KEGG   Leptonychotes weddellii (Weddell seal): 102733337
Entry
102733337         CDS       T08708                                 
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic
  KO
K00600  glycine hydroxymethyltransferase [EC:2.1.2.1]
Organism
lww  Leptonychotes weddellii (Weddell seal)
Pathway
lww00260  Glycine, serine and threonine metabolism
lww00630  Glyoxylate and dicarboxylate metabolism
lww00670  One carbon pool by folate
lww01100  Metabolic pathways
lww01200  Carbon metabolism
lww01230  Biosynthesis of amino acids
lww01240  Biosynthesis of cofactors
lww01523  Antifolate resistance
Module
lww_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:lww00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    102733337 (SHMT1)
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    102733337 (SHMT1)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    102733337 (SHMT1)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    102733337 (SHMT1)
Enzymes [BR:lww01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.1  glycine hydroxymethyltransferase
     102733337 (SHMT1)
SSDB
Motif
Pfam: SHMT DegT_DnrJ_EryC1
Other DBs
NCBI-GeneID: 102733337
NCBI-ProteinID: XP_030876778
UniProt: A0A7F8Q8X2
Position
Unknown
AA seq 483 aa
MTQANGAHKDAALWSSHDKMLLQPLKEGDTEVYNIIKKESNRQRVGLELIASENFASRAV
LEALGSCLNNKYSEGYPGQRYYGGTEFIDELEILCQKRALQVYGLDPECWGVNVQPYSGS
PANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYI
NYDQLEENARLFHPKLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGVV
PSPFEHCHVASTTTHKTLRGCRAGMIFYRRGVRSVDPKTGKETLYNLESLINSAVFPGLQ
GGPHNHAIAGVAVALKQAMTPEFRLYQRQVVANCRVLAETLMELGYKVVTGGSDNHLILV
DLRSKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKEFQKV
AQFIHRGIELTLQIQNDVGARATLKEFREKLAGDEKHQRAVGALREEVESFASLFPLPGL
PDF
NT seq 1452 nt   +upstreamnt  +downstreamnt
atgactcaagccaacggggctcacaaggatgctgccctgtggtcgtcgcatgataaaatg
ctgctacagcccctgaaagaaggtgacaccgaggtttacaacatcatcaagaaggagagt
aaccggcagagggtcgggctggagctgatcgcgtcagagaatttcgccagccgagcagtt
ttggaggccctgggctcttgcttaaataacaagtactccgaggggtacccaggccagagg
tattatggcgggaccgagttcatcgacgagctggagatcctctgtcagaagcgagcgctg
caggtctatggtctggaccccgagtgctggggggtcaatgtccagccctactcaggctcc
cccgccaacttcgcggtgtacaccgccctggtggagccccacgggcgcatcatgggcctg
gacctgcccgatggcggccacctgacccacgggttcatgacagacaagaagaaaatctct
gccacatccatcttttttgaatctatgccctataaggtgaacccggacaccggctacatc
aactatgaccaactggaggaaaatgcccgcctcttccacccgaagctgattatcgcagga
accagctgctactcccgaaacctggactacgctcgactgaggaagatcgcggacgacaac
ggggcgtatctcatggccgacatggcgcacatcagcgggctggtggcggctggcgtggtg
ccctccccctttgagcactgccacgtggcgtccaccaccacccacaaaaccctgagaggc
tgccgagctggcatgatcttctacaggagaggagtgcgcagcgtggatcccaagacgggc
aaagagactctgtacaacctggagtcgcttatcaactcggccgtgttcccaggcctgcag
ggcggtccccacaaccacgccattgctggggtcgctgtggccctgaagcaagcgatgact
ccggaattcagactttaccagcgccaggtggtggccaactgccgggttctggctgagacc
ctgatggagctgggctacaaagtggtgacaggtggttctgacaaccatttgatcctcgtg
gatctccgttccaaaggcacggacgggggaagggctgagaaggttctagaagcctgttct
attgcctgtaataagaacacctgtccaggtgacaaaagcgcactgcggcccagcggactg
cgtctggggactccagccctgacatcccgaggacttttggaaaaagagttccagaaagta
gcccagtttattcacagagggatagaactgactctgcagattcagaacgacgttggggcc
agggccaccctgaaggagttcagagagaaactggcaggggacgagaagcaccaaagggcc
gtcggggctctcagggaggaggtggagagcttcgcatctctcttccctctgcctggcctg
cctgacttctag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (13)   
   KEGG PATHWAY (8)   
   KEGG MODULE (5)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (2)   
   Pfam (2)   
All databases (36)   

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