KEGG T02451: K60

Mycobacterium tuberculosis variant bovis BCG Korea 1168P: K60_010250

Entry

K60_010250        CDS       T02451

Name

(GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase

K00602

phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]

Organism

mbk Mycobacterium tuberculosis variant bovis BCG Korea 1168P

Pathway

mbk00230

Purine metabolism

mbk00670

One carbon pool by folate

mbk01100

Metabolic pathways

mbk01110

Biosynthesis of secondary metabolites

Module

mbk_M00048

De novo purine biosynthesis, PRPP + glutamine => IMP

Brite

KEGG Orthology (KO) [BR:mbk00001]
09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    K60_010250
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    K60_010250
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mbk04147]
    K60_010250
Enzymes [BR:mbk01000]
2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     K60_010250
3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     K60_010250
Exosome [BR:mbk04147]
Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K60_010250

SSDB

Motif

Pfam:

AICARFT_IMPCHas MGS

Other DBs

NCBI-ProteinID:

AGE66935

UniProt:

A0A7U4F9F0

Position

1069015..1070586

AA seq 523 aa
MSTDDGRRPIRRALISVYDKTGLVDLAQGLSAAGVEIISTGSTAKTIADTGIPVTPVEQL
TGFPEVLDGRVKTLHPRVHAGLLADLRKSEHAAALEQLGIEAFELVVVNLYPFSQTVESG
ASVDDCVEQIDIGGPAMVRAAAKNHPSAAVVTDPLGYHGVLAALRAGGFTLAERKRLASL
AFQHIAEYDIAVASWMQQTLAPEHPVAAFPQWFGRSWRRVAMLRYGENPHQQAALYGDPT
AWPGLAQAEQLHGKDMSYNNFTDADAAWRAAFDHEQTCVAIIKHANPCGIAISSVSVADA
HRKAHECDPLSAYGGVIAANTEVSVEMAEYVSTIFTEVIVAPGYAPGALDVLARKKNIRV
LVAAEPLAGGSELRPISGGLLIQQSDQLDAHGDNPANWTLATGSPADPATLTDLVFAWRA
CRAVKSNAIVIAADGATVGVGMGQVNRVDAARLAVERGGERVRGAVAASDAFFPFPDGLE
TLAAAGVTAVVHPGGSVRDEEVTEAAAKAGVTLYLTGARHFAH

NT seq 1572 nt +upstreamnt +downstreamnt
atgagcaccgacgacggaagacggccgatccgccgtgcgctgatcagcgtgtacgacaag
accgggctggtagacctggcacagggcctgagcgcggccggcgtcgagatcatctcgact
gggtcaacggccaagaccattgccgacaccgggattccggtgacccccgtggagcagctg
accggctttcccgaggtgctcgatggccgggtcaagacactgcacccgcgagtgcatgcc
gggctgctggctgacctgcgcaagtccgagcacgccgcggccctcgagcaactcgggatc
gaggctttcgaactcgttgtagtcaacttgtatccgttcagccagaccgtcgaatccggc
gccagtgtcgacgactgcgtcgagcagattgatatcggcgggccggcgatggtgcgggcc
gccgccaaaaaccatcccagcgcggcggtggtcaccgatccgcttgggtaccatggcgtg
cttgccgcactgcgcgccggcggattcaccctcgccgagcgcaaaaggctggcgtcgtta
gcgtttcagcatatagccgagtacgacatcgccgtcgcgagctggatgcaacagacccta
gcgcccgaacatcctgttgccgcctttccgcagtggttcggccgaagctggcgccgcgtg
gcgatgctgcgctacggcgagaacccgcaccaacaggccgctctctacggcgaccccacc
gcctggccggggctggcccaggccgagcaactgcacggaaaagacatgtcctacaacaac
ttcaccgatgcggacgcagcctggcgggccgccttcgaccacgaacaaacgtgcgtggcg
atcatcaagcacgccaacccgtgcggcatcgcaatctcgtccgtttcggtcgccgacgcg
catcgcaaggctcacgaatgcgatccgctgagcgcctacggcggggtcatcgccgccaat
accgaggtcagtgtcgaaatggccgagtatgtgagcaccatcttcaccgaagtcatcgtc
gcgcctggctacgcccccggggccctcgatgtgctggcccgcaagaagaacatccgggtg
ctggtagccgccgagccactggccggtggcagcgagttgcgtccgatcagcggtggactg
ctgatacagcagagcgaccagcttgacgcgcacggtgacaacccggcgaactggaccttg
gcgaccgggtcacctgcggaccccgcgacgctgaccgacctggtcttcgcgtggcgagcc
tgccgtgcggtcaagtcgaacgcgatagtgatagctgccgacggcgccaccgtcggcgtc
gggatgggtcaggtcaaccgtgtcgacgccgcccggttggccgtcgaacgcggcggcgag
cgggttcgcggcgcggtggcagcctcggatgcgttcttcccctttcccgacggcctggaa
acgttggccgccgcgggggtcaccgcggtcgtccaccccggtggctcggtgcgcgacgag
gaagtgaccgaagcggcggccaaggccggtgtcaccctatatctcaccggggcgcggcac
ttcgcgcactga

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