KEGG   ORTHOLOGY: K11832Help
Entry
K11832                      KO                                     
Name
USP1
Definition
ubiquitin carboxyl-terminal hydrolase 1 [EC:3.1.2.15]
Pathway
Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Replication and repair
   03460 Fanconi anemia pathway
    K11832  USP1; ubiquitin carboxyl-terminal hydrolase 1
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.2  Thioester hydrolases
    3.1.2.15  ubiquitin thiolesterase
     K11832  USP1; ubiquitin carboxyl-terminal hydrolase 1
Peptidases [BR:ko01002]
 Cysteine Peptidases
  Family C19: ubiquitin-specific protease family
   K11832  USP1; ubiquitin carboxyl-terminal hydrolase 1
Ubiquitin system [BR:ko04121]
 Deubiquitinating enzyme (DUB)
  Ubiquitin-specific proteases (UBPs)
   UBP/USP
    K11832  USP1; ubiquitin carboxyl-terminal hydrolase 1
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  DSBR (double strand breaks repair)
   FA (Fanconi anemia) pathway
    Other FA pathway factors
     K11832  USP1; ubiquitin carboxyl-terminal hydrolase 1
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
7398(USP1)
PTR: 
456901(USP1)
PPS: 
100982030(USP1)
GGO: 
101124390(USP1)
PON: 
100443075(USP1)
MCC: 
695157(USP1)
MMU: 
230484(Usp1)
RNO: 
313387(Usp1)
CFA: 
479549(USP1)
AML: 
100473360(USP1)
FCA: 
101080903(USP1)
BTA: 
516328(USP1)
SSC: 
100523071(USP1)
ECB: 
100070397(USP1)
MDO: 
100031700(USP1)
SHR: 
100919331(USP1)
GGA: 
424685(USP1)
MGP: 
100550349
TGU: 
100218324(USP1)
ACS: 
100560711(usp1)
XLA: 
447465(usp1)
XTR: 
780036(usp1)
DRE: 
322007(usp1)
TRU: 
101070932
OLA: 
101167111
BFO: 
BRAFLDRAFT_118958
SPU: 
576951
DME: 
Dmel_CG15817
DPO: 
Dpse_GA13968
DAN: 
Dana_GF16609
DER: 
Dere_GG11658
DPE: 
Dper_GL13883
DSE: 
Dsec_GM12779
DSI: 
Dsim_GD21429
DWI: 
Dwil_GK22674
DYA: 
Dyak_GE23847
DGR: 
Dgri_GH14306
DMO: 
Dmoj_GI10403
DVI: 
Dvir_GJ14517
AGA: 
AgaP_AGAP000884
AAG: 
AaeL_AAEL011287
CQU: 
CpipJ_CPIJ014662
AME: 
409389
NVI: 
100216456
TCA: 
657237
API: 
100162534
PHU: 
Phum_PHUM411860
NVE: 
NEMVE_v1g124883
MBR: 
MONBRDRAFT_27754
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Reyes-Turcu FE, Ventii KH, Wilkinson KD
  Title
Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes.
  Journal
Annu Rev Biochem 78:363-97 (2009)
Reference
  Authors
Nijman SM, Huang TT, Dirac AM, Brummelkamp TR, Kerkhoven RM, D'Andrea AD, Bernards R
  Title
The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway.
  Journal
Mol Cell 17:331-9 (2005)
Reference
  Authors
Murai J, Yang K, Dejsuphong D, Hirota K, Takeda S, D'Andrea AD
  Title
The USP1/UAF1 Complex Promotes Double-Strand Break Repair through Homologous Recombination.
  Journal
Mol Cell Biol 31:2462-9 (2011)
DBGET integrated database retrieval system