KEGG   ORTHOLOGY: K15759Help
Entry
K15759                      KO                                     

Name
IMPAD1, IMPA3
Definition
inositol monophosphatase 3 [EC:3.1.3.25 3.1.3.7]
Pathway
Inositol phosphate metabolism
Sulfur metabolism
Phosphatidylinositol signaling system
Module
M00131  
Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    K15759  IMPAD1, IMPA3; inositol monophosphatase 3
  Energy metabolism
   00920 Sulfur metabolism
    K15759  IMPAD1, IMPA3; inositol monophosphatase 3
 Environmental Information Processing
  Signal transduction
   04070 Phosphatidylinositol signaling system
    K15759  IMPAD1, IMPA3; inositol monophosphatase 3
KEGG modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Lipid metabolism
    M00131  Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol
     K15759  IMPAD1, IMPA3; inositol monophosphatase 3
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.7  3'(2'),5'-bisphosphate nucleotidase
     K15759  IMPAD1, IMPA3; inositol monophosphatase 3
    3.1.3.25  inositol-phosphate phosphatase
     K15759  IMPAD1, IMPA3; inositol monophosphatase 3
BRITE hierarchy
Other DBs
Genes
HSA: 
54928(IMPAD1)
PTR: 
464188(IMPAD1)
PPS: 
100991995(IMPAD1)
GGO: 
101126664(IMPAD1)
PON: 
100453710(IMPAD1)
NLE: 
100602566(IMPAD1)
MCC: 
696893(IMPAD1)
MCF: 
102127188(IMPAD1)
CJC: 
100395037(IMPAD1)
MMU: 
242291(Impad1)
RNO: 
312952(Impad1)
CGE: 
100756245(Impad1)
NGI: 
103734175(Impad1)
HGL: 
101722322(Impad1)
OCU: 
100343037(IMPAD1)
TUP: 
102471602(IMPAD1)
CFA: 
477890(IMPAD1)
AML: 
UMR: 
103677505(IMPAD1)
FCA: 
101098356(IMPAD1)
PTG: 
102950783(IMPAD1)
BTA: 
532797(IMPAD1)
BOM: 
102278852(IMPAD1)
PHD: 
CHX: 
102187243(IMPAD1)
OAS: 
101109546(IMPAD1)
SSC: 
100156925(IMPAD1)
CFR: 
102505980(IMPAD1)
BACU: 
103016546(IMPAD1)
LVE: 
103077117(IMPAD1)
ECB: 
100067414(IMPAD1)
MYB: 
102240640(IMPAD1)
MYD: 
102752696(IMPAD1)
PALE: 
102884282(IMPAD1)
MDO: 
100022402(IMPAD1)
SHR: 
OAA: 
100083240(IMPAD1)
GGA: 
421132(IMPAD1)
MGP: 
APLA: 
101792028(IMPAD1)
TGU: 
FAB: 
101819036(IMPAD1)
PHI: 
102102546(IMPAD1)
FPG: 
101913553(IMPAD1)
FCH: 
102056114(IMPAD1)
CLV: 
102088560(IMPAD1)
ASN: 
AMJ: 
102561192(IMPAD1)
PSS: 
102447509(IMPAD1)
CMY: 
102935218(IMPAD1)
ACS: 
PBI: 
XLA: 
414458(impad1)
XTR: 
548969(impad1)
DRE: 
641570(impad1)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
CIN: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
CEL: 
CELE_Y6B3B.5(Y6B3B.5)
CBR: 
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
NVE: 
HMG: 
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Vissers LE, Lausch E, Unger S, Campos-Xavier AB, Gilissen C, Rossi A, Del Rosario M, Venselaar H, Knoll U, Nampoothiri S, Nair M, Spranger J, Brunner HG, Bonafe L, Veltman JA, Zabel B, Superti-Furga A
  Title
Chondrodysplasia and abnormal joint development associated with mutations in IMPAD1, encoding the Golgi-resident nucleotide phosphatase, gPAPP.
  Journal
Am J Hum Genet 88:608-15 (2011)
Reference
  Authors
Caldwell KK, Sosa M, Buckley CT
  Title
Identification of mitogen-activated protein kinase docking sites in enzymes that  metabolize phosphatidylinositols and inositol phosphates.
  Journal
Cell Commun Signal 4:2 (2006)

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