KEGG   Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1: VK055_4499
Entry
VK055_4499        CDS       T03418                                 
Symbol
leuA2
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
kpt  Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1
Pathway
kpt00290  Valine, leucine and isoleucine biosynthesis
kpt00620  Pyruvate metabolism
kpt01100  Metabolic pathways
kpt01110  Biosynthesis of secondary metabolites
kpt01210  2-Oxocarboxylic acid metabolism
kpt01230  Biosynthesis of amino acids
Module
kpt_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:kpt00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    VK055_4499 (leuA2)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    VK055_4499 (leuA2)
Enzymes [BR:kpt01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     VK055_4499 (leuA2)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: AIK83038
UniProt: A0A2W0K362
Position
complement(4603435..4605111)
AA seq 558 aa
MLSHPAEKYRPYPPIALPDRRWPDRQISHAPRWLSTDLRDGNQALAEPMDSARKLQFWDL
LLECGFKEIEVAFPSASQTDFNFVRQLIDEQRIPEDVTIQVLTQARDPLILRTFEALRGA
RRATVHLYNATAPLFRELVFGMDKAEVIALATRATRLIRQQCEQQPETRWQYEYSPETFC
FTEPEFALEICEAVADVWQPCAERPMIVNLPATVEVNTPNVYADQIEYFCRHFSRRGEVC
ISVHPHNDRGTGVASAELAVMAGADRVEGCLFGNGERTGNVCLVTLAMNLYSQGIDPELR
FEQMNRVVEVVENCNQIPVHPRHPWAGSLAYTAFSGSHQDAIKKGFDARQPGDPWQMPYL
PIDPQDIGCSYEAVIRVNSQSGKSGSAWLIEQNHGLKLPRGLQQDFSQHVQQATDSDGKE
MTHHALWQLFRTRYGLQAQPALTLLDYQSASQQDGQLSLQATLRHHGETRRLQGQGNGLL
SAAASGLSALFRQPFMIKDYHEHTLGARSDSRSVAYIRCVFPQGESYWGVGIDNDVARAS
LQALCNALSAADQAGGRK
NT seq 1677 nt   +upstreamnt  +downstreamnt
atgctgagccatcctgctgaaaagtaccgtccctatccgccgatcgccctgcctgaccgc
cgctggccagaccggcaaatcagtcacgccccgcgctggctgtcgactgacctgcgcgac
ggcaaccaggcgctggcggagcccatggacagcgcccgcaaactgcagttctgggatctg
ctgctggagtgcggctttaaagagattgaagtcgccttcccttccgcctcacaaaccgat
ttcaactttgtccgccagctgattgacgaacagcgcatcccggaggatgtcaccatccag
gtgctgacccaggcgcgagacccgctgatcctgcgcacctttgaggcgctgcgcggcgcc
cgccgggctaccgtccacctctacaatgccaccgcgccgctgttccgcgagctggttttc
ggcatggacaaggccgaggtgatcgccctcgcgacccgcgccacccggcttatccgtcag
cagtgcgaacagcagccggagacccgctggcaatatgaatattcgcctgaaaccttctgc
ttcaccgagcccgagtttgcgcttgagatttgcgaagcggtggcggatgtctggcagccc
tgcgccgagcgaccgatgatcgtcaatctgccggcgacggtggaagtcaacacccccaac
gtctatgccgatcagatcgagtatttttgccgccacttctcccgccgcggcgaggtctgc
atcagcgtgcacccgcataacgatcgcggcaccggcgtcgccagcgccgagctggcggtg
atggccggcgccgatcgggtagaaggctgcctgtttggcaacggcgaacgcaccggcaac
gtctgtctggtgactttggcgatgaacctctacagccagggcatcgaccctgagcttcgc
ttcgagcagatgaaccgggtggtggaggtggtggaaaactgcaaccagatccccgttcac
ccgcgccacccgtgggcgggaagtctggcttacaccgccttctccggctcccatcaggat
gcgatcaaaaaagggtttgatgcccgtcagcctggcgatccgtggcagatgccctacctg
cccattgacccgcaggatattggctgcagctatgaggcggtgatccgcgtcaacagccag
tcggggaagagcggcagcgcctggcttatcgaacaaaatcatggtctgaaactgccccgc
gggctgcagcaggacttcagccagcacgttcagcaggccaccgatagcgacggcaaagag
atgacccaccatgcgctgtggcagctgttccgcacgcgctacgggctgcaggcgcagccg
gcgctgacgctgctcgattatcagagcgccagccagcaggatggccagctttccctgcag
gcaacgctgcgtcaccacggcgaaacccgacgcctgcagggccagggcaacggcctgctc
tccgccgcagccagcgggctcagcgcgctgtttcggcagccgtttatgatcaaggactat
catgagcatacgctcggcgcgcgcagcgacagccggtcggtggcctatatccgctgcgtt
tttccgcaaggagaaagctactggggcgtgggtatcgataatgacgtggcgcgcgcctcg
ctgcaggcactgtgcaatgcgctcagcgccgccgatcaggccgggggacgaaaatag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (23)   

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