KEGG ORTHOLOGY: K13524

ORTHOLOGY: K13524

Entry

K13524 KO

Name

ABAT

Definition

4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase [EC:2.6.1.19 2.6.1.22]

Pathway

ko00250	Alanine, aspartate and glutamate metabolism
ko00280	Valine, leucine and isoleucine degradation
ko00410	beta-Alanine metabolism
ko00640	Propanoate metabolism
ko00650	Butanoate metabolism
ko04727	GABAergic synapse

Module

M00027

GABA (gamma-Aminobutyrate) shunt

Disease

H01257

GABA-transaminase deficiency

Brite

KEGG Orthology (KO) [BR:ko00001]
Metabolism
  Carbohydrate metabolism
   00640 Propanoate metabolism
    K13524  ABAT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase
   00650 Butanoate metabolism
    K13524  ABAT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase
  Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    K13524  ABAT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase
   00280 Valine, leucine and isoleucine degradation
    K13524  ABAT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase
  Metabolism of other amino acids
   00410 beta-Alanine metabolism
    K13524  ABAT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase
Organismal Systems
  Nervous system
   04727 GABAergic synapse
    K13524  ABAT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase
KEGG pathway modules [BR:ko00002]
Pathway module
  Nucleotide and amino acid metabolism
   Other amino acid metabolism
    M00027  GABA (gamma-Aminobutyrate) shunt
     K13524  ABAT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase
Enzymes [BR:ko01000]
2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.19  4-aminobutyrate---2-oxoglutarate transaminase
     K13524  ABAT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase
    2.6.1.22  (S)-3-amino-2-methylpropionate transaminase
     K13524  ABAT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase
Amino acid related enzymes [BR:ko01007]
Aminotransferase (transaminase)
  Class III
   K13524  ABAT; 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase

Other DBs

RN:

R00908 R01648 R04188

COG:

COG0160

GO:

0003867 0047298

Genes

HSA:	18(ABAT)
PTR:	453903(ABAT)
PPS:	100983021(ABAT)
GGO:	101148531(ABAT)
PON:	100174312(ABAT)
MCC:	714017(ABAT)
MMU:	268860(Abat)
RNO:	81632(Abat)
CFA:	479856(ABAT)
AML:	100469592(ABAT)
FCA:	101089064(ABAT)
BTA:	280969(ABAT)
SSC:	397500(ABAT)
ECB:	100051470(ABAT)
MDO:	100026169
SHR:	100922618(ABAT)
OAA:	100075373
GGA:	416642(ABAT)
MGP:	100549381
TGU:	100224473(ABAT)
ACS:	100564208
XLA:	398751(abat) 399028
XTR:	100158654(abat)
DRE:	378968(abat)
TRU:	101073598
OLA:	101158322
BFO:	BRAFLDRAFT_60229
CIN:	100177324
SPU:	577656(abat)
DME:	Dmel_CG7433
DAN:	Dana_GF10831
DER:	Dere_GG13352
DPE:	Dper_GL11898
DSE:	Dsec_GM14750
DSI:	Dsim_GD12233
DWI:	Dwil_GK20289
DYA:	Dyak_GE22444
DGR:	Dgri_GH17185
DMO:	Dmoj_GI13950
DVI:	Dvir_GJ13734
AGA:	AgaP_AGAP006966
AAG:	AaeL_AAEL012609
CQU:	CpipJ_CPIJ008729
AME:	408955
NVI:	100121289(NV12218)
TCA:	100142274 656992
API:	100164587
PHU:	Phum_PHUM320310
ISC:	IscW_ISCW019639
CEL:	CELE_K04D7.3(gta-1)
CBR:	CBG03400(Cbr-gta-1)
BMY:	Bm1_27120
NVE:	NEMVE_v1g227385
HMG:	100205601
TAD:	TRIADDRAFT_60215
AQU:	100636151
OLU:	OSTLU_38108
OTA:	Ot10g02220
CME:	CMR117C
SCE:	YGR019W(UGA1)
AGO:	AGOS_AGL050C
KLA:	KLLA0F20548g
LTH:	KLTH0H08976g
PPA:	PAS_chr2-1_0107 PAS_chr4_0677
VPO:	Kpol_1064p60
ZRO:	ZYRO0A11990g
CGR:	CAGL0D04026g
NCS:	NCAS_0A01920(NCAS0A01920)
NDI:	NDAI_0D03850(NDAI0D03850)
TPF:	TPHA_0K01360(TPHA0K01360)
TDL:	TDEL_0D02960(TDEL0D02960)
KAF:	KAFR_0F03700(KAFR0F03700)
DHA:	DEHA2C16324g DEHA2F09306g
PIC:	PICST_46781(UGA1.2) PICST_54153(UGA1.1)
PGU:	PGUG_01516 PGUG_03850
LEL:	LELG_01027 LELG_01273
CAL:	CaO19.8421(UGA11) CaO19.8474(UGA12) CaO19.854(UGA12)
CTP:	CTRG_01206 CTRG_01571
CDU:	CD36_18350 CD36_18820
COT:	CORT_0A10390 CORT_0A10730
YLI:	YALI0E18238g
CLU:	CLUG_01091 CLUG_05140
NCR:	NCU08998
SMP:	SMAC_01953
PAN:	PODANSg5164
TTT:	THITE_2118631
MTM:	MYCTH_2304900
MGR:	MGG_01662
FGR:	FG05554.1
NHE:	NECHADRAFT_62794
VAL:	VDBG_09333
SSL:	SS1G_07083
ANI:	AN2248.2
NFI:	NFIA_036430
AFM:	AFUA_5G06680
AOR:	AOR_1_382114(AO090701000206)
ANG:	ANI_1_122154(An17g00910)
AFV:	AFLA_056670
ACT:	ACLA_010000
PCS:	Pc21g17880
CIM:	CIMG_05995
CPW:	CPC735_025780
PBL:	PAAG_00468
URE:	UREG_04369
ABE:	ARB_07120
TVE:	TRV_04898
AJE:	HCAG_08375
PNO:	SNOG_01821
PTE:	PTT_06674
ZTR:	MYCGRDRAFT_36524
TML:	GSTUM_00009671001
SPO:	SPAC19D5.07(uga1)
CNE:	CND02040 CNE01830
CNB:	CNBD4320 CNBE1800
CGI:	CGB_D4450W CGB_E2380C
UMA:	UM01080.1
PGR:	PGTG_07214
NGR:	NAEGRDRAFT_37208
DDI:	DDB_G0268104(gabT)
DPP:	DICPUDRAFT_47017
PIF:	PITG_05225
SCL:	sce9194

» show all

Reference

PMID:10989446

Authors

Tamaki N, Sakata SF, Matsuda K

Title

Purification, properties, and sequencing of aminoisobutyrate aminotransferases from rat liver.

Journal

Methods Enzymol 324:376-89 (2000)

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Ontology (12)   
   KEGG BRITE (9)   
   GO (2)   
   COG (1)   
Pathway (354)   
   KEGG PATHWAY (14)   
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Disease (1)   
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Drug (5)   
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Gene (203)   
   KEGG GENES (138)   
   KEGG DGENES (13)   
   KEGG EGENES (41)   
   KEGG MGENES (11)   
Protein sequence (118)   
   UniProt (118)   
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