KEGG   ORTHOLOGY: K12316Help
Entry
K12316                      KO                                     

Name
GAA
Definition
lysosomal alpha-glucosidase [EC:3.2.1.20]
Pathway
Galactose metabolism
Starch and sucrose metabolism
Lysosome
Disease
H00069  
Glycogen storage diseases (GSD)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Carbohydrate metabolism
   00052 Galactose metabolism
    K12316  GAA; lysosomal alpha-glucosidase
   00500 Starch and sucrose metabolism
    K12316  GAA; lysosomal alpha-glucosidase
 Cellular Processes
  Transport and catabolism
   04142 Lysosome
    K12316  GAA; lysosomal alpha-glucosidase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.20  alpha-glucosidase
     K12316  GAA; lysosomal alpha-glucosidase
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K12316  GAA; lysosomal alpha-glucosidase
BRITE hierarchy
Other DBs
Genes
HSA: 
2548(GAA)
PTR: 
454940(GAA)
PPS: 
GGO: 
PON: 
NLE: 
MCC: 
712054(GAA)
MCF: 
CJC: 
MMU: 
14387(Gaa)
RNO: 
367562(Gaa)
CGE: 
NGI: 
HGL: 
OCU: 
TUP: 
CFA: 
483352(GAA)
AML: 
UMR: 
FCA: 
PTG: 
BTA: 
280798(GAA)
BOM: 
PHD: 
CHX: 
OAS: 
SSC: 
CFR: 
BACU: 
LVE: 
ECB: 
MYB: 
MYD: 
PALE: 
MDO: 
SHR: 
OAA: 
GGA: 
MGP: 
APLA: 
TGU: 
FAB: 
PHI: 
FPG: 
FCH: 
CLV: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
XTR: 
DRE: 
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
CIN: 
SPU: 
AME: 
409365(GB11933)
NVI: 
TCA: 
API: 
PHU: 
ISC: 
HRO: 
LGI: 
SMM: 
NVE: 
HMG: 
AQU: 
DDI: 
DFA: 
PTM: 
PIF: 
GTT: 
NGR: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Maga JA, Zhou J, Kambampati R, Peng S, Wang X, Bohnsack RN, Thomm A, Golata S, Tom P, Dahms NM, Byrne BJ, LeBowitz JH
  Title
Glycosylation-independent lysosomal targeting of acid alpha-glucosidase enhances  muscle glycogen clearance in pompe mice.
  Journal
J Biol Chem 288:1428-38 (2013)
Reference
  Authors
Esmer C, Becerra-Becerra R, Pena-Zepeda C, Bravo-Oro A
  Title
A novel homozygous mutation at the GAA gene in Mexicans with early-onset Pompe disease.
  Journal
Acta Myol 32:95-9 (2013)
  Sequence
[hsa:2548]

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