KEGG   ORTHOLOGY: K16342Help
Entry
K16342                      KO                                     

Name
PLA2G4, CPLA2
Definition
cytosolic phospholipase A2 [EC:3.1.1.4]
Pathway
Glycerophospholipid metabolism
Ether lipid metabolism
Arachidonic acid metabolism
Linoleic acid metabolism
alpha-Linolenic acid metabolism
MAPK signaling pathway
Ras signaling pathway
Vascular smooth muscle contraction
VEGF signaling pathway
Platelet activation
Fc epsilon RI signaling pathway
Glutamatergic synapse
Serotonergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
GnRH signaling pathway
Ovarian steroidogenesis
Oxytocin signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Lipid metabolism
   00564 Glycerophospholipid metabolism
    K16342  PLA2G4, CPLA2; cytosolic phospholipase A2
   00565 Ether lipid metabolism
    K16342  PLA2G4, CPLA2; cytosolic phospholipase A2
   00590 Arachidonic acid metabolism
    K16342  PLA2G4, CPLA2; cytosolic phospholipase A2
   00591 Linoleic acid metabolism
    K16342  PLA2G4, CPLA2; cytosolic phospholipase A2
   00592 alpha-Linolenic acid metabolism
    K16342  PLA2G4, CPLA2; cytosolic phospholipase A2
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K16342  PLA2G4, CPLA2; cytosolic phospholipase A2
   04010 MAPK signaling pathway
    K16342  PLA2G4, CPLA2; cytosolic phospholipase A2
   04370 VEGF signaling pathway
    K16342  PLA2G4, CPLA2; cytosolic phospholipase A2
 Organismal Systems
  Immune system
   04611 Platelet activation
    K16342  PLA2G4, CPLA2; cytosolic phospholipase A2
   04664 Fc epsilon RI signaling pathway
    K16342  PLA2G4, CPLA2; cytosolic phospholipase A2
  Endocrine system
   04912 GnRH signaling pathway
    K16342  PLA2G4, CPLA2; cytosolic phospholipase A2
   04913 Ovarian Steroidogenesis
    K16342  PLA2G4, CPLA2; cytosolic phospholipase A2
   04921 Oxytocin signaling pathway
    K16342  PLA2G4, CPLA2; cytosolic phospholipase A2
  Circulatory system
   04270 Vascular smooth muscle contraction
    K16342  PLA2G4, CPLA2; cytosolic phospholipase A2
  Nervous system
   04724 Glutamatergic synapse
    K16342  PLA2G4, CPLA2; cytosolic phospholipase A2
   04726 Serotonergic synapse
    K16342  PLA2G4, CPLA2; cytosolic phospholipase A2
   04730 Long-term depression
    K16342  PLA2G4, CPLA2; cytosolic phospholipase A2
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K16342  PLA2G4, CPLA2; cytosolic phospholipase A2
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.4  phospholipase A2
     K16342  PLA2G4, CPLA2; cytosolic phospholipase A2
BRITE hierarchy
Other DBs
Genes
HSA: 
100137049(PLA2G4B) 123745(PLA2G4E) 255189(PLA2G4F) 283748(PLA2G4D) 5321(PLA2G4A) 8605(PLA2G4C) 8681(JMJD7-PLA2G4B)
PTR: 
100610135(PLA2G4D) 453356(PLA2G4F) 453706 467664(PLA2G4E) 468935(PLA2G4C) 469617(PLA2G4A) 739598(PLA2G4B) 739798(PLA2G4B) 740368(PLA2G4B) 747584(PLA2G4B) 748705(PLA2G4B) 749457(PLA2G4B)
PPS: 
100978248(PLA2G4C) 100984773(PLA2G4A) 100986585(PLA2G4F) 100986912(PLA2G4D) 100987249(PLA2G4E)
GGO: 
101126764(PLA2G4C) 101130728(PLA2G4B) 101137812(PLA2G4E) 101138793(PLA2G4F) 101142484 101142840(PLA2G4D) 101147399(PLA2G4A)
PON: 
100173125(PLA2G4A) 100434495(PLA2G4C) 100447631(PLA2G4B) 100448616(PLA2G4F) 100454614(PLA2G4E) 100454977(PLA2G4D)
MCC: 
100533113(PLA2G4B) 707592(PLA2G4D) 707690(PLA2G4F) 716635(PLA2G4A) 718510(PLA2G4C)
MCF: 
102142596(PLA2G4C) 102143026(PLA2G4B) 102143695(PLA2G4A) 102143812(PLA2G4E) 102144463(PLA2G4D) 102146081(PLA2G4F)
MMU: 
18783(Pla2g4a) 211429(Pla2g4b) 232889(Pla2g4c) 271844(Pla2g4f) 329502(Pla2g4e) 78390(Pla2g4d)
RNO: 
24653(Pla2g4a) 296091(Pla2g4e) 311341(Pla2g4b) 691810(Pla2g4c) 691813 691905(Pla2g4d) 691907(Pla2g4f)
CGE: 
HGL: 
101703792(Pla2g4b) 101704061(Pla2g4a) 101705849(Pla2g4e) 101706202(Pla2g4f) 101713091(Pla2g4c) 101717491(Pla2g4d)
TUP: 
102470223(PLA2G4E) 102470647(PLA2G4F) 102471767(PLA2G4D) 102472618(PLA2G4B) 102473333(PLA2G4C) 102477396
CFA: 
480048(PLA2G4A) 487512(PLA2G4B) 487514(PLA2G4E) 487515(PLA2G4F) 608811(PLA2G4D)
AML: 
100469987(PLA2G4F) 100470240(PLA2G4D) 100470490(PLA2G4E) 100482619
FCA: 
101082033(PLA2G4A) 101082574(PLA2G4F) 101082828(PLA2G4E) 101082829(PLA2G4D) 101083342(JMJD7)
PTG: 
102948969(PLA2G4A) 102959018(PLA2G4B) 102959667(PLA2G4E) 102959937(PLA2G4F) 102964036(PLA2G4D)
BTA: 
505485(PLA2G4B) 522866(PLA2G4F) 525072(PLA2G4A) 526364(PLA2G4E) 531209(PLA2G4D)
BOM: 
102271639(PLA2G4A) 102282019(PLA2G4B) 102282579(PLA2G4E) 102282862(PLA2G4D) 102283142(PLA2G4F)
PHD: 
102326509(PLA2G4A) 102339197(PLA2G4F) 102339558(PLA2G4D) 102339921(PLA2G4E) 102340632(PLA2G4B)
CHX: 
102175216(PLA2G4B) 102178930(PLA2G4A) 102187595(PLA2G4E) 102187867(PLA2G4D) 102188141(PLA2G4F)
SSC: 
100152927(PLA2G4B) 100513834(PLA2G4F) 100514811(PLA2G4E) 100520687(PLA2G4A) 100523297 100737865 100738586
CFR: 
102507142(PLA2G4D) 102509341(PLA2G4A) 102516599(PLA2G4B) 102517096(PLA2G4E) 102517351(PLA2G4F)
ECB: 
100033889(PLA2G4A) 100071016(PLA2G4F) 100071025(PLA2G4D) 100071038(PLA2G4E) 100071062(PLA2G4B)
MYB: 
102239879(PLA2G4B) 102241902(PLA2G4D) 102242502(PLA2G4F) 102259120(PLA2G4A) 102260953(PLA2G4E)
MYD: 
102754320(PLA2G4D) 102754611(PLA2G4E) 102771796(PLA2G4F) 102772466(PLA2G4B) 102774327(PLA2G4A)
PALE: 
102883421(PLA2G4F) 102883684(PLA2G4E) 102886310(PLA2G4A) 102887778(PLA2G4D)
MDO: 
100009808(PLA2G4E) 100029998 100620032(PLA2G4D)
SHR: 
100913647 100914602(PLA2G4B) 100917893(PLA2G4D) 100918158(PLA2G4F) 100927005(PLA2G4C) 100927268(PLA2G4A)
OAA: 
GGA: 
MGP: 
TGU: 
FAB: 
PHI: 
APLA: 
FPG: 
FCH: 
CLV: 
ASN: 
PSS: 
CMY: 
ACS: 
XLA: 
380561(pla2g4a)
XTR: 
100145731(pla2g4a) 100485430(pla2g4d) 100497525(pla2g4f)
DRE: 
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
BFO: 
CIN: 
NVE: 
NCR: 
SMP: 
PAN: 
TTT: 
MTM: 
MGR: 
FGR: 
NHE: 
TRE: 
VAL: 
SSL: 
BFU: 
ANI: 
AFM: 
AOR: 
AOR_1_828014(AO090026000448)
ANG: 
ANI_1_2450024(An02g04040)
AFV: 
ACT: 
NFI: 
PCS: 
CIM: 
CPW: 
PBL: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
ZTR: 
TML: 
UMA: 
MGL: 
GTT: 
DPB: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Schaloske RH, Dennis EA
  Title
The phospholipase A2 superfamily and its group numbering system.
  Journal
Biochim Biophys Acta 1761:1246-59 (2006)
Reference
  Authors
Ghosh M, Loper R, Gelb MH, Leslie CC
  Title
Identification of the expressed form of human cytosolic phospholipase A2beta (cPLA2beta): cPLA2beta3 is a novel variant localized to mitochondria and early endosomes.
  Journal
J Biol Chem 281:16615-24 (2006)

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