KEGG   ORTHOLOGY: K12560Help
Entry
K12560                      KO                                     

Name
FCGR2B, CD32
Definition
low affinity immunoglobulin gamma Fc region receptor II-b
Pathway
Phagosome
Osteoclast differentiation
Fc gamma R-mediated phagocytosis
Staphylococcus aureus infection
Tuberculosis
Measles
Disease
H00080  
Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:ko00001]
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc region receptor II-b
 Organismal Systems
  Immune system
   04666 Fc gamma R-mediated phagocytosis
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc region receptor II-b
  Development
   04380 Osteoclast differentiation
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc region receptor II-b
 Human Diseases
  Infectious diseases
   05150 Staphylococcus aureus infection
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc region receptor II-b
   05152 Tuberculosis
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc region receptor II-b
   05162 Measles
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc region receptor II-b
Cellular antigens [BR:ko04090]
 Proteins
  K12560  CD32b, FCGR2B; Fc fragment of IgG, low affinity IIb, receptor for (CD32)
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
2213(FCGR2B)
PTR: 
746456(FCGR2B)
PPS: 
100984838(FCGR2B)
GGO: 
101128757(FCGR2B)
PON: 
100453137(FCGR2B)
MCC: 
720009(FCGR2B)
MCF: 
102139530(FCGR2B)
MMU: 
14130(Fcgr2b)
RNO: 
289211(Fcgr2b)
HGL: 
TUP: 
102500089(FCGR2B)
CFA: 
100856270(FCGR2B)
AML: 
FCA: 
101087550(FCGR2B)
PTG: 
BTA: 
282229(FCGR2B)
BOM: 
PHD: 
CHX: 
SSC: 
613131(FCGR2B)
CFR: 
102516047(FCGR2B)
BACU: 
LVE: 
ECB: 
102150150(FCGR2B)
MYB: 
MYD: 
PALE: 
102893641(FCGR2B)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9232445
  Authors
Sarmay G, Koncz G, Pecht I, Gergely J
  Title
Fc gamma receptor type IIb induced recruitment of inositol and protein phosphatases to the signal transductory complex of human B-cell.
  Journal
Immunol Lett 57:159-64 (1997)
Reference
  Authors
Willcocks LC, Carr EJ, Niederer HA, Rayner TF, Williams TN, Yang W, Scott JA, Urban BC, Peshu N, Vyse TJ, Lau YL, Lyons PA, Smith KG
  Title
A defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosus.
  Journal
Proc Natl Acad Sci U S A 107:7881-5 (2010)

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