KEGG   ORTHOLOGY: K12406Help
Entry
K12406                      KO                                     
Name
PKLR
Definition
pyruvate kinase isozymes R/L [EC:2.7.1.40]
Pathway
Glycolysis / Gluconeogenesis
Purine metabolism
Pyruvate metabolism
Insulin signaling pathway
Type II diabetes mellitus
Maturity onset diabetes of the young
Module
M00001  
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
M00002  
Glycolysis, core module involving three-carbon compounds
M00049  
Adenine ribonucleotide biosynthesis, IMP => ADP,ATP
M00050  
Guanine ribonucleotide biosynthesis IMP => GDP,GTP
Disease
H01096  
Pyruvate kinase (PK) deficiency
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    K12406  PKLR; pyruvate kinase isozymes R/L
   00620 Pyruvate metabolism
    K12406  PKLR; pyruvate kinase isozymes R/L
  Nucleotide metabolism
   00230 Purine metabolism
    K12406  PKLR; pyruvate kinase isozymes R/L
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    K12406  PKLR; pyruvate kinase isozymes R/L
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    K12406  PKLR; pyruvate kinase isozymes R/L
   04950 Maturity onset diabetes of the young
    K12406  PKLR; pyruvate kinase isozymes R/L
KEGG pathway modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Central carbohydrate metabolism
    M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
     K12406  PKLR; pyruvate kinase isozymes R/L
    M00002  Glycolysis, core module involving three-carbon compounds
     K12406  PKLR; pyruvate kinase isozymes R/L
  Nucleotide and amino acid metabolism
   Purine metabolism
    M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP
     K12406  PKLR; pyruvate kinase isozymes R/L
    M00050  Guanine ribonucleotide biosynthesis IMP => GDP,GTP
     K12406  PKLR; pyruvate kinase isozymes R/L
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.40  pyruvate kinase
     K12406  PKLR; pyruvate kinase isozymes R/L
BRITE hierarchy
Other DBs
Genes
HSA: 
5313(PKLR)
PTR: 
469513(PKLR)
PPS: 
100980055(PKLR)
GGO: 
101129346(PKLR)
PON: 
100435140(PKLR)
MCC: 
719152(PKLR)
MMU: 
18770(Pklr)
RNO: 
24651(Pklr)
CFA: 
490425(PKLR)
AML: 
FCA: 
101088459(PKLR)
BTA: 
539579(PKLR)
SSC: 
100625071
ECB: 
100063608
MDO: 
100022269(PKLR)
SHR: 
100930790(PKLR)
 » show all
TaxonomyKoalaUniProt
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