Entry
Symbol
ARFGEF, BIG
Name
brefeldin A-inhibited guanine nucleotide-exchange protein
Pathway
Disease
H00270 Periventricular nodular heterotopia
H02685 Developmental delay with neuropsychiatric disorders
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
K18442 ARFGEF, BIG; brefeldin A-inhibited guanine nucleotide-exchange protein
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking
K18442 ARFGEF, BIG; brefeldin A-inhibited guanine nucleotide-exchange protein
Membrane trafficking [BR:ko04131 ]
Endosome - Golgi transport
Arf GTPases and associated proteins
Arf GTPase associated proteins
K18442 ARFGEF, BIG; brefeldin A-inhibited guanine nucleotide-exchange protein
BRITE hierarchy
Other DBs
Genes
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Taxonomy UniProt
Reference
Authors
Saeki N, Tokuo H, Ikebe M
Title
BIG1 is a binding partner of myosin IXb and regulates its Rho-GTPase activating protein activity.
Journal
Sequence
Reference
Authors
Shin HW, Morinaga N, Noda M, Nakayama K
Title
BIG2, a guanine nucleotide exchange factor for ADP-ribosylation factors: its localization to recycling endosomes and implication in the endosome integrity.
Journal
Sequence