KEGG   Leishmania mexicana: LMXM_28_2280
Entry
LMXM_28_2280      CDS       T02288                                 
Name
(RefSeq) DNA topoisomerase ii
  KO
K03164  DNA topoisomerase II [EC:5.6.2.2]
Organism
lmi  Leishmania mexicana
Brite
KEGG Orthology (KO) [BR:lmi00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:lmi03032]
    LMXM_28_2280
   03036 Chromosome and associated proteins [BR:lmi03036]
    LMXM_28_2280
Enzymes [BR:lmi01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.2  DNA topoisomerase (ATP-hydrolysing)
     LMXM_28_2280
DNA replication proteins [BR:lmi03032]
 Eukaryotic type
  DNA Topoisomerases
   LMXM_28_2280
Chromosome and associated proteins [BR:lmi03036]
 Eukaryotic type
  Chromosome condensation proteins
   Other regulators of chromosome condensation
    LMXM_28_2280
  Centrosome formation proteins
   Centriole proteins
    LMXM_28_2280
SSDB
Motif
Pfam: DNA_topoisoIV TOPRIM_C DNA_gyraseB HATPase_c Toprim DNA_gyraseB_C
Other DBs
NCBI-GeneID: 13450353
NCBI-ProteinID: XP_003877071
UniProt: E9B049
Position
28:874138..878631
AA seq 1497 aa
MGKTVEQIYQKKTQHDHILTRPDMYIGTIEPVTDDIWVYDDAENIMKQHKCTWTPGLYKI
FDEILVNAADNKVRDPIGQTVIRVWMTENYVRVYNNGEGIPIQKHREHDLWVPEMIFGHL
LTSSNYDDEEAKVTGGRNGFGAKLTNVFSKQFEVETVHSRSRKKFYMKWTNNMLQHDDPI
IVSCDSADYTMVTFYPDFARFHVDKFSEDMLLMMKRRVYDVAGCTDKTLKCFLNDERIAC
TTFPEYVDLYPTMGEERKAASYSRVNDRWEVCVRVSNIGPQQVSFVNSIATTRGGTHVKY
IMDQIISKVVEQAKKKKKTDVKPHMIRPHIFLFVNCLIENPGFDSQTKETLNTVKSKFGS
TCDLPNSIIDYIMSSGIVERSVEMANSKIAKEMASKMRSSDRKQIMGIPKLDDANEAGGK
YSHRCTLILTEGDSAKTLCTAGLAVKDRDYFGVFPLRGKPLNVREASLKKLAACEEIQCV
MKIMGLDIRQKYENTDGLRYGHLMIMSDQDHDGSHIKGLLINFIHCFWPSLLRVPGFLQE
FITPIVKARPKGRGGAGKAISFFSMPDYFEWKKAIGDNLSNYQIRYYKGLGTSGAEEGRE
YFENIDRHRLSFVEQEQSEEDRIVMAFGKDRVEDRKEWITNFKTNVNVNESMDYNVRQVS
YRDFVDKELILFSIADCERSIPSVIDGFKPGQRKILFSCFKRNLVNSIKVVQLAGYVSEH
SAYHHGEQSLVQTIVGMAQDFVGSNNVPLLRKDGQFGTRLHGGKDHAAGRYIFTRLMQVA
RAIFHPADDFVVEYKDDDGLSVEPFFYIPVIPMVLVNGTTGIGTGFSTSIPNYNPLEIIS
NLERLMQGEEVHKMQPWYFGFTGTMEEKEPGKFVSHGRYEIRPDGVVCITELPIGVWTQT
YKKFLEDMREKELVVQYREHTTDVTVDFEVFLHPQVLEQWVAQDVVEERLQLKEYVHATN
IIAFNKEGQITKYSDAESVLKEFYLVRLDYYAKRKQYLLGELRRLTSKLENMVRFVREVV
EGTLVVTKRKKKELLEDLQRRMYLPFPPHTKKKLSSTTVEEGDGEAAPDTQNSEDDVLGM
GRAADGEADDGAAEPPEVRRATRDYDYLLGMKLWSLTAEMIARLEAQMAKARRDTATMEA
RTPKETWMEDLKVLRTRLESFYADREVEIATIQRKKVKKPFDTRRLRVPILSDKARSLLQ
KEAVKAIKANGAGGRRRVGGGDDALVGGAASAVGEAARPKPKKPVAKKRRKAKNSDDDDD
SNSDEEWMFDDSDDDDEGENIMGMGDAGAPPVPESARPRGSPKKPRAAPKRRAGSKPRKK
VRNSDDDDSSDSSISGSSKPVRRRPKKDATLSATAAATKTAVDDLDLDGFGLDALTSASP
ASAAPKMAMAAASLSNGAAARSTKPTADADDDLLLLGLSKAKPQTAPQTAPAASKRTAAT
STRPAKPHAKPPAQRRRRRSSSDASDDDGEDSTDASASSSEESFASSDSDSDYSFSD
NT seq 4494 nt   +upstreamnt  +downstreamnt
atgggcaaaaccgtagaacagatttaccagaagaagactcagcatgatcacatcctcacg
cgtcctgacatgtacatcggcacgattgagccggtgacagacgacatctgggtctatgac
gatgcagagaacattatgaagcagcacaagtgcacctggacacccgggctgtacaagatc
tttgatgagatactggtcaatgcggcggacaacaaggtacgcgacccgatcggccagacc
gtcattcgggtgtggatgacggagaactatgtgcgagtgtacaacaacggcgagggcatc
ccaatccagaagcatcgcgagcacgatctctgggtgccggaaatgatctttgggcacctc
ctcacctcctccaactatgacgatgaggaggcgaaggtgacgggcgggcgcaacggcttc
ggcgcgaagctgacgaacgtattctcgaagcagttcgaggtcgagaccgtgcacagccgc
tctcgcaagaagttctacatgaaatggacgaacaacatgctgcaacacgacgaccctatt
atcgtgtcgtgcgacagcgccgactacaccatggtcaccttttaccccgactttgcacgc
ttccacgtcgataagtttagcgaggacatgctgctgatgatgaagcgacgcgtgtacgac
gtcgcggggtgcaccgacaagacactcaagtgcttcctgaacgatgagcgcatcgcctgc
accactttcccggagtacgtcgacctctaccccaccatgggcgaggagaggaaggcggcg
agctactcgcgcgtgaatgaccggtgggaggtgtgcgtacgtgtgtcgaacattgggcca
cagcaggtgagcttcgtcaactccatcgccaccacccgcggcggcacacatgtcaagtac
atcatggaccaaatcatctccaaggtggtggagcaggccaagaaaaagaagaagacagac
gtgaagccgcacatgattaggccgcacatttttttattcgtcaactgcctcatcgagaac
cccggcttcgactcgcagacgaaggagaccctcaacactgtcaagagcaagttcggcagc
acgtgcgacctgcccaacagcatcatcgactacatcatgagctccggcatcgttgagcgc
tcagtcgagatggcgaacagcaagatcgcgaaggagatggcgtccaagatgaggtcgtcg
gaccggaaacagatcatgggcatcccgaagctggacgacgccaacgaggcgggcggcaag
tacagccaccgctgcacgctcatcctcacagagggtgactcagccaagacactctgcacg
gccggcctggcggtgaaggaccgggactactttggcgtgtttccgctgcgcggcaaaccc
ctcaacgtgcgcgaggcgtcgctgaagaagctggcggcctgcgaggagatccagtgcgtc
atgaagattatggggctcgacattcgccaaaagtacgagaacacagacgggctgcgctac
ggccaccttatgatcatgtccgatcaggaccatgacgggtcgcacatcaaagggctgctc
atcaacttcattcactgcttctggccgagcctgctgcgggtgcctggctttcttcaggag
ttcatcacgccgattgtgaaagcccggccaaaaggccgcggcggggccggcaaggccatc
tccttcttctccatgccggactacttcgagtggaagaaggcgattggtgacaacctgagc
aactaccaaattcggtactacaagggtctcggcacgtccggcgctgaggagggccgcgag
tacttcgagaacattgaccggcaccgcctcagctttgtggagcaggagcagagcgaggag
gaccgcattgtcatggcctttggcaaggaccgcgtcgaggaccgcaaggagtggatcacg
aacttcaagacgaacgtgaacgtgaatgagtcgatggactacaacgtgcgccaggtgtcg
tatcgagactttgtggacaaggagctgattctcttctccatcgccgactgcgagcgcagc
atcccgagcgtgattgacggcttcaagcccggccagcgcaagatcctgttctcctgcttc
aagcgcaacttggtgaactccatcaaggtcgtgcagcttgccggctacgtctcggagcac
tccgcctaccaccacggcgagcagtcgcttgtccagacgatcgtcggaatggcgcaggac
tttgtgggcagcaacaacgttccgctgctccgcaaggatggccagttcggtacgcgtctg
cacggtggcaaggaccacgccgcgggccgctacatcttcacccggctcatgcaggtcgcc
cgggccatctttcacccggccgacgactttgtggtcgagtacaaggacgacgacggtctc
tcggtggagcctttcttctacattccggtcatcccaatggtgctggtgaacggcacgacg
ggcatcggcaccgggttcagcacgagcatcccgaactacaacccgctggagatcatcagc
aacctcgagcgcctcatgcagggcgaggaggtgcacaagatgcagccgtggtacttcggc
ttcaccggcacaatggaggagaaggagccaggtaagttcgtctcccacggtaggtacgag
atacgcccggatggggtggtgtgcatcacggagctgccgatcggggtgtggacgcagacg
tacaagaagttcctggaggacatgcgggagaaggagctcgtggtgcagtaccgcgagcac
acgacggatgtgacagtggacttcgaagtgtttctgcatccccaggtgctggagcagtgg
gtcgcgcaggatgtcgtggaggagcggctgcagctgaaggagtacgtgcacgcgacgaac
atcatcgccttcaacaaggagggccagatcaccaagtactcggacgcggagtcggtgctc
aaggagttctacctcgtacgcctcgactactacgcgaagcgcaagcagtacctcttgggt
gagctgcgtcggctgacgagcaagttggagaacatggtccgctttgtgcgtgaggtggtg
gagggcacgcttgttgtgaccaagcggaaaaagaaagagctgctcgaggacctgcagcgg
cgcatgtatctgcccttcccgccccacacaaagaaaaagctgtcttcgacaaccgtggag
gagggggacggcgaggcggcgcccgacacgcagaacagcgaggatgacgtgctgggcatg
ggacgcgccgccgacggtgaagcagacgacggcgcggcagaaccgccggaggtgcgtcgt
gccactcgcgactacgactacctgcttggcatgaagctgtggagcctcacggcggagatg
attgcgcggctggaggcgcagatggccaaggcccgccgcgacactgccacgatggaggcc
cgcacaccgaaagaaacgtggatggaggacctcaaggtgctgcgcaccaggctggagagc
ttctacgcggaccgcgaagtggagattgccaccattcaacgcaagaaggtgaagaagccg
tttgacactcgacgactgcgcgtgccgatcttatctgacaaggcgcgctctctgctgcag
aaggaggcggtgaaggccataaaggcaaacggcgccggcggccgccgtcgcgtcggcggt
ggcgatgacgcgcttgtcggtggagccgcctcggccgttggtgaggccgcgcggccgaag
ccgaagaagcccgtggcgaagaagcgacgcaaggcaaagaacagcgatgacgacgacgac
agcaactccgatgaggagtggatgtttgacgacagcgatgatgacgatgagggcgagaac
atcatgggtatgggtgatgccggagcgccgccggtgccggagagcgcacggccgcgcggc
tctccgaagaagccccgcgcagctccgaagcgccgcgcgggatcgaagccgcgcaagaag
gtccgtaacagcgacgacgacgactcaagcgacagcagcatcagcggaagctccaagcca
gtgaggcgcaggcccaagaaggacgcgacattgtcagccactgctgctgctacgaagact
gcggttgatgaccttgacctggacggctttggactcgatgcgctcacctctgcttcaccg
gcgagtgccgctccgaagatggccatggctgccgcgtccctgtcaaacggtgctgcagcg
cgctccacaaagcccaccgcagacgccgacgatgatctcctcctgctggggctcagcaag
gcgaagccacagacagctccacagactgccccagcagccagcaagaggaccgctgccacc
tctacccgccctgcaaagccgcacgcgaagccgcctgctcagcggcgacgccgccgcagc
agcagtgacgcgagcgatgatgatggcgaagacagcaccgatgcgtcggcgtcgtcatcg
gaggaatccttcgcgtcatccgactccgactctgactacagcttcagtgactag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (6)   
   Pfam (6)   
All databases (19)   

Download RDF
DBGET integrated database retrieval system