KEGG ORTHOLOGY: K11989

ORTHOLOGY: K11989

Entry

K11989                      KO

Symbol

IHH

Name

indian hedgehog

Pathway

map04340

Hedgehog signaling pathway

map05205

Proteoglycans in cancer

Disease

H00482

Brachydactyly

H00675

Acrocapitofemoral dysplasia

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    K11989  IHH; indian hedgehog
09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K11989  IHH; indian hedgehog
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K11989  IHH; indian hedgehog
Peptidases and inhibitors [BR:ko01002]
Cysteine peptidases
  Family C46: hedgehog family
   K11989  IHH; indian hedgehog

Other DBs

GO:

0005113

Genes

HSA:

3549(IHH)

PTR:	470652(IHH)

PPS:	100989487(IHH)

GGO:	101148138(IHH)

PON:	100443093(IHH)

NLE:	100580536(IHH)

HMH:	116809459(IHH)

MCC:	704046(IHH)

MCF:	102136990(IHH)

MTHB:

126933004

MNI:	105481245(IHH)

CSAB:

103217894(IHH)

CATY:

105587043(IHH)

PANU:

101008673(IHH)

TGE:	112636384(IHH)

MLEU:

105528101(IHH)

RRO:	104660042(IHH)

RBB:	108518479(IHH)

TFN:	117094504(IHH)

PTEH:

111546124(IHH)

CANG:

105504710(IHH)

CJC:	100396668(IHH)

SBQ:	101027525(IHH)

CIMI:

108309083(IHH)

CSYR:

103261274(IHH)

MMUR:

105857715(IHH)

LCAT:

123643989(IHH)

PCOQ:

105808761(IHH)

OGA:	100946168(IHH)

MMU:	16147(Ihh)

MCAL:

110299104(Ihh)

MPAH:

110322250(Ihh)

RNO:	84399(Ihh)

MCOC:

116089232(Ihh)

ANU:	117705770(Ihh)

MUN:	110566358(Ihh)

CGE:	100774896(Ihh)

MAUA:

101831302(Ihh)

PROB:

127226452(Ihh)

PLEU:

114709305(Ihh)

MORG:

121447083(Ihh)

MFOT:

126492948

AAMP:

119821468(Ihh)

NGI:	103727737(Ihh)

HGL:	101697444(Ihh)

CPOC:

100723067(Ihh)

CCAN:

109691081(Ihh)

DORD:

105999256(Ihh)

DSP:	122107408(Ihh)

PLOP:

125350292(Ihh)

NCAR:

124978887

MMMA:

107138710(Ihh)

OCU:

100008942

OPI:	101517202(IHH)

TUP:	102481154(IHH)

GVR:	103583002 103598681(IHH)

CFA:	488533(IHH)

CLUD:

112656444(IHH)

VVP:	112922445(IHH)

VLG:	121480791(IHH)

NPO:	129522895(IHH)

AML:	100466890(IHH)

UMR:	103662884(IHH)

UAH:	113250443(IHH)

UAR:	123779461(IHH)

ELK:

111145286

LLV:

125095297

MPUF:

101679016(IHH)

MNP:	132013562(IHH)

MLK:	131827436(IHH)

NVS:	122902321(IHH)

ORO:	101376336(IHH)

EJU:	114200198(IHH)

ZCA:	113919241(IHH)

MLX:	118011746(IHH)

NSU:	110592195(IHH)

LWW:	102726022(IHH)

FCA:	101100146(IHH)

PYU:	121031089(IHH)

PCOO:

112867096(IHH)

PBG:	122481788(IHH)

PVIV:

125172847(IHH)

LRUF:

124514123

PTG:	102956863(IHH)

PPAD:

109265043(IHH)

PUC:

125911163

AJU:

106970069

HHV:	120232439(IHH)

BTA:	522714(IHH)

BOM:	102277371(IHH)

BIU:	109570829(IHH)

BBUB:

102405399(IHH)

BBIS:

105003862(IHH)

CHX:	102179616(IHH)

OAS:	101113658(IHH)

BTAX:

128043611(IHH)

ODA:	120854356(IHH)

CCAD:

122426564(IHH)

MBEZ:

129538121(IHH)

SSC:	397174(IHH)

CFR:	102519022(IHH)

CBAI:

105064029(IHH)

CDK:	105096134(IHH)

VPC:	102534509(IHH)

BACU:

103001238(IHH)

BMUS:

118898102(IHH)

LVE:	103077849(IHH)

OOR:	101286749(IHH)

DLE:	111172093(IHH)

PCAD:

102991538(IHH)

PSIU:

116756633(IHH)

NASI:

112411866(IHH)

ECB:	100033984(IHH)

EPZ:	103557450(IHH)

EAI:	106840565(IHH)

MYB:	102257284(IHH)

MYD:	102759193(IHH)

MMYO:

118661034(IHH)

MLF:	102426224(IHH)

PKL:	118709595(IHH)

EFUS:

103289304(IHH)

MNA:	107524852(IHH)

DRO:	112307927(IHH)

SHON:

118975389(IHH)

AJM:	119056905(IHH)

PDIC:

114494490(IHH)

PHAS:

123829791(IHH)

MMF:	118625692(IHH)

PPAM:

129080628(IHH)

HAI:	109380538(IHH)

RFQ:	117026349(IHH)

PALE:

102883197(IHH)

PGIG:

120587672(IHH)

PVP:	105291048(IHH)

RAY:	107516788(IHH)

MJV:	108392422(IHH)

TOD:	119256222(IHH)

SARA:

101552402(IHH)

SETR:

126000869(IHH)

LAV:	100673348(IHH)

TMU:

101348175

ETF:	101662543(IHH)

DNM:	101436771(IHH)

MDO:	100010841(IHH)

GAS:	123241935(IHH)

SHR:	100917246(IHH)

AFZ:

127553089

PCW:	110219461(IHH)

OAA:	114811996(IHH)

GGA:	395801(IHH)

PCOC:

116227304(IHH)

CJO:	107317031(IHH)

TPAI:

128077093(IHH)

LMUT:

125696714(IHH)

NMEL:

110399848(IHH)

APLA:

119717489(IHH)

ACYG:

106039309(IHH)

CATA:

118252631(IHH)

AFUL:

116490892(IHH)

TGU:	100227556(IHH)

LSR:	110468349(IHH)

SCAN:

103814668(IHH)

PMOA:

120498542(IHH)

OTC:	121335732(IHH)

PRUF:

121356793(IHH)

GFR:	102037302(IHH)

FAB:	101816193(IHH)

OMA:	130255697(IHH)

PHI:	102102115(IHH)

PMAJ:

107207183(IHH)

CCAE:

111943238 111945599

CCW:	104694188(IHH)

CBRC:

103611289(IHH)

ETL:	114055175(IHH)

ZAB:	102066244(IHH)

SVG:	106860307(IHH)

MMEA:

130574384(IHH)

HRT:	120755144(IHH)

FPG:	101921899(IHH)

FCH:	102055096(IHH)

CLV:	102086639(IHH)

NNI:	104010064(IHH)

ACUN:

113482128(IHH)

TALA:

104369183(IHH)

PADL:

103917683(IHH)

AFOR:

103895434(IHH)

ACHC:

115343372(IHH)

HLE:	104832106(IHH)

AGEN:

126039565

GCL:

127018636

MUI:

104543832

LDI:	104347840(IHH)

NNT:	104403287(IHH)

SHAB:

115608275(IHH)

DPUB:

104309800(IHH)

CPEA:

104387494(IHH)

CVF:	104285582(IHH)

RTD:	128912715(IHH)

CUCA:

104056584(IHH)

BRHI:

104499905(IHH)

AROW:

112971984(IHH)

NPD:	112946349(IHH)

DNE:	112997430(IHH)

ASN:

102380714

AMJ:

106737314

CMY:	114019618(IHH)

CCAY:

125644592(IHH)

DCC:	119863489(IHH)

CPIC:

101931387

CABI:

116831548(IHH)

MRV:	120374267(IHH)

ACS:	100567635(ihh)

ASAO:

132773801(IHH)

PVT:	110078171(IHH)

SUND:

121918916(IHH)

PBI:	103055572(IHH)

PMUR:

107291499(IHH)

CTIG:

120310412(IHH)

TSR:	106546241(IHH)

PGUT:

117675259(IHH)

PTEX:

113441204(IHH)

NSS:	113410814(IHH)

VKO:	123027437(IHH)

PMUA:

114603126(IHH)

PRAF:

128420337(IHH)

ZVI:	118090919(IHH)

HCG:	128341006(IHH)

GJA:	107113952(IHH)

STOW:

125425824(IHH)

EMC:	129325216(IHH)

XLA:	108701295(ihh.L) 378540(ihh.S)

XTR:	100145111(ihh)

NPR:	108785789(IHH)

RTEM:

120944212(IHH)

BBUF:

121008218(IHH)

BGAR:

122945754(IHH)

MUO:	115474649(IHH)

GSH:	117360650(IHH)

DRE:	30299(ihhb) 619520(ihha)

SRX:	107713117 107716791 107721594

SANH:

107660113 107668405 107688738

SGH:	107551082 107551900 107602904

CCAR:

109048560 109056610 109108992

CAUA:

113050928 113053671 113091441 113108891

CGIB:

127959661 127965595 128015348 128019416

PTET:

122347116(ihhb) 122352074(ihha)

LROH:

127166398(ihhb) 127171328(ihha)

OMC:	131541827(ihhb) 131547499(ihha)

PPRM:

120487213(ihha) 120491584(ihhb)

RKG:	130078154(ihha) 130101270(ihhb)

MAMB:

125270021(ihha) 125274160(ihhb)

CIDE:

127514630 127518957

MASI:

127446682 127447461 127448465 127448833

TROS:

130555748(ihha) 130556510(ihhb)

TDW:	130424429(ihhb) 130427182(ihha)

MANU:

129451091(ihhb) 129452560(ihha)

IPU:	108266733(ihha)

IFU:	128608995(ihha)

PHYP:

113546725

SMEO:

124383258(ihha)

TFD:	113654558(ihha)

TVC:	132850313(ihha)

AMEX:

103035832 103040705

CMAO:

118807025(ihha) 118808079(ihhb)

EEE:	113579961 113584292

CHAR:

105891314 105903006

TRU:	101061568 101066095

TFS:	130522042 130533666

TNG:	GSTEN00030492G001

LCO:	104934612(ihh)

NCC:	104949666 104963304

TBEN:

117485910 117486799

CGOB:

115026224

PGEO:

117444846 117466223

GACU:

117538337(ihha)

EMAC:

134860943 134867787

ELY:

117250012

EFO:	125884842 125900040

PLEP:

121948981(ihha) 121965117

SLUC:

116044539 116049927

ECRA:

117939205 117952777(ihha)

ESP:	116674185(ihh) 116697697

PFLV:

114551012 114563661

GAT:	120819658 120833855

PPUG:

AFB:

CLUM:

PSWI:

MSAM:

SCHU:

CUD:	121506110 121522262

ALAT:

119015258 119026334

MZE:	101469964 101472658

ONL:	100703074 100706920

OAU:	116312914 116316902

OLA:	100125500 101170159

OML:	112154992 112156801

CSAI:

133425420 133446026

XMA:	102224207 102229925

XCO:

114148134

XHE:	116716067 116723675

PRET:

103456683 103461635

PFOR:

103154122(ihh) 103156544 103156546

PLAI:

106949517(ihh) 106961420

PMEI:

106904312 106905940 106919591(ihh)

GAF:	122826957 122839690

PPRL:

129361460(ihha)

CVG:	107096823(ihh) 107103858

CTUL:

119788719 119794672

GMU:	124861945 124871147

NFU:	107384638(ihh) 107390160

KMR:	108240386(ihha)

ALIM:

106527019(ihh) 106527444

NWH:	119419081 119428956

AOCE:

111582838 111588276

MCEP:

125000666 125017337

CSEM:

103389238(ihh) 103392080

POV:	109631096 109640223

SSEN:

122765005 122786800

HHIP:

117754699 117777221

HSP:	118103173 118119625

SMAU:

118282761 118314018

LCF:	108873130 108880474

SDU:	111218276 111234765(ihh)

SLAL:

111671496 111672455

XGL:	120798159 120801110

HCQ:	109523373 109528665(ihh)

SSCV:

125973674 125988477

SBIA:

133507166 133512183

PEE:	133405864 133410986

PTAO:

133480759 133486424

BPEC:

110159958 110166001

MALB:

109955659(ihh) 109964396

BSPL:

114847652(ihha)

SJO:	128354621(ihhb) 128367565(ihha)

SASA:

106574860 106575859 106582516(ihh) 106586914

STRU:

115155444 115161420 115180870(ihh) 115182103

OTW:	112224977(ihha) 112237908 112238884

OMY:	110495551 110495566 110501953 110509417

OGO:	124019578 124031360 124043035

ONE:	115120387 115131345

OKI:	109875783 109885041 109885758

OKE:	118366451 118380473 118386451

SALP:

112073391 112077615

SNH:	120035282 120036505 120051514

CCLU:

121536447 121555122 121560756

ELS:	105023172 105027293

SFM:

108942415

PKI:

111852207

AANG:

118222373(ihha)

LOC:	102695677(ihh)

PSPA:

121323353(ihha)

ARUT:

117414002(ihha)

PSEX:

120531262(ihha)

LCM:	102361963(IHH)

CMK:

RTP:

CPLA:

HOC:

LERI:

LRJ:	133340047 133361952 133362328

BFO:

118413679

CIN:	445637(hh2)

AJC:

SKO:

NPT:

NFB:

NLO:

NVG:

SOY:

ACOO:

FOC:

TPAL:

IEL:

FCD:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

ESN:

HAZT:

PPOI:

RSAN:

RMP:

VDE:

VJA:

ABRU:

UDV:

SDM:

LPOL:

BGT:

GAE:	121369497 121373226 121373409 121373588 121373610 121376828 121385425 121385571 121392430

HRF:	124112166 124112190

HRJ:	124259189 124268747

MYI:

110459370

NVE:	5507649 5515501

EPA:	110232141 110251947

ATEN:

116300831

ADF:	107331333 107335503

AMIL:

PDAM:

SPIS:

DGT:

MBR:	MONBRDRAFT_36484

» show all

Reference

PMID:7590746

Authors

Marigo V, Roberts DJ, Lee SM, Tsukurov O, Levi T, Gastier JM, Epstein DJ, Gilbert DJ, Copeland NG, Seidman CE, et al.

Title

Cloning, expression, and chromosomal location of SHH and IHH: two human homologues of the Drosophila segment polarity gene hedgehog.

Journal

Genomics 28:44-51 (1995)
DOI:10.1006/geno.1995.1104

Sequence

[hsa:3549]

Reference

PMID:21537345

Authors

Ma G, Yu J, Xiao Y, Chan D, Gao B, Hu J, He Y, Guo S, Zhou J, Zhang L, Gao L, Zhang W, Kang Y, Cheah KS, Feng G, Guo X, Wang Y, Zhou CZ, He L

Title

Indian hedgehog mutations causing brachydactyly type A1 impair Hedgehog signal transduction at multiple levels.

Journal

Cell Res 21:1343-57 (2011)
DOI:10.1038/cr.2011.76

Sequence

[hsa:3549]

All links

Ontology (3)   
   KEGG BRITE (2)   
   GO (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (2)   
   KEGG DISEASE (2)   
Gene (1193)   
   KEGG GENES (544)   
   KEGG MGENES (77)   
   RefGene (569)   
   OC (3)   
Literature (2)   
   PubMed (2)   
All databases (1204)   

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