KEGG   Loxodonta africana (African savanna elephant): 100663651
Entry
100663651         CDS       T04351                                 
Symbol
SYK
Name
(RefSeq) LOW QUALITY PROTEIN: tyrosine-protein kinase SYK
  KO
K05855  spleen tyrosine kinase [EC:2.7.10.2]
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav04064  NF-kappa B signaling pathway
lav04072  Phospholipase D signaling pathway
lav04151  PI3K-Akt signaling pathway
lav04380  Osteoclast differentiation
lav04611  Platelet activation
lav04613  Neutrophil extracellular trap formation
lav04625  C-type lectin receptor signaling pathway
lav04650  Natural killer cell mediated cytotoxicity
lav04662  B cell receptor signaling pathway
lav04664  Fc epsilon RI signaling pathway
lav04666  Fc gamma R-mediated phagocytosis
lav05152  Tuberculosis
lav05167  Kaposi sarcoma-associated herpesvirus infection
lav05168  Herpes simplex virus 1 infection
lav05169  Epstein-Barr virus infection
lav05171  Coronavirus disease - COVID-19
lav05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:lav00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    100663651 (SYK)
   04072 Phospholipase D signaling pathway
    100663651 (SYK)
   04151 PI3K-Akt signaling pathway
    100663651 (SYK)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100663651 (SYK)
   04613 Neutrophil extracellular trap formation
    100663651 (SYK)
   04625 C-type lectin receptor signaling pathway
    100663651 (SYK)
   04650 Natural killer cell mediated cytotoxicity
    100663651 (SYK)
   04662 B cell receptor signaling pathway
    100663651 (SYK)
   04664 Fc epsilon RI signaling pathway
    100663651 (SYK)
   04666 Fc gamma R-mediated phagocytosis
    100663651 (SYK)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100663651 (SYK)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    100663651 (SYK)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    100663651 (SYK)
   05168 Herpes simplex virus 1 infection
    100663651 (SYK)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100663651 (SYK)
   05169 Epstein-Barr virus infection
    100663651 (SYK)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    100663651 (SYK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:lav01001]
    100663651 (SYK)
Enzymes [BR:lav01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     100663651 (SYK)
Protein kinases [BR:lav01001]
 Non-receptor tyrosine kinases
  SYK family
   100663651 (SYK)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 Kdo ABC1 RIO1
Other DBs
NCBI-GeneID: 100663651
NCBI-ProteinID: XP_010598272
Position
Unknown
AA seq 634 aa
MASGAADSANNLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAYGRKA
HHYTIERELNGTYAISGGRAHASPAELCLYHTQESDGLVCLLKKSFNRPAGVQPRXGPFE
DLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISRDESEQI
VLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLV
EHYSYKADGLLRVLTVPCQKIGTDNGNINFGARPPLPSSHSVTWSAGGIISRIKSYSFPK
PGHRKAPSSQGSRPESSVFNPYEPDRGPWATERGPQREALPMDTEVYESPYADPEEIRPK
EVYLDRSLLTLEDNELGSGNFGTVKKGYYKMKKVVKTVAVKILKNEANDPALKDELLAEA
NVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMG
MKYLEECNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAP
ECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVSVMLEKGERMGCPPGCPREM
YELMTLCWTYEVENRPGFAAVELRLRNYYYDVVN
NT seq 1905 nt   +upstreamnt  +downstreamnt
atggccagtggcgcagccgacagtgccaacaacctgcccttcttttttggcaacatcacc
cgagaggaagcagaagattacctggtgcagggaggcatgagcgacgggctctacctgctg
cgccaaagccgcaattacctgggagggtttgccctgtccgtggcctatgggaggaaggca
caccactacaccattgagcgtgagctgaacgggacctacgccatctcaggtggcagggcc
catgccagccccgctgaactctgcctctaccacacccaggagtctgacggccttgtctgc
ctcctcaagaagtctttcaaccgacccgctggggtgcagcccagangcggaccctttgaa
gacttgaaggaaaaccttattagggagtatgtgaaacagacctggaatctgcagggtcaa
gctttggagcaagccatcatcagtcagaagccacagctggagaagctcattgccaccact
gcccatgaaaaaatgccctggttccatggaaaaatcagccgggatgagtctgagcagatt
gtcctaataggatcaaagacaaacggaaaatttttgattcgtgcccgagacaacaatggg
tcctatgccctctgtctgctgcatgaggggaaggtgctacactatcgcatcgataaagac
aaaaccgggaaactgtccatccccgaaggaaagaagttcgacacactttggcagctagtg
gagcattattcttataaagcagatggtttgttacgagttcttacggttccctgtcaaaaa
attggcacagacaatggaaatattaatttcggggctcggccaccacttccaagttcccat
tctgtgacttggtcagcgggtggaataatctcaagaatcaaatcatactccttcccaaag
cctggccacagaaaggcaccctcatcccaaggtagccggccagaaagttccgtgttcaat
ccttatgagccagaccgaggaccttgggccactgaacgaggtccccagagagaagccttg
cccatggacaccgaagtgtacgaaagcccctacgcagaccccgaagagatcaggccaaaa
gaggtctatctggaccgaagtctgctgactctggaagacaatgagcttggctctgggaac
tttggcactgtgaaaaagggttactacaaaatgaaaaaagtcgtaaaaacagtggccgtg
aaaatactgaagaacgaagccaacgaccccgctctgaaggacgagctgctggcggaagcc
aacgtcatgcagcagctggacaacccttacatcgtgcgcatgatcgggatctgcgaggcc
gagtcctggatgctggtgatggagatggcggagctcgggcctctcaataagtacctgcag
cagaacaggcatgtcaaggataagaacataatagagctggttcatcaggtttctatggga
atgaagtatttggaggagtgcaattttgtgcaccgagatctggctgcaagaaacgtgttg
ctggttactcaacattatgccaaaatcagtgactttggactttccaaagcacttcgtgct
gatgaaaactactacaaggcccagactcacgggaagtggcctgtgaagtggtacgctcct
gaatgcatcaactactacaagttctccagcaaaagtgatgtctggagcttcggcgtgctg
atgtgggaagccttttcctatggacagaagccttatcggggaatgaaaggaagtgaagtg
tctgttatgctagagaagggagaaaggatggggtgccctccaggctgtccaagagagatg
tacgagctgatgaccctgtgctggacatacgaggtggagaacaggcctggatttgcagca
gtggagctgcggctgcggaattactactacgatgtggttaactaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (17)   
   KEGG PATHWAY (17)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (9)   
   RefSeq(pep) (9)   
DNA sequence (9)   
   RefSeq(nuc) (9)   
Protein domain (6)   
   Pfam (6)   
All databases (53)   

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