KEGG   Loxodonta africana (African savanna elephant): 100661527
Entry
100661527         CDS       T04351                                 
Symbol
HMGCS1
Name
(RefSeq) hydroxymethylglutaryl-CoA synthase, cytoplasmic isoform X2
  KO
K01641  hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav00280  Valine, leucine and isoleucine degradation
lav00650  Butanoate metabolism
lav00900  Terpenoid backbone biosynthesis
lav01100  Metabolic pathways
lav03320  PPAR signaling pathway
Module
lav_M00095  C5 isoprenoid biosynthesis, mevalonate pathway
Brite
KEGG Orthology (KO) [BR:lav00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00650 Butanoate metabolism
    100661527 (HMGCS1)
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    100661527 (HMGCS1)
  09109 Metabolism of terpenoids and polyketides
   00900 Terpenoid backbone biosynthesis
    100661527 (HMGCS1)
 09150 Organismal Systems
  09152 Endocrine system
   03320 PPAR signaling pathway
    100661527 (HMGCS1)
Enzymes [BR:lav01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.10  hydroxymethylglutaryl-CoA synthase
     100661527 (HMGCS1)
SSDB
Motif
Pfam: HMG_CoA_synt_C HMG_CoA_synt_N Cullin ACP_syn_III PS_Dcarbxylase
Other DBs
NCBI-GeneID: 100661527
NCBI-ProteinID: XP_003408063
UniProt: G3TJX8
Position
Unknown
AA seq 520 aa
MPGSLPLNAEACWPKDVGIVALEIYFPSQYVDQAELEKYDGVDAGKYTIGLGQAKMGFCT
DREDINSLCLTVVQNLMARNNLSYDCIGRLEVGTETIIDKSKSVKTNLMQLFEESGNTDI
EGIDTTNACYGGTAAVFNAVNWIESSSWDGRYALVVTGDIAVYATGNARPTGGAGAVALL
IGPNAPLIFERGLRGTHMQHAYDFYKPDMLSEYPIVDGKLSIQCYLSALDRCYSVYRKKI
RAQWQKEGNDRDFTLNDFGFVIFHSPYCKLVQKSLARMLLNDFLNDQNRDKNSIYSGLEA
FGDVKLEDTYFDRDVEKAFMKASSELFNQKTKASLLVSNQNGNMYTSSVYGSLASVLTQY
SPQQLAGKRIGVFSYGSGLAATLYSLRVTQDATPGSALDKITASLCDLKSRLDSRTCVAP
DVFAENMKLREDTHHLVNYIPQGSIDSLFEGTWYLVRVDEMHRRTYARRPSLNDDSLEEG
VGLVHSNKATEHIPSPAKKVPRLPATAAEPEAAVISNGEH
NT seq 1563 nt   +upstreamnt  +downstreamnt
atgcctgggtcacttcctttgaatgcggaagcctgctggccaaaagatgtgggaattgtt
gcccttgagatctattttccttctcaatatgttgatcaagcagagttagaaaaatatgat
ggtgtagatgctgggaagtataccattggcttgggccaggccaagatgggcttctgcaca
gacagagaagacatcaactctctttgcttaactgtggttcagaatcttatggccagaaat
aacctgtcctatgattgcattggacgattggaagttggaacagagacaatcatcgacaaa
tcaaagtcagtgaagacgaatttgatgcagctatttgaggagtctgggaacacagatata
gaaggaatagatacaactaatgcatgctatggaggcacagctgctgtctttaatgctgtt
aactggatcgagtccagctcctgggatggacggtacgccctggtggttactggagatatt
gctgtgtatgcgacggggaatgccagaccaacaggaggagctggagctgttgctctgcta
attggcccaaatgctcctttaatttttgagcgagggcttcgtgggacccatatgcagcat
gcctatgacttctataagcctgatatgctctctgagtatcctatagtggatggaaaactc
tccatacagtgctacctcagtgcattagaccgctgctattctgtctatcgcaaaaagatc
cgtgcccagtggcagaaggagggaaatgatagagatttcactttgaatgacttcggcttt
gtcatctttcactcaccgtattgtaaactggttcagaaatctctagctcggatgttgctg
aatgactttcttaatgaccaaaacagagataaaaatagtatctatagtggcctggaagcc
tttggggatgttaaattagaagatacctactttgatagagatgtggaaaaggcatttatg
aaggctagttctgaactctttaatcagaaaacaaaggcatctttgcttgtgtcaaatcaa
aatggaaatatgtacacatcttcagtatatggttcccttgcttctgttctaacacagtat
tcccctcagcagctggcaggaaagaggattggtgtcttctcttacggttctggtttggct
gccaccttgtactcccttagagttacacaagatgctacacctgggtctgctctagataaa
ataacagcaagtttatgtgacctcaaatcaaggcttgactcaagaacttgtgtggcacca
gatgtctttgctgaaaatatgaagctcagagaggacactcaccacttggtcaactatatt
ccccagggttcaattgattcactttttgaaggaacatggtacttggttagagtggatgaa
atgcaccgaagaacttacgctcggcgcccatctctgaatgatgactctttggaggaagga
gtaggacttgtacattcaaacaaagcaactgagcatattccaagtcctgctaagaaagtg
ccaagactccctgcaacagcagcagaaccagaagcagctgtcattagtaacggggagcat
taa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (5)   
   KEGG MODULE (3)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (5)   
   Pfam (5)   
All databases (40)   

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