KEGG   ORTHOLOGY: K12361
Entry
K12361                      KO                                     
Symbol
RASGRP2
Name
RAS guanyl-releasing protein 2
Pathway
map04010  MAPK signaling pathway
map04014  Ras signaling pathway
map04015  Rap1 signaling pathway
map04062  Chemokine signaling pathway
map04611  Platelet activation
map05200  Pathways in cancer
Disease
H01235  Bleeding disorder platelet-type
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K12361  RASGRP2; RAS guanyl-releasing protein 2
   04014 Ras signaling pathway
    K12361  RASGRP2; RAS guanyl-releasing protein 2
   04015 Rap1 signaling pathway
    K12361  RASGRP2; RAS guanyl-releasing protein 2
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    K12361  RASGRP2; RAS guanyl-releasing protein 2
   04062 Chemokine signaling pathway
    K12361  RASGRP2; RAS guanyl-releasing protein 2
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K12361  RASGRP2; RAS guanyl-releasing protein 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified
    K12361  RASGRP2; RAS guanyl-releasing protein 2
Domain-containing proteins not elsewhere classified [BR:ko04990]
 EF-hand domain-containing proteins
  Other EF-hand domain-containing proteins
   K12361  RASGRP2; RAS guanyl-releasing protein 2
Other DBs
GO: 0005088
Genes
HSA: 10235(RASGRP2)
PTR: 451298(RASGRP2)
PPS: 100993077(RASGRP2)
GGO: 101125864(RASGRP2)
PON: 100447844(RASGRP2)
NLE: 100603817(RASGRP2)
HMH: 116468962(RASGRP2)
MCC: 722044(RASGRP2)
MCF: 102139509(RASGRP2)
MTHB: 126935564
MNI: 105469529(RASGRP2)
CSAB: 103233086(RASGRP2)
CATY: 105577479(RASGRP2)
PANU: 100137599(RASGRP2)
TGE: 112606964(RASGRP2)
MLEU: 105549110(RASGRP2)
RRO: 104673274(RASGRP2)
RBB: 108542853(RASGRP2)
TFN: 117081424(RASGRP2)
PTEH: 111522280(RASGRP2)
CANG: 105512200(RASGRP2)
CJC: 100896269(RASGRP2)
SBQ: 101053574(RASGRP2)
CIMI: 108310283(RASGRP2)
CSYR: 103256290(RASGRP2)
MMUR: 105878487(RASGRP2)
LCAT: 123641412(RASGRP2)
PCOQ: 105827379(RASGRP2)
OGA: 100942339(RASGRP2)
MMU: 19395(Rasgrp2)
MCAL: 110285321(Rasgrp2)
MPAH: 110318723(Rasgrp2)
RNO: 361714(Rasgrp2)
MCOC: 116103453(Rasgrp2)
ANU: 117709994(Rasgrp2)
MUN: 110549343(Rasgrp2)
CGE: 100757059(Rasgrp2)
MAUA: 101840143(Rasgrp2)
PROB: 127228740(Rasgrp2)
PLEU: 114680696(Rasgrp2)
MORG: 121454202(Rasgrp2)
MFOT: 126498235
AAMP: 119802087(Rasgrp2)
NGI: 103738782(Rasgrp2)
HGL: 101714183(Rasgrp2)
CPOC: 100722152(Rasgrp2)
CCAN: 109687177(Rasgrp2)
DORD: 105989216(Rasgrp2)
DSP: 122104915(Rasgrp2)
PLOP: 125362619(Rasgrp2)
NCAR: 124958788
MMMA: 107135982(Rasgrp2)
OPI: 101517768(RASGRP2)
TUP: 102468592(RASGRP2)
GVR: 103590620(RASGRP2)
CFA: 612101(RASGRP2)
CLUD: 112659488(RASGRP2)
VVP: 112924301(RASGRP2)
VLG: 121501819(RASGRP2)
NPO: 129503115(RASGRP2)
AML: 105236463(RASGRP2)
UMR: 103679557(RASGRP2)
UAH: 113244161(RASGRP2)
UAR: 123778290(RASGRP2)
ELK: 111149468
LLV: 125078503
MPUF: 101678429(RASGRP2)
MNP: 132019319(RASGRP2)
MLK: 131814933(RASGRP2)
NVS: 122913071(RASGRP2)
ORO: 101369676(RASGRP2)
EJU: 114220482(RASGRP2)
ZCA: 113914097(RASGRP2)
MLX: 118016009(RASGRP2)
NSU: 110575955(RASGRP2)
LWW: 102750966(RASGRP2)
FCA: 101094450(RASGRP2)
PYU: 121023900(RASGRP2)
PBG: 122483972(RASGRP2)
PVIV: 125147101(RASGRP2)
LRUF: 124504875
PTG: 102958860(RASGRP2)
PPAD: 109246682(RASGRP2)
PUC: 125931466
AJU: 106981708
HHV: 120240123(RASGRP2)
BTA: 512056(RASGRP2)
BOM: 102264750(RASGRP2)
BIU: 109554073 109554125
BBUB: 102391415(RASGRP2)
BBIS: 104987195(RASGRP2)
CHX: 102168515(RASGRP2)
OAS: 101104023(RASGRP2)
BTAX: 128068739(RASGRP2)
ODA: 120874643(RASGRP2)
CCAD: 122430799(RASGRP2)
MBEZ: 129548806(RASGRP2)
SSC: 100626093(RASGRP2)
CFR: 102515600(RASGRP2)
CBAI: 105070645(RASGRP2)
CDK: 105101557(RASGRP2)
VPC: 102542043(RASGRP2)
BACU: 103000066(RASGRP2)
BMUS: 118899994(RASGRP2)
LVE: 103078201(RASGRP2)
OOR: 101278371(RASGRP2)
DLE: 111183796(RASGRP2)
PCAD: 102990537
PSIU: 116757885(RASGRP2)
NASI: 112402393(RASGRP2)
ECB: 102150244(RASGRP2)
EPZ: 103565063(RASGRP2)
EAI: 106833617(RASGRP2)
MYB: 102242639(RASGRP2)
MYD: 102766192(RASGRP2)
MMYO: 118665351(RASGRP2)
MLF: 102427498(RASGRP2)
PKL: 118714968(RASGRP2)
EFUS: 103302054(RASGRP2)
MNA: 107542784(RASGRP2)
DRO: 112317389(RASGRP2)
SHON: 118991686(RASGRP2)
AJM: 119050243(RASGRP2)
PDIC: 114500603(RASGRP2)
PHAS: 123829277(RASGRP2)
MMF: 118628048(RASGRP2)
PPAM: 129068603(RASGRP2)
HAI: 109384326(RASGRP2)
RFQ: 117029919(RASGRP2)
PALE: 102896690(RASGRP2)
PGIG: 120600706(RASGRP2)
PVP: 105297993(RASGRP2)
RAY: 107517268(RASGRP2)
MJV: 108396371(RASGRP2)
TOD: 119250013(RASGRP2)
SARA: 101552845(RASGRP2)
SETR: 126019028(RASGRP2)
LAV: 100661291(RASGRP2)
TMU: 101347941
ETF: 101660297(RASGRP2)
DNM: 101431978(RASGRP2)
GAS: 123253095(RASGRP2)
SHR: 100916150(RASGRP2)
AFZ: 127540089
PCW: 110195541(RASGRP2)
OAA: 100090421(RASGRP2)
PHI: 106628736(RASGRP2)
SHAB: 115602966
AROW: 112967180
ASN: 102372838(RASGRP2)
AMJ: 102566493(RASGRP2)
PSS: 102445100(RASGRP2)
CMY: 102937915(RASGRP2)
CCAY: 125640235(RASGRP2)
DCC: 119858970(RASGRP2)
CPIC: 101946976(RASGRP2)
TST: 117880418(RASGRP2)
CABI: 116835374(RASGRP2)
MRV: 120368749(RASGRP2)
ACS: 103282338
ASAO: 132764363(RASGRP2)
PVT: 110083762(RASGRP2)
SUND: 121916085(RASGRP2)
PBI: 103054829
PMUR: 107289925(RASGRP2)
CTIG: 120318482(RASGRP2)
PGUT: 117669710(RASGRP2)
APRI: 131186521(RASGRP2)
PTEX: 113447484(RASGRP2)
NSS: 113424368(RASGRP2)
VKO: 123032547(RASGRP2)
PMUA: 114586605(RASGRP2)
PRAF: 128403787(RASGRP2)
ZVI: 118076297(RASGRP2)
HCG: 128337328(RASGRP2)
GJA: 107121068(RASGRP2)
STOW: 125442732(RASGRP2)
EMC: 129337135(RASGRP2)
XLA: 379250(rasgrp2.S) 447008(rasgrp2.L)
XTR: 101733706(rasgrp2)
NPR: 108800280(RASGRP2)
RTEM: 120916813(RASGRP2)
BBUF: 120980454(RASGRP2)
BGAR: 122920212(RASGRP2)
MUO: 115479883(RASGRP2)
GSH: 117365668(RASGRP2)
DRE: 557063(rasgrp2) 797658
SRX: 107715264 107723918 107742920 107745297
SANH: 107675419 107684742 107691821 107693929
SGH: 107550175 107557050 107560656 107601176
CCAR: 109045914 109064382 109085422
CAUA: 113038485 113051726 113064078 113106392
CGIB: 127942079 127961510 127986591 128016430
PTET: 122326088(rasgrp2) 122348779
LROH: 127152742(rasgrp2) 127168114
OMC: 131529312(rasgrp2) 131544217
PPRM: 120477835 120494593(rasgrp2)
RKG: 130072824 130095300(rasgrp2)
MAMB: 125252910(rasgrp2) 125263983
CIDE: 127503906 127515925
MASI: 127431259 127441630
TROS: 130570195(rasgrp2)
TDW: 130407549(rasgrp2)
MANU: 129423661(rasgrp2)
IPU: 108261011 108279010(rasgrp2)
IFU: 128604189 128622217(rasgrp2)
PHYP: 113541611 113545782
SMEO: 124381478 124398230(rasgrp2)
TFD: 113635487 113648807(rasgrp2)
TVC: 132841760 132859715(rasgrp2)
AMEX: 103025965 103046990
CMAO: 118816665 118820318(rasgrp2)
EEE: 113585260(rasgrp2)
CHAR: 105895053(rasgrp2) 105895414
TRU: 101074408(rasgrp2)
TFS: 130522868
TNG: GSTEN00001427G001
LCO: 104924060(rasgrp2)
NCC: 104942268
TBEN: 117487710
CGOB: 115023498(rasgrp2)
PGEO: 117463895
GACU: 117542718
EMAC: 134875712
ELY: 117272648
EFO: 125883513
PLEP: 121962248
SLUC: 116042255
ECRA: 117935227
ESP: 116707059 116707140
PFLV: 114545322(rasgrp2)
GAT: 120822490
PPUG: 119221651
AFB: 129093774
CLUM: 117747422
PSWI: 130212035
MSAM: 119912454
SCHU: 122869789
CUD: 121504388
ALAT: 119027385
MZE: 101465816(rasgrp2)
ONL: 100692458(rasgrp2)
OAU: 116315508
OLA: 101160849(rasgrp2)
OML: 112141550
CSAI: 133419935
XMA: 102220152(rasgrp2)
XCO: 114157439(rasgrp2)
XHE: 116732898(rasgrp2)
PRET: 103480179(rasgrp2)
PFOR: 103140618(rasgrp2)
PLAI: 106947368(rasgrp2)
PMEI: 106933619(rasgrp2)
GAF: 122820515
PPRL: 129378255
CVG: 107100159(rasgrp2)
CTUL: 119772167
GMU: 124880556
NFU: 107384786(rasgrp2)
KMR: 108239371
ALIM: 106528460(rasgrp2)
NWH: 119414713
AOCE: 111562544(rasgrp2)
MCEP: 125017774
CSEM: 103391165(rasgrp2)
POV: 109637668(rasgrp2)
SSEN: 122766352
HHIP: 117779283
HSP: 118102494
SMAU: 118300111
LCF: 108882034
SDU: 111226917(rasgrp2)
SLAL: 111654226(rasgrp2)
XGL: 120797441
HCQ: 109511891(rasgrp2)
SSCV: 125985500
SBIA: 133494862
PEE: 133397865
PTAO: 133472924
BPEC: 110168337(rasgrp2)
MALB: 109969412(rasgrp2)
BSPL: 114846438
SJO: 128383738
SASA: 100194852(grp2) 106577535(rasgrp2) 106608563
STRU: 115194151 115198160 115204444
OTW: 112214780 112231180(rasgrp2) 112260063
OMY: 110500698 110510123(rasgrp2) 110531842
OGO: 124007228(rasgrp2) 124007874 124018850
ONE: 115101440 115133630 115138165
OKI: 109873795 109897100 109906582
OKE: 118368668 118384993(rasgrp2) 118392700
SALP: 111955126 111960312 111964340
SNH: 120021813(rasgrp2) 120030628 120049216
CCLU: 121542092(rasgrp2) 121554592 121571119
ELS: 105010908 105020724(rasgrp2)
SFM: 108934392(rasgrp2)
PKI: 111836739 111851985
AANG: 118224367 118235482
PSPA: 121310087
ARUT: 117398603 117967784
PSEX: 120539268
LCM: 102348970(RASGRP2)
HOC: 132836141
LERI: 129694559 129706041
 » show all
Reference
PMID:10918068
  Authors
Clyde-Smith J, Silins G, Gartside M, Grimmond S, Etheridge M, Apolloni A, Hayward N, Hancock JF
  Title
Characterization of RasGRP2, a plasma membrane-targeted, dual specificity Ras/Rap exchange factor.
  Journal
J Biol Chem 275:32260-7 (2000)
DOI:10.1074/jbc.M006087200
  Sequence
[hsa:10235]

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Ontology (3)   
   KEGG BRITE (2)   
   GO (1)   
Pathway (12)   
   KEGG PATHWAY (12)   
Disease (1)   
   KEGG DISEASE (1)   
Gene (1067)   
   KEGG GENES (369)   
   KEGG MGENES (386)   
   RefGene (309)   
   OC (3)   
Literature (1)   
   PubMed (1)   
All databases (1084)   

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