KEGG ORTHOLOGY: K12560

ORTHOLOGY: K12560

Entry

K12560                      KO

Symbol

FCGR2B, CD32

Name

low affinity immunoglobulin gamma Fc receptor II-b

Pathway

map04145

Phagosome

map04380

Osteoclast differentiation

map04662

B cell receptor signaling pathway

map04666

Fc gamma R-mediated phagocytosis

map05150

Staphylococcus aureus infection

map05152

Tuberculosis

map05162

Measles

Disease

H00080

Systemic lupus erythematosus

H00361

Malaria

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
09150 Organismal Systems
  09151 Immune system
   04662 B cell receptor signaling pathway
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
   04666 Fc gamma R-mediated phagocytosis
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
09160 Human Diseases
  09172 Infectious disease: viral
   05162 Measles
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
   05152 Tuberculosis
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
Membrane trafficking [BR:ko04131]
Endocytosis
  Phagocytosis
   Fc receptors
    K12560  FCGR2B, CD32; low affinity immunoglobulin gamma Fc receptor II-b
CD molecules [BR:ko04090]
Proteins
  K12560  CD32b, FCGR2B; Fc fragment of IgG, low affinity IIb, receptor for (CD32)

Other DBs

GO:

0019770

Genes

HSA:	2213(FCGR2B)

PTR:

748765

PPS:	100984838(FCGR2B)

GGO:	101128757(FCGR2B) 115932911

PON:	100453137(FCGR2B)

NLE:	101176250(FCGR2B)

HMH:	116473326(FCGR2B)

MCC:	720009(FCGR2B)

MCF:	102139530(FCGR2B)

MNI:	105498217(FCGR2B)

CSAB:

103223672(FCGR2B)

CATY:

105589236(FCGR2B)

PANU:

101011136(FCGR2B)

TGE:	112609495(FCGR2B)

MLEU:

105551011(FCGR2B)

RRO:	104670387(FCGR2B)

RBB:	108542588(FCGR2B)

TFN:	117074577(FCGR2B)

PTEH:

111533804(FCGR2B)

CANG:

105519601(FCGR2B)

CJC:	100412558(FCGR2B)

SBQ:	101039367(FCGR2B)

CIMI:

108293620(FCGR2B) 108302361

CSYR:

103277310(FCGR2B)

MMUR:

105873560(FCGR2B)

LCAT:

123635230

PCOQ:

105806465(FCGR2B)

OGA:	100958885(FCGR2B)

MMU:	14130(Fcgr2b)

MCAL:

110299221

MPAH:

110321728

RNO:	289211(Fcgr2b)

MCOC:

116103280

ANU:	117712635(Fcgr2b)

MUN:	110554428(Fcgr2b)

CGE:

103161893

MAUA:

101844813(Fcgr2b)

PROB:

127223559(Fcgr2b)

PLEU:

114689890(Fcgr2b)

MORG:

121442022 121455099

MFOT:

126511148

AAMP:

119827205(Fcgr2b)

NGI:	103746773(Fcgr2b)

HGL:	101704179(Fcgr2b)

CPOC:

100192391(Fcgr2b)

CCAN:

109693504(Fcgr2b)

DORD:

105996454

DSP:

122109326

PLOP:

125359219(Fcgr2b)

NCAR:

124993135 124993151

MMMA:

107147460

OCU:

100359306

OPI:	101523293(FCGR2B)

TUP:	102500089(FCGR2B)

CFA:	100856270(FCGR2B)

CLUD:

112643042(FCGR2B)

VVP:	112914296(FCGR2B)

VLG:	121472254(FCGR2B)

NPO:	129515369(FCGR2B)

AML:

100479420

UMR:	103658249(FCGR2B)

UAH:	113268760(FCGR2B)

UAR:	123783523(FCGR2B)

MNP:

132025750

MLK:

131814734

NVS:	122918381(FCGR2B)

ORO:	101363428(FCGR2B)

EJU:	114210517(FCGR2B)

ZCA:

113933575

MLX:	118014025(FCGR2B)

NSU:	110588143(FCGR2B)

LWW:	102736172(FCGR2B)

FCA:	101087550(FCGR2B)

PYU:	121020941(FCGR2B)

PBG:

122475591

PVIV:

125155527

LRUF:

124509903

PTG:	102959619(FCGR2B)

PPAD:

109276672(FCGR2B)

PUC:

125925565

AJU:

106986772

HHV:	120241067(FCGR2B)

BTA:	282229(FCGR2B)

BOM:

102273069

BIU:	109578097(FCGR2B)

BBUB:

102394636

BBIS:

104999183(FCGR2B)

CHX:

102186356

OAS:	100192432(FCGR2B)

BTAX:

128044371(FCGR2B)

ODA:

120855416

CCAD:

122430161(FCGR2B)

MBEZ:

129541246(FCGR2B)

SSC:	613131(FCGR2B)

CFR:

102516047

CBAI:

105068021(FCGR2B)

CDK:	105092686 116151293

VPC:

BACU:

BMUS:

LVE:

OOR:

PCAD:

PSIU:

116758779(FCGR2B)

NASI:

112403897(FCGR2B) 112403899

ECB:

102150150

EPZ:	103555970(FCGR2B)

EAI:

MYB:

MYD:

MMYO:

EFUS:

103296486(FCGR2B)

MNA:

107535132

DRO:	112297192(FCGR2B)

SHON:

118979067(FCGR2B)

AJM:	119052404(FCGR2B)

PDIC:

114489494

PHAS:

123818559(FCGR2B)

MMF:	118637095(FCGR2B)

PPAM:

129082081

HAI:	109392296(FCGR2B)

RFQ:	117014583(FCGR2B)

PALE:

PGIG:

PVP:

RAY:

TOD:	119241334(FCGR2B)

SARA:

SETR:

LAV:

TMU:

ETF:	101660247(FCGR2B)

DNM:	101417741(FCGR2B)

MDO:	100015202 100619042(FCGR2B)

GAS:	123243617 123245384

SHR:	100924400(FCGR2B)

AFZ:

PCW:

SCAN:

PMOA:

BBUF:

MZE:	101479608 112430766 112431154

ONL:

102079358

OAU:	116314316 116321146 120436245 120439145

CVG:	107104243 107105095

SASA:

106577810 106608912

SALP:

112070016

ELS:	105006757 114830263

» show all

Reference

PMID:9232445

Authors

Sarmay G, Koncz G, Pecht I, Gergely J

Title

Fc gamma receptor type IIb induced recruitment of inositol and protein phosphatases to the signal transductory complex of human B-cell.

Journal

Immunol Lett 57:159-64 (1997)
DOI:10.1016/S0165-2478(97)00055-2

Sequence

[hsa:2213]

Reference

PMID:20385827

Authors

Willcocks LC, Carr EJ, Niederer HA, Rayner TF, Williams TN, Yang W, Scott JA, Urban BC, Peshu N, Vyse TJ, Lau YL, Lyons PA, Smith KG

Title

A defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosus.

Journal

Proc Natl Acad Sci U S A 107:7881-5 (2010)
DOI:10.1073/pnas.0915133107

Sequence

[hsa:2213]

Reference

PMID:2531080

Authors

Stuart SG, Simister NE, Clarkson SB, Kacinski BM, Shapiro M, Mellman I

Title

Human IgG Fc receptor (hFcRII; CD32) exists as multiple isoforms in macrophages, lymphocytes and IgG-transporting placental epithelium.

Journal

EMBO J 8:3657-66 (1989)
DOI:10.1002/j.1460-2075.1989.tb08540.x

Sequence

[hsa:2213]

All links

Ontology (4)   
   KEGG BRITE (3)   
   GO (1)   
Pathway (14)   
   KEGG PATHWAY (14)   
Disease (2)   
   KEGG DISEASE (2)   
Drug (1)   
   KEGG DRUG (1)   
Gene (170)   
   KEGG GENES (165)   
   RefGene (2)   
   OC (3)   
Literature (3)   
   PubMed (3)   
All databases (194)   

Download RDF

DBGET integrated database retrieval system