KEGG ORTHOLOGY: K22443

ORTHOLOGY: K22443

Entry

K22443                      KO

Symbol

cntA

Name

carnitine monooxygenase subunit [EC:1.14.13.239]

Brite

KEGG Orthology (KO) [BR:ko00001]
09190 Not Included in Pathway or Brite
  09191 Unclassified: metabolism
   99980 Enzymes with EC numbers
    K22443  cntA; carnitine monooxygenase subunit
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.239  carnitine monooxygenase
     K22443  cntA; carnitine monooxygenase subunit

Other DBs

COG:

COG4638

Genes

ECO:	b1802(yeaW)

ECJ:	JW5294(yeaW)

ECD:	ECDH10B_1940(yeaW)

EBW:	BWG_1615(yeaW)

ECOK:

ECMDS42_1476(yeaW)

ECOC:

C3026_10270

ECE:	Z2845(yeaW)

ECS:	ECs_2511(yeaW)

ECF:	ECH74115_2528

ETW:	ECSP_2374(yeaW)

ELX:	CDCO157_2345

EOI:	ECO111_2308(yeaW)

EOJ:	ECO26_2571(yeaW)

EOH:	ECO103_1991(yeaW)

ECOO:

ECRM13514_2305(yeaW)

ECOH:

ECRM13516_2207(yeaW)

ESL:

O3K_10940

ESO:

O3O_14685

ESM:

O3M_10910

ECK:	EC55989_1975(yeaW)

EOK:	G2583_2249(yeaW)

ELR:	ECO55CA74_10820

ELH:

ETEC_1834

ECW:	EcE24377A_2028

EUN:	UMNK88_2272

ECOA:

APECO78_12810

ECX:	EcHS_A1890

ECM:	EcSMS35_1386

ECY:

ECSE_1976

ECR:	ECIAI1_1871(yeaW)

EUM:	ECUMN_2094(yeaW)

ECT:	ECIAI39_1251(yeaW)

EOC:	CE10_2084(yeaW)

EBR:	ECB_01772(yeaW)

ECOB:

C3029_13430

EBL:	ECD_01772(yeaW)

EBE:	B21_01760(yeaW)

EBD:

ECBD_1840

ELO:	EC042_1967

ECL:	EcolC_1831

EKO:	EKO11_1971

EKF:	KO11_13705(yeaW)

EDH:	EcDH1_1841

EDJ:	ECDH1ME8569_1746(yeaW)

ELW:	ECW_m1971(yeaW)

ELL:	WFL_09685(yeaW)

ELP:	P12B_c1279(yeaW)

ECOL:

LY180_09385

EAL:	EAKF1_ch4249c

ESZ:	FEM44_23900(yeaW)

ERUY:

OSH18_03700(yeaW)

SFV:

SFV_1427

SFE:	SFxv_1614(yeaW)

SFN:

SFy_2041

SFS:

SFyv_2093

SFT:	NCTC1_01527(yeaW)

SSN:	SSON_1359(yeaW)

SBO:	SBO_1286(yeaW)

SBC:	SbBS512_E2062

SDY:	SDY_1706(yeaW)

SHQ:	A0259_13095

KPN:

KPN_01013

KPU:

KP1_1996

KPM:	KPHS_18860

KPP:

A79E_3220

KPH:	KPNIH24_19070

KPZ:	KPNIH27_08915

KPV:	KPNIH29_09445

KPW:	KPNIH30_09960

KPY:	KPNIH31_09335

KPG:	KPNIH32_09800

KPC:	KPNIH10_09455

KPQ:	KPR0928_09625

KPT:	VK055_1464

KPO:	KPN2242_08125

KPR:	KPR_3509(yeaW)

KPJ:

N559_3274

KPI:	D364_05270

KPA:	KPNJ1_03516

KPS:	KPNJ2_03505

KPX:	PMK1_03353(cbdA_1)

KPB:	FH42_00920

KPNE:

KU54_016700

KPNU:

LI86_17010

KPNK:

BN49_2100(yeaW)

KVA:

Kvar_3366

KPE:

KPK_3547

KVD:	KR75_17235

KVQ:	SP68_23615

KQU:	AVR78_13890

EAE:

EAE_15885

EAR:

CCG30729

KAR:	LGL98_16160

CBRA:

A6J81_06350

CYO:	CD187_10205

CPOT:

FOB25_21785

CFQ:	C2U38_10325

CIF:	AL515_13735

CPAR:

CUC49_09460

CARS:

E1B03_15695

CENS:

P2W74_13725(yeaW)

EBT:	EBL_c14120(yeaW)

ESC:	Entcl_2811

KLE:	AO703_08135

EBU:	CUC76_06225

YPE:

YPO2493

YPA:

YPA_1989

YPN:

YPN_2088

YPM:	YP_2308(hcaA11)

YPP:	YPDSF_1905

YPG:	YpAngola_A1753

YPZ:

YPZ3_2136

YPT:	A1122_13670

YPD:

YPX:

YPW:

YPJ:

YPV:

YPL:

YPS:

YPO:

YPI:	YpsIP31758_1516

YPY:

YPB:

YPQ:

YPU:

YPR:

YPC:

YPF:

YSI:	BF17_22115

SMAR:

SM39_3539

SMAC:

SMDB11_3351

SMW:	SMWW4_v1c40530(yeaW)

SLQ:	M495_20620

SERF:

SERS:

SSUR:

SURI:

SNEV:

XNE:	XNC1_0564(yeaW)

XNM:	XNC2_0552(yeaW)

XHO:	A9255_13420

XBU:	HGO23_00090

PSI:

PSX:

PSTA:

PTHA:

PRG:	RB151_006210(antA)

PHEI:

NCTC12003_00623(antA)

PRQ:	CYG50_12990

PVC:	G3341_02920

PMAG:

JI723_03315

PHAG:

PZ638_02930

VEJ:	VEJY3_06980

VTA:	A3368(yeaW)

SKS:	FCN78_12235

PRE:	PCA10_47190

PFUW:

KF707C_22480

PCQ:	PcP3B5_28790(antA_2) PcP3B5_38810(antA_4)

PMUI:

G4G71_17985 G4G71_25700

PNT:	G5B91_08330 G5B91_13990

PPG:	PputGB1_2194 PputGB1_3019

PPUT:

L483_19325

PPUN:

PP4_21090(yeaW)

PMOL:

PMOS:

PAZO:

PEN:

PKC:	PKB_3452(yeaW)

PALK:

PSAKL28_33290

PRH:	LT40_18970

PSEC:

CCOS191_3070(yeaW)

PSET:

THL1_4425

PKE:	DLD99_18940

PLAL:

FXN65_16245 FXN65_21225

PQI:	KH389_11850

PMAM:

KSS90_10600

PORY:

EJA05_15695

PCAV:

D3880_16585

PIZ:	LAB08_R21280 LAB08_R42020

PSIH:

LOY51_16045

PNB:	NK667_05590

PSOA:

PSm6_00840(yeaW)

PKK:	QQ992_10620

PTRL:

OU419_07450

ACB:

A1S_0852

ABC:	ACICU_00805

ABN:

AB57_0900

ABB:	ABBFA_02737(antA_3)

ABX:

ABK1_0843

ABZ:	ABZJ_00846

ABR:	ABTJ_02959

ABD:	ABTW07_0836

ABH:

M3Q_1051

ABAD:

ABD1_08020

ABJ:	BJAB07104_00856

ABAB:

BJAB0715_00841

ABAJ:

BJAB0868_00865

ABK:	LX00_04265

ABAU:

IX87_01895

ABAA:

IX88_06250

ABW:	BL01_07960

ABAL:

ABLAC_30030

ACC:	BDGL_000119(yeaW)

ANO:	RR32_13935

ALC:	OTEC02_14670

ASEI:

I8T81_14755

ACD:	AOLE_15430

ACW:	A0J50_13240

ADV:	DJ533_02965

AGU:

AS4_16360

AUG:

URS_2186

ADS:	FPL17_02690

ABER:

BSR55_16270

ACHI:

CDG60_06700 CDG60_12935

AGYL:

APRL:

ACOI:

AVIV:

ACIE:

CSA:

CCAG:

HBE:

MSEC:

MRZ:	KDW95_05545

VMS:	LVJ82_12455

CCAH:

DWG20_05530 DWG20_12035

CRZ:	D1345_05785

CHAE:

CH06BL_12580

AMAH:

DLM_3015

AQS:	DKK66_11975

RPJ:	N234_32220

REH:	H16_B2129(h16_B2129)

CNC:	CNE_2c20930

CUH:	BJN34_33200

REU:	Reut_B5836

CTI:	RALTA_B1830

CCUP:

BKK81_31880

CUP:	BKK80_24470

CUU:	BKK79_29745

COX:	E0W60_04285

CUK:	KB879_15860

CNAN:

A2G96_22370 A2G96_28630

BUR:	Bcep18194_B0529 Bcep18194_C7702

BCEN:

DM39_6553

BMJ:	BMULJ_05507

BMU:

BMK:

BMUL:

BPSL:

BANN:

BAEN:

L3V59_26400 L3V59_38650

PACS:

FAZ98_33730

PPAI:

E1956_32080 E1956_34365

CABA:

SBC2_60630(yeaW_3)

TVL:	FAZ95_07705

ASW:	CVS48_20825

ACHB:

DVB37_11465

TMJ:	P0M04_20640

MCI:	Mesci_5764

MOP:	Mesop_6341

MAM:	Mesau_05813

MAMO:

A6B35_29595

LABR:

CHH27_14540

LABP:

FJ695_25375

RPOP:

K1718_06460 K1718_08110

SIL:

SPO1590

RUA:	D1823_09020 D1823_12800

RUT:	FIU92_00680(bedC1) FIU92_18595(antA)

RCON:

K3740_13680

OAR:	OA238_c45000

LMD:	METH_03745

LEJ:	ETW24_04600

LEV:	ETW23_15600

LCAE:

K3721_03885

SULZ:

C1J03_06785 C1J03_24860

SULI:

C1J05_17375

RID:	RIdsm_04325(antA_2) RIdsm_04442(antA_3)

ROM:	EI983_04510 EI983_11235 EI983_11745

ROH:	FIU89_04735(hcaE) FIU89_14340(antA4)

RPEL:

THAA:

PSEW:

SEDI:

PPSO:

PAED:

CACT:

HDH:	G5B40_19265

AMYL:

QBD29_15465

HTQ:	FRZ44_08600(yeaW) FRZ44_35700(yeaW) FRZ44_43610 FRZ44_47310(yeaW) FRZ44_48050

HADH:

FRZ61_34840 FRZ61_41530(yeaW) FRZ61_43790 FRZ61_45160 FRZ61_45770

APC:	HIMB59_00013350

BCY:	Bcer98_0763

BFD:	NCTC4823_03637(cbdA_2) NCTC4823_03640(cbdA_3)

BBAD:

K7T73_16350 K7T73_16395

BACO:

OXB_3176

BKW:	BkAM31D_21665(bedC1)

BON:	A361_03025 A361_14510

CFIR:

CSOA:

CPSS:

LAGR:

HSHI:

VNE:	CFK40_04990

PBUT:

DTO10_01915 DTO10_16030

PFRI:

L8956_15640

NMK:	CHR53_02140 CHR53_02265

NDT:	L1999_01780

NCM:	QNK12_01530 QNK12_19820 QNK12_25125

MSEM:

GMB29_06775 GMB29_10200

BAGR:

BA6348_08160

BCOP:

JD108_07945

ANX:	ACH33_04680

ATHE:

ACYC:

SPOP:

SPAE:

STUB:

ACIT:

HPK19_11355 HPK19_13185

NCX:	Nocox_19550(antA1)

NFS:	OIE67_22680

MHAI:

OHB01_24830

ASIC:

Q0Z83_055290(yeaW)

UAM:	UABAM_02282

» show all

Reference

PMID:24591617

Authors

Zhu Y, Jameson E, Crosatti M, Schafer H, Rajakumar K, Bugg TD, Chen Y

Title

Carnitine metabolism to trimethylamine by an unusual Rieske-type oxygenase from human microbiota.

Journal

Proc Natl Acad Sci U S A 111:4268-73 (2014)
DOI:10.1073/pnas.1316569111

Sequence

[acb:A1S_0852]

Reference

PMID:25440057

Authors

Koeth RA, Levison BS, Culley MK, Buffa JA, Wang Z, Gregory JC, Org E, Wu Y, Li L, Smith JD, Tang WH, DiDonato JA, Lusis AJ, Hazen SL

Title

gamma-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO.

Journal

Cell Metab 20:799-812 (2014)
DOI:10.1016/j.cmet.2014.10.006

Sequence

[eco:b1802]

All links

Ontology (3)   
   KEGG BRITE (2)   
   COG (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (2846)   
   KEGG GENES (359)   
   KEGG MGENES (2114)   
   RefGene (371)   
   OC (2)   
Literature (2)   
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