KEGG ORTHOLOGY: K16027

ORTHOLOGY: K16027

Entry

K16027                      KO

Symbol

asm16

Name

methoxymalonate biosynthesis protein

Pathway

map01051

Biosynthesis of ansamycins

map01052

Type I polyketide structures

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01052 Type I polyketide structures
    K16027  asm16; methoxymalonate biosynthesis protein
   01051 Biosynthesis of ansamycins
    K16027  asm16; methoxymalonate biosynthesis protein
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K16027  asm16; methoxymalonate biosynthesis protein
Polyketide biosynthesis proteins [BR:ko01008]
Polyketide tailoring proteins
  Others
   K16027  asm16; methoxymalonate biosynthesis protein

Genes

MBAI:

MB901379_02748

NTP:	CRH09_20585

SGRF:

SGFS_005670 SGFS_014210

SCB:	SCAB_83971

SVL:	Strvi_5873 Strvi_6778

SRC:	M271_37840 M271_50140

SMAL:

SMALA_0861 SMALA_1269

SSOI:

I1A49_00850 I1A49_07810 I1A49_09830

SBH:	SBI_09658(ozmB)

SCW:	TU94_03075 TU94_30680

SAMB:

SAM23877_5603(srm34)

SCZ:	ABE83_03035

SLE:	sle_62780(sle_62780)

STRT:

A8713_28290

SCLF:

BB341_27685

SGS:	AVL59_10150

SAUO:

BV401_01100 BV401_08120 BV401_10130

SSIA:

A7J05_02385

SALJ:

SMD11_1673

SGD:	ELQ87_38745

SQZ:	FQU76_00580 FQU76_32225

SKA:	CP970_02190

SCAV:

CVT27_30490

SRIM:

CP984_12635

SSUB:

CP968_05695

STSU:

B7R87_00470 B7R87_01715 B7R87_31525

SGX:	H4W23_35905

SSPB:

CP982_14310

SHK:	J2N69_35930

SCAE:

IHE65_08965

SANT:

QR300_33410

SOV:	QZH56_33505

KSK:	KSE_73520(bfmE)

KAB:	B7C62_33105

KIS:	HUT16_05325 HUT16_33215

STRH:

GXP74_17975 GXP74_23575

NAKE:

KGD83_23280

SAIU:

J4H86_01040

AMAZ:

LUW76_46595

SACC:

EYD13_07695 EYD13_10145

AMD:

AMN:

AMM:

AMZ:

AMYB:

AORI:

APRT:

APRE:

AMI:	Amir_3188 Amir_3282

SESP:

BN6_35440

SSYI:

EKG83_24525

KUT:	JJ691_05520

KPHY:

AOZ06_39675

ACTI:

UA75_16770

ACTA:

C1701_23335 C1701_25715

UME:	RM788_50520

MTUA:

MICH:

MCAB:

ACTN:

ACTR:

PLK:	CIK06_12145

PSUU:

Psuf_000480

» show all

Reference

PMID:17076505

Authors

Wenzel SC, Williamson RM, Grunanger C, Xu J, Gerth K, Martinez RA, Moss SJ, Carroll BJ, Grond S, Unkefer CJ, Muller R, Floss HG

Title

On the biosynthetic origin of methoxymalonyl-acyl carrier protein, the substrate for incorporation of "glycolate" units into ansamitocin and soraphen A.

Journal

J Am Chem Soc 128:14325-36 (2006)
DOI:10.1021/ja064408t

Reference

PMID:12060743

Authors

Yu TW, Bai L, Clade D, Hoffmann D, Toelzer S, Trinh KQ, Xu J, Moss SJ, Leistner E, Floss HG

Title

The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum.

Journal

Proc Natl Acad Sci U S A 99:7968-73 (2002)
DOI:10.1073/pnas.092697199

Sequence

[apre:CNX65_16220]

All links

Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Gene (81)   
   KEGG GENES (80)   
   OC (1)   
Literature (2)   
   PubMed (2)   
All databases (89)   

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