KEGG   ORTHOLOGY: K11422Help
Entry
K11422                      KO                                     
Name
SETD1, SET1
Definition
histone-lysine N-methyltransferase SETD1 [EC:2.1.1.43]
Pathway
Lysine degradation
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Amino acid metabolism
   00310 Lysine degradation
    K11422  SETD1, SET1; histone-lysine N-methyltransferase SETD1
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.43  histone-lysine N-methyltransferase
     K11422  SETD1, SET1; histone-lysine N-methyltransferase SETD1
Chromosome [BR:ko03036]
 Eukaryotic Type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     K11422  SETD1, SET1; histone-lysine N-methyltransferase SETD1
   HMT complexes
    COMPASS/SET1 complex
     K11422  SETD1, SET1; histone-lysine N-methyltransferase SETD1
    COMPASS/SET1 complex (yeast)
     K11422  SETD1, SET1; histone-lysine N-methyltransferase SETD1
BRITE hierarchy
Other DBs
Genes
HSA: 
23067(SETD1B) 9739(SETD1A)
PTR: 
468101(SETD1A) 473295
PPS: 
100972983(SETD1A)
GGO: 
PON: 
100432076(SETD1A)
MCC: 
MMU: 
208043(Setd1b) 233904(Setd1a)
RNO: 
CFA: 
486257(SETD1B) 489916(SETD1A)
AML: 
FCA: 
101091070(SETD1A) 101096419
BTA: 
514102(SETD1B) 782887(SETD1A)
SSC: 
100511747(SETD1A)
ECB: 
100063523(SETD1A)
MDO: 
100013387(SETD1A) 100618514
SHR: 
100928096 100929291(SETD1A)
OAA: 
100074411 100079266
GGA: 
416851(SETD1B)
TGU: 
100225647(SETD1B)
XLA: 
447454(setd1b)
XTR: 
100487270 780106(setd1b)
DRE: 
556535(setd1a) 567970(setd1ba) 571274(setd1bb)
TRU: 
101071878
OLA: 
101162384 101168786
BFO: 
BRAFLDRAFT_125552
CIN: 
100180709
SPU: 
100893818 586687
DME: 
Dmel_CG40351(Set1)
DPO: 
Dpse_GA26260
DAN: 
Dana_GF23123
DER: 
Dere_GG11901
DPE: 
Dper_GL12290
DSE: 
Dsec_GM18767
DSI: 
Dsim_GD11928
DWI: 
Dwil_GK12911
DYA: 
Dyak_GE25383
DGR: 
Dgri_GH22347
DMO: 
Dmoj_GI23985
DVI: 
Dvir_GJ23622
AGA: 
AgaP_AGAP002246
AAG: 
AaeL_AAEL010807
CQU: 
CpipJ_CPIJ013516
AME: 
411985
NVI: 
100121025(Setd1a)
TCA: 
657811
API: 
100159159 100573227
PHU: 
Phum_PHUM240750
ISC: 
IscW_ISCW009292 IscW_ISCW009293
CEL: 
CELE_C26E6.9(set-2)
BMY: 
Bm1_45235
TSP: 
Tsp_09977
SMM: 
Smp_140390.2
NVE: 
NEMVE_v1g94595
HMG: 
100198749
TAD: 
TRIADDRAFT_32357
AQU: 
100636150
SMO: 
SELMODRAFT_438147
VCN: 
VOLCADRAFT_65362(VSET1)
CME: 
CMG025C
SCE: 
YHR119W(SET1)
AGO: 
AGOS_ABR136W
ERC: 
Ecym_8199
KLA: 
KLLA0F24134g
LTH: 
KLTH0B05280g
PPA: 
PAS_chr2-2_0494
VPO: 
Kpol_1048p18
ZRO: 
ZYRO0G06446g
CGR: 
CAGL0L12980g
NCS: 
NCAS_0B07030(NCAS0B07030)
NDI: 
NDAI_0B04360(NDAI0B04360)
TPF: 
TPHA_0I01480(TPHA0I01480)
TBL: 
TBLA_0C05500(TBLA0C05500)
TDL: 
TDEL_0B05100(TDEL0B05100)
KAF: 
KAFR_0F00700(KAFR0F00700)
DHA: 
DEHA2F20834g
PIC: 
PICST_32740(SET1)
PGU: 
PGUG_00321
LEL: 
LELG_01369
CAL: 
CaO19.13430(SET1) CaO19.6009(SET1)
CTP: 
CTRG_04399
CDU: 
CD36_00910
COT: 
CORT_0B11090
YLI: 
YALI0B14883g
CLU: 
CLUG_03935
NCR: 
NCU01206
SMP: 
SMAC_07534
PAN: 
PODANSg8424
TTT: 
THITE_129744
MTM: 
MYCTH_79077
FGR: 
FG07445.1
NHE: 
NECHADRAFT_49470(SDG2101)
VAL: 
VDBG_04198
SSL: 
SS1G_03070
BFU: 
BC1G_06306 BC1G_06307
ANI: 
AN5795.2
NFI: 
NFIA_051950
AFM: 
AFUA_6G06335
AOR: 
AOR_1_4154(AO090003000002)
ANG: 
ANI_1_1490164(An18g06840)
AFV: 
AFLA_037970
ACT: 
ACLA_088100
PCS: 
Pc14g00900
CIM: 
CIMG_07257
CPW: 
CPC735_000650
PBL: 
PAAG_00848
URE: 
UREG_07821
ABE: 
ARB_00972
TVE: 
TRV_00712
AJE: 
HCAG_04084
PNO: 
SNOG_03803
PTE: 
PTT_01686
ZTR: 
MYCGRDRAFT_10108(SDG2403)
TML: 
GSTUM_00009579001
SPO: 
SPCC306.04c(set1)
CNE: 
CND03610
CNB: 
CNBD2720
CGI: 
CGB_D6310C
PPL: 
POSPLDRAFT_89758
LBC: 
LACBIDRAFT_233519(SDG16201)
CCI: 
CC1G_15535
SCM: 
SCHCODRAFT_77129
UMA: 
UM02677.1
MGL: 
MGL_4221
PGR: 
PGTG_01930 PGTG_20780
MBR: 
MONBRDRAFT_10803
NGR: 
NAEGRDRAFT_4440
DDI: 
DDB_G0289257(set1)
DPP: 
DICPUDRAFT_150684
TVA: 
TVAG_440830
PTI: 
PHATRDRAFT_15937
TPS: 
THAPSDRAFT_35182
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Wysocka J, Myers MP, Laherty CD, Eisenman RN, Herr W
  Title
Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1.
  Journal
Genes Dev 17:896-911 (2003)
Reference
  Authors
Boa S, Coert C, Patterton HG
  Title
Saccharomyces cerevisiae Set1p is a methyltransferase specific for lysine 4 of histone H3 and is required for efficient gene expression.
  Journal
Yeast 20:827-35 (2003)
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