LHU:	105669100 105675372

PGC:	109854661 109854681

OBO:	105281838 105282354

PCF:	106786402 106793271

PFUC:

122521154 122524432

VPS:	122627110 122629035

VCRB:

124423468 124425222

VVE:	124950006 124957915

NVI:	100120428 100123291

CSOL:

105363150 105365337

TPRE:

106652605 106654077

LHT:	122510263 122510409

LBD:	127279195 127286470

MDL:	103569010 103569012

CGLO:

123260311 123260952

FAS:	105263496 105263500

DAM:	107043533 107043540

AGIF:

122848840 122855638 122855643

CINS:

118069390 118069434

VCAN:

122415813 122416359

CCIN:

107268310 107268325

DSM:	124413694 124413695

NPT:	124221657 124222441

NFB:	124184661 124185035

NLO:	107223052 107223056

NVG:	124307613 124308134

AROA:

105693368 105693369

TCA:	657497 660457

DPA:	109540727 109543180 109543848

SOY:	115879452 115881960

AGRG:

126736321 126741103

ATD:	109598522 109602069

CSET:

123316101 123319446

AGB:	108907714 108916397

LDC:	111512172 111512410

NVL:	108563723 108565471

APLN:

108734720 108735661 108744059 112903973

PPYR:

116163040 116166612

OTU:	111416187 111416437

BMOR:

101736988 101737814 101744951

BMAN:

114240323 114252968 114253125

MSEX:

115445952 115450888 115452497 119191745

DPL:	KGM_208044 KGM_215409

BANY:

112046823 112055321

MJU:	123874227 123874413 123874526

NIQ:	126773142 126773329 126773508

VCD:	124534624 124534653 124534939

MCIX:

123659080 123659215

PMAC:

106711381 106716352 106716353

PPOT:

106104716 106104717 106105039

PXU:	106119527 106119528 106119552

PRAP:

111003577 111004450 111004459

PBX:	123706840 123706919 123707837

PNAP:

125050319 125050553 125050554

ZCE:

119839682

CCRC:

123698395 123698630 123698632

LSIN:

126967526 126975492 126980138

AAGE:

121734095 121734348

HAW:	110370362 110370403 110376910

HZE:	124636842 124637018 124637135

TNL:	113503402 113503405 113503510

SLIU:

111354977 111355133

OFU:	114357148 114363384 114363605

PXY:	105385618 105387563 105388618 105391615

PGW:	126370654 126371032 126380260

CFEL:

113364179 113377263

CCRN:

123298560 123298561

API:	100160347 100166253 100166270 100168296

DNX:	107164080 107164088 107167019 107167253

AGS:	114120225 114128135 114128137

RMD:	113551386 113551387 113551671

ACOO:

126846098 126847240 126847241

DVT:	126893695 126893896 126896760

BTAB:

109039938 109043107

DCI:	103509644 103517981

CLEC:

106665545 106669239 106670273

HHAL:

106678857 106682716 106691451

NLU:	111060572 111060859 111062054 120355687

HVI:	124361290 124365914 124366056 124366940

MQU:	128991708 129002180 129002230 129003165 129003220 129003825

PHU:	Phum_PHUM399390 Phum_PHUM399960 Phum_PHUM417670

FOC:	113203837 113213284

TPAL:

117645351 117649873

ZNE:	110838066 110838068 110838074

CSEC:

111869203 111870153 111870154

SGRE:

126282040 126282164 126282231 126282233

BROR:

134527159 134533464 134536851

IEL:	124166359 124166885 124166911 124167073

FCD:	110849698 110851933 110854987 110863217 110863220

DPX:	DAPPUDRAFT_203293 DAPPUDRAFT_252082 DAPPUDRAFT_307471 DAPPUDRAFT_319555 DAPPUDRAFT_319556 DAPPUDRAFT_319627 DAPPUDRAFT_319643 DAPPUDRAFT_324595 DAPPUDRAFT_324597 DAPPUDRAFT_324602 DAPPUDRAFT_324603 DAPPUDRAFT_324617

DMK:	116918163 116918420 116918422 116931094 116931095 116931097 116931098 116931099

DPZ:	124313417 124313427 124313437 124313443 124313461 124326054 124329112 124342563 124342565 124342571 124342577

PVM:	113808742 113830543 113830547

PJA:	122246963 122250575

PCHN:

125028320 125047515

PMOO:

119573436 119596306 119596307

HAME:

121868571

PCLA:

123745438 123763023 123763024 123763025

CQD:	128685247 128695098

PTRU:

123499301

ESN:

127009008

MNZ:	135195507 135195508 135195539 135195635 135217234

HAZT:

108665757 108666310 108666312 108669844

EAF:	111695992 111696002 111696004 111699103 111715460 111715461

LSM:	121121914 121130077

TCF:	131878766 131878850 131879002 131879003 131884766 131884988

PPOI:

119099861

ISC:	115310235 8023778

DSV:	119434824 119442632

RSAN:

119385929 119387367 119387434

RMP:	119188309 119188311

VDE:

111250980

VJA:

111273611

TUT:	107361207 107363876 107368145

DPTE:

113789365 113790177 113793769

DFR:	124490443 124490446 124495241 124498112

CSCU:

111619910 111619911 111628710

PTEP:

107439072 107440022 107451369

ABRU:

129957135 129968521 129981015

UDV:	129224714 129224756

SDM:	118183472 118188530 118193367

LPOL:

106460688 106465993 106471363

PMEO:

129588680 129597902 129602579

CEL:	CELE_B0303.11 CELE_Y37A1C.1(nkcc-1)

CBR:	CBG_15341 CBG_18756(Cbr-nkcc-1)

CRQ:	GCK72_008593

NAI:	NECAME_06960 NECAME_07193 NECAME_07194

BMY:	BM_BM12714(Bma-nkcc-1)

LOA:	LOAG_17781

TSP:	Tsp_00989 Tsp_01377 Tsp_02257 Tsp_02836 Tsp_03496

HRO:	HELRODRAFT_116093 HELRODRAFT_157349 HELRODRAFT_74876

LGI:	LOTGIDRAFT_166954 LOTGIDRAFT_177989

PVUL:

126817911 126818900

PCAN:

112554083 112554114 112554583 112554596

BGT:

106050963

GAE:

121386365

HRF:	124118475 124143744

HRJ:	124291054 124291118

CRG:	105322963 105335120

CVN:	111129174 111130898

CANU:

128175047 128176515

OED:	125650490 125651891

MYI:	110453077 110462393

PMAX:

117334508 117335194

MCAF:

127734238 127736031

MMER:

123565369 123566450

RPHI:

132729786 132729787 132729790 132746873

DPOL:

127878151 127878555 127878556

OBI:	106871398 106876733

OSN:	115209475 115216820

LAK:

106167063

NVE:	5513168 5521750

EPA:	110245498 110254759

ATEN:

116288638

ADF:	107328507 107350187 107351920 107358050

AMIL:

114963380 114963382 114963419 114963422 114970796

PDAM:

113666638 113670163

SPIS:

111323570 111336828

DGT:

114520858

XEN:	124439859 124439860

HMG:	100198028 100206298

HSY:	130621429 130622517

TAD:	TRIADDRAFT_22993 TRIADDRAFT_54806

AQU:	100640144 100642121

TVA:	TVAG_2v0518940 TVAG_2v0564660 TVAG_2v0595270 TVAG_2v0666570 TVAG_2v0672990 TVAG_2v0856920

PIN:

Ping_1733

MGEO:

CFI10_08050

DMS:	E8L03_18625

DAT:	HRM2_10560

DTO:	TOL2_C25650

SFU:

Sfum_3620

HOH:

Hoch_6531

BSED:

DN745_17375

PCAY:

FRD00_03110 FRD00_07170

CACE:

CACET_c14780

AWO:	Awo_c18360

EAC:	EAL2_808p06150

DSL:	Dacsa_1651

AMR:

AM1_1273

ACAM:

HRE53_04825

HHG:	XM38_020120

PSEU:

Pse7367_1577

CAN:	Cyan10605_2264

CSN:	Cyast_2814

SYP:	SYNPCC7002_A1963 SYNPCC7002_G0123

SYV:	AWQ23_09855 AWQ23_15205

SYL:	AWQ21_08760

LEP:	Lepto7376_3280

HAO:	PCC7418_3310

ENN:	FRE64_07475

CYU:	UCYN_06530

CYT:

cce_1090

CWA:	CwatDRAFT_4898

CYC:	PCC7424_0857

ARP:	NIES39_K02870

OXY:	HCG48_21590

LFS:	HFV01_03175

OAC:	Oscil6304_4438

MPRO:

BJP34_01015

MIC:	Mic7113_0014

RIV:	Riv7116_2757

CEO:

ETSB_0631

CER:	RGRSB_0595

CEEC:

P3F56_03080

WCH:

wcw_0495

SNG:	SNE_A06490

VBS:	EGM51_11590

MFF:	MFFC18_07210

PLON:

Pla110_34030

CMR:	Cycma_0867

CAMU:

CA2015_0759

FBC:	FB2170_12081

SYI:	SB49_08490

AALG:

AREALGSMS7_03622

AUE:	C5O00_12850

MLT:

VC82_728

FBE:	FF125_10995

CHYD:

H4K34_12035

SRU:

SRU_2259

SRM:	SRM_02486(potE)

MAC:

MA_4506

METM:

MSMTP_0210

MSJ:	MSSAC_4298

MSZ:	MSSIH_3799

MSW:	MSSIT_3876

MZH:	Mzhil_0987

MPY:

Mpsy_0084

MZI:	HWN40_04735

» show all

Reference

PMID:7629105

Authors

Payne JA, Xu JC, Haas M, Lytle CY, Ward D, Forbush B 3rd

Title

Primary structure, functional expression, and chromosomal localization of the bumetanide-sensitive Na-K-Cl cotransporter in human colon.

Journal

J Biol Chem 270:17977-85 (1995)
DOI:10.1074/jbc.270.30.17977

Sequence

[hsa:6558]

Reference

PMID:12739168

Authors

Hebert SC, Mount DB, Gamba G

Title

Molecular physiology of cation-coupled Cl- cotransport: the SLC12 family.

Journal

Pflugers Arch 447:580-93 (2004)
DOI:10.1007/s00424-003-1066-3

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