KEGG   Lipotes vexillifer (Yangtze River dolphin): 3802089
Entry
3802089           CDS       T03090                                 
Symbol
ND4, KEG26_p04
Name
(RefSeq) NADH dehydrogenase subunit 4
  KO
K03881  NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]
Organism
lve  Lipotes vexillifer (Yangtze River dolphin)
Pathway
lve00190  Oxidative phosphorylation
lve01100  Metabolic pathways
lve04714  Thermogenesis
lve04723  Retrograde endocannabinoid signaling
lve05010  Alzheimer disease
lve05012  Parkinson disease
lve05014  Amyotrophic lateral sclerosis
lve05016  Huntington disease
lve05020  Prion disease
lve05022  Pathways of neurodegeneration - multiple diseases
lve05208  Chemical carcinogenesis - reactive oxygen species
lve05415  Diabetic cardiomyopathy
Module
lve_M00142  NADH:ubiquinone oxidoreductase, mitochondria
Brite
KEGG Orthology (KO) [BR:lve00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    3802089 (ND4)
 09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    3802089 (ND4)
  09159 Environmental adaptation
   04714 Thermogenesis
    3802089 (ND4)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    3802089 (ND4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    3802089 (ND4)
   05012 Parkinson disease
    3802089 (ND4)
   05014 Amyotrophic lateral sclerosis
    3802089 (ND4)
   05016 Huntington disease
    3802089 (ND4)
   05020 Prion disease
    3802089 (ND4)
   05022 Pathways of neurodegeneration - multiple diseases
    3802089 (ND4)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    3802089 (ND4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis [BR:lve03029]
    3802089 (ND4)
Enzymes [BR:lve01000]
 7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.2  NADH:ubiquinone reductase (H+-translocating)
     3802089 (ND4)
Mitochondrial biogenesis [BR:lve03029]
 Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial DNA-encoded proteins
   Mitochondrial respiratory chain complex I
    3802089 (ND4)
SSDB
Motif
Pfam: Proton_antipo_M Oxidored_q5_N
Other DBs
NCBI-GeneID: 3802089
NCBI-ProteinID: YP_423958
UniProt: Q2YG57
Position
MT
AA seq 459 aa
MLKFIIPTITLMPLTWLSKNKFIWINTTAHSLLISFTSLLLLNQFNDNSLNYSLMFFSDP
LSAPLLILTMWLLPLMLMASQFHLLKETPNRKKLYISMLIMLQTFLIMTFTAMELTLFYI
MFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLTGSLPLLVALMYLQNMLGSLNFLLLQ
YWTQPLSSSWSNIFMWLACMMAFLVKMPLYGLHLWLPKAHVEAPIAGSMVLAAVLLKLGG
YGMLRITSILDPLTEDMAYPFLTLSLWGMIMTSSICLRQTDLKSLIAYSSISHMALVITA
ILIQTPWSYMGATALMIAHGLSSSMLFCLANSNYERIHSRTMILARGLQIFLPLMATWWL
LACLTNLALPPTINLIGELLVITSTFSWSNSTIILLGTNTVITALYSLYMLITTQHGKYT
HHINNLYPSFTREHALMALHIIPLLLLSLNPKIIMGTPY
NT seq 1378 nt   +upstreamnt  +downstreamnt
atgctaaaatttatcatccccactattacactaataccactaacatgattatcaaaaaac
aaattcatctgaattaacactacagcccacagcctattaattagcttcacaagcctactc
ttacttaaccagttcaacgacaacagcctaaactactccctaatattcttctctgaccct
ctctcagcaccgctcttaatcctaacaatatgactcctccctctaatactaatagcaagc
caattccacctgcttaaagaaacacctaaccgaaaaaaactctatatctctatactaatt
atactacaaacttttctaattataacatttactgctatagaactaaccctattctacatt
atatttgaagccacgctaattcccaccctcattattatcacccgctgaggcaaccaaaca
gaacgactaaacgctggactatatttcttattctacacactcacaggctcccttccatta
ttagtagcactaatatatctacaaaatatattaggatccctaaactttttactattacaa
tactgaacccaacccctatcctcctcttgatcaaatatcttcatatgactagcctgtata
atagcttttctagtaaaaatacctctctacggcctacacctttgactacccaaagcacat
gtagaagcccctatcgcaggttctatagtcctagcagccgtattactaaagctaggaggc
tacggtatattacgaattacatcaattcttgaccccttaacagaagatatggcctatccc
ttcctcacactatccttatgaggaataatcataaccagctccatctgcttacgccaaacg
gacttaaaatcactcattgcatattcttcaattagccacatagcacttgtcatcacagct
atcctaatccaaaccccctgaagctacataggagctaccgccctaataattgcccacggc
ctctcatcctcaatactattctgcctagcaaactcaaactacgaacgaattcacagtcga
actataattctagcacgaggcctacaaatctttctaccactaatagcaacctgatgacta
ctagcatgcttaacaaacttagccttacctccaactattaatctaatcggagaactactt
gtaattacatcaaccttttcatgatcaaactctactattatcctattaggaacaaatact
gtaatcacagctctctactccctatatatactaatcacaacacaacacggcaaatatacc
caccacatcaataatctttacccctccttcacacgagaacacgccttaatagccctccac
atcattcccttattgctcctatctctaaaccccaaaatcatcataggaaccccctact

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (13)   
   KEGG PATHWAY (12)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   RefGene (19)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (51)   

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