KEGG ORTHOLOGY: K23755

ORTHOLOGY: K23755

Entry

K23755                      KO

Symbol

SCO2

Name

protein SCO2

Pathway

map05230

Central carbon metabolism in cancer

Disease

H01200

Fatal infantile cardioencephalomyopathy

H01368

Cytochrome c oxidase (COX) deficiency

H02041

Myopia

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    K23755  SCO2; protein SCO2
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis
    K23755  SCO2; protein SCO2
Mitochondrial biogenesis [BR:ko03029]
Mitochondrial quality control factors
  Mitochondrial respiratory chain complex assembly factors
   Complex-IV assembly factors
    K23755  SCO2; protein SCO2

Genes

HSA:	9997(SCO2)

PTR:	100613133(SCO2)

PPS:

PON:

NLE:

HMH:

MCF:

MTHB:

CSAB:

103223567(SCO2)

CATY:

MLEU:

RRO:

RBB:

TFN:

PTEH:

CANG:

CJC:	100402785(SCO2)

SBQ:

CIMI:

CSYR:

MMUR:

LCAT:

PCOQ:

OGA:

MMU:	100126824(Sco2)

MCAL:

MPAH:

MCOC:

ANU:

MUN:

CGE:

MAUA:

PROB:

PLEU:

MORG:

MFOT:

AAMP:

NGI:

HGL:

CPOC:

CCAN:

DORD:

DSP:

PLOP:

NCAR:

MMMA:

OPI:

TUP:

GVR:

CFA:

CLUD:

VVP:

VLG:

NPO:

AML:

UMR:

UAH:

UAR:

ELK:

LLV:

MPUF:

MNP:

MLK:

NVS:

ORO:

EJU:

ZCA:

MLX:

NSU:

LWW:

FCA:	101085223(SCO2)

PYU:

PCOO:

PBG:

PVIV:

LRUF:

PTG:

PPAD:

PUC:

AJU:

HHV:

BTA:	100125923(SCO2)

BOM:

BBUB:

BBIS:

CHX:

OAS:

BTAX:

ODA:

CCAD:

MBEZ:

SSC:	100516804(SCO2)

CFR:

CBAI:

CDK:

VPC:

BACU:

BMUS:

LVE:

OOR:

DLE:

PCAD:

PSIU:

NASI:

ECB:

EPZ:

EAI:

MYB:

MYD:

MMYO:

MLF:

PKL:

EFUS:

MNA:

DRO:

SHON:

AJM:

PDIC:

PHAS:

MMF:	118641196 118641198

PPAM:

HAI:

RFQ:

PALE:

PGIG:

PVP:

RAY:

MJV:

TOD:

SARA:

LAV:

TMU:

ETF:

DNM:

GAS:

SHR:

AFZ:

PCW:

OAA:

GGA:	429671(SCO2)

PCOC:

MGP:

CJO:

TPAI:

LMUT:

NMEL:

CATA:

AFUL:

TGU:

LSR:

PMOA:

OTC:

PRUF:

OMA:

PHI:

SVG:

MMEA:

ACHC:

HLE:

AGEN:

SHAB:

DPUB:

RTD:

CUCA:

AROW:

DNE:

ASN:

AMJ:

CPOO:

GGN:

PSS:

CMY:

CCAY:

DCC:

CPIC:

TST:

CABI:

MRV:

ASAO:

PVT:

SUND:

PBI:

PMUR:

CTIG:

TSR:

PGUT:

APRI:

PTEX:

NSS:

VKO:

PMUA:

PRAF:

ZVI:	118083839 118091033

HCG:

128326277

GJA:	107112968 107125233

STOW:

125434936

EMC:

129336237

XLA:	100137652(sco2.S)

XTR:	100497895(sco2)

NPR:

RTEM:

BBUF:

BGAR:

MUO:

GSH:

DRE:	606683(sco2)

SRX:	107725531 107732966

SANH:

107695865

SGH:	107553876 107591243

CAUA:

CGIB:

PTET:

LROH:

OMC:

PPRM:

RKG:

MAMB:

CIDE:

MASI:

TROS:

TDW:

MANU:

IPU:	108274471 128634963

IFU:

PHYP:

SMEO:

TFD:

TVC:

AMEX:

CMAO:

EEE:

CHAR:

TRU:

TFS:

TNG:	GSTEN00011566G001

LCO:

NCC:

TBEN:

CGOB:

EMAC:

ELY:

EFO:

PLEP:

SLUC:

PFLV:

GAT:

PPUG:

AFB:

CLUM:

MSAM:

SCHU:

CUD:

ALAT:

MZE:

ONL:

OAU:

OLA:

OML:

CSAI:

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:

PPRL:

CVG:

CTUL:

GMU:

NFU:

KMR:

ALIM:

AOCE:

MCEP:

CSEM:

POV:

SSEN:

HHIP:

HSP:

SMAU:

LCF:

SDU:

SLAL:

XGL:

SSCV:

SBIA:

PEE:

PTAO:

BPEC:

MALB:

BSPL:

SJO:

SASA:

STRU:

OTW:	112214274 112216918

OMY:	110490334 110500155

OGO:	123994580 124014307

ONE:	115107005 115133108

OKI:	109879972 109910364

OKE:	118366270 118392387

SALP:

111949963 112080590

SNH:	120032144 120050045

CCLU:

ELS:

SFM:

PKI:

AANG:

LOC:

PSPA:

ARUT:

PSEX:

LCM:

CMK:

RTP:

CPLA:

HOC:

LERI:

PMRN:

LRJ:

CIN:

SCLV:

TUT:

DPOL:

LAK:	106152750 106162835 106168387

BEQ:	BEWA_019500

BBO:	BBOV_III004250

ZAL:	AZF00_11370

SVA:

SVA_0243

OUR:	CEQ07_02205

TRB:	HB776_30165

MEA:	Mex_1p4317

MDI:

METDI4927

MCH:

Mchl_4303

MZA:	B2G69_01570

METD:

LAGG:

PSTG:

MALG:

PABY:

RID:	RIdsm_05705

RMB:	K529_022650

MON:	G8E03_16705

ALI:	AZOLI_0647

ATI:	AL072_00625

AHU:	A6A40_02755

AZM:	DM194_02425

AZZ:	DEW08_11415

RCE:

THAL:

THAC:

MSTO:

PBRO:

Reference

PMID:10545952

Authors

Papadopoulou LC, Sue CM, Davidson MM, Tanji K, Nishino I, Sadlock JE, Krishna S, Walker W, Selby J, Glerum DM, Coster RV, Lyon G, Scalais E, Lebel R, Kaplan P, Shanske S, De Vivo DC, Bonilla E, Hirano M, DiMauro S, Schon EA

Title

Fatal infantile cardioencephalomyopathy with COX deficiency and mutations in SCO2, a COX assembly gene.

Journal

Nat Genet 23:333-7 (1999)
DOI:10.1038/15513

Sequence

[hsa:9997]

All links

Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (3)   
   KEGG DISEASE (3)   
Gene (411)   
   KEGG GENES (378)   
   KEGG MGENES (33)   
All databases (418)   

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