KEGG   ORTHOLOGY: K11832Help
Entry
K11832                      KO                                     

Name
USP1
Definition
ubiquitin carboxyl-terminal hydrolase 1 [EC:3.1.2.15]
Pathway
Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Replication and repair
   03460 Fanconi anemia pathway
    K11832  USP1; ubiquitin carboxyl-terminal hydrolase 1
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.2  Thioester hydrolases
    3.1.2.15  ubiquitin thiolesterase
     K11832  USP1; ubiquitin carboxyl-terminal hydrolase 1
Peptidases [BR:ko01002]
 Cysteine Peptidases
  Family C19: ubiquitin-specific protease family
   K11832  USP1; ubiquitin carboxyl-terminal hydrolase 1
Ubiquitin system [BR:ko04121]
 Deubiquitinating enzyme (DUB)
  Ubiquitin-specific proteases (UBPs)
   UBP/USP
    K11832  USP1; ubiquitin carboxyl-terminal hydrolase 1
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  DSBR (double strand breaks repair)
   FA (Fanconi anemia) pathway
    Other FA pathway factors
     K11832  USP1; ubiquitin carboxyl-terminal hydrolase 1
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
7398(USP1)
PTR: 
456901(USP1)
PPS: 
100982030(USP1)
GGO: 
101124390(USP1)
PON: 
100443075(USP1)
NLE: 
100593568(USP1)
MCC: 
695157(USP1)
MCF: 
102140426(USP1)
CJC: 
100411303(USP1)
MMU: 
230484(Usp1)
RNO: 
313387(Usp1)
CGE: 
100754655(Usp1)
HGL: 
101716794(Usp1)
TUP: 
102496372(USP1)
CFA: 
479549(USP1)
AML: 
100473360(USP1)
UMR: 
103663070(USP1)
FCA: 
101080903(USP1)
PTG: 
102965527(USP1)
BTA: 
516328(USP1)
BOM: 
102275237(USP1)
PHD: 
102329628(USP1)
CHX: 
102187448(USP1)
OAS: 
101107236(USP1)
SSC: 
100523071(USP1)
CFR: 
102522295(USP1)
BACU: 
103008560(USP1)
LVE: 
103085454(USP1)
ECB: 
100070397(USP1)
MYB: 
102252055(USP1)
MYD: 
PALE: 
102898461(USP1)
MDO: 
100031700(USP1)
SHR: 
100919331(USP1)
GGA: 
424685(USP1)
MGP: 
APLA: 
101791738(USP1)
TGU: 
100218324(USP1)
FAB: 
101819959(USP1)
PHI: 
102114174(USP1)
FPG: 
101920556(USP1)
FCH: 
102058157(USP1)
CLV: 
102096717(USP1)
ASN: 
102384046(USP1)
AMJ: 
102558353(USP1)
PSS: 
102446936(USP1)
CMY: 
102935301(USP1)
ACS: 
100560711(usp1)
PBI: 
103053739(USP1)
XLA: 
447465(usp1)
XTR: 
780036(usp1)
DRE: 
322007(usp1)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102364423(USP1)
CMK: 
103188830(usp1)
BFO: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
409389(GB13990)
NVI: 
TCA: 
BMOR: 
API: 
PHU: 
LGI: 
NVE: 
CCP: 
MBR: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Nijman SM, Huang TT, Dirac AM, Brummelkamp TR, Kerkhoven RM, D'Andrea AD, Bernards R
  Title
The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway.
  Journal
Mol Cell 17:331-9 (2005)
  Sequence
[hsa:7398]
Reference
  Authors
Murai J, Yang K, Dejsuphong D, Hirota K, Takeda S, D'Andrea AD
  Title
The USP1/UAF1 Complex Promotes Double-Strand Break Repair through Homologous Recombination.
  Journal
Mol Cell Biol 31:2462-9 (2011)
  Sequence
[gga:424685]

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