KEGG   Macaca mulatta (rhesus monkey): 697580
Entry
697580            CDS       T01028                                 
Symbol
TYMS
Name
(RefSeq) thymidylate synthase
  KO
K00560  thymidylate synthase [EC:2.1.1.45]
Organism
mcc  Macaca mulatta (rhesus monkey)
Pathway
mcc00240  Pyrimidine metabolism
mcc00670  One carbon pool by folate
mcc01100  Metabolic pathways
mcc01232  Nucleotide metabolism
mcc01523  Antifolate resistance
Module
mcc_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:mcc00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    697580 (TYMS)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    697580 (TYMS)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    697580 (TYMS)
Enzymes [BR:mcc01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     697580 (TYMS)
SSDB
Motif
Pfam: Thymidylat_synt
Other DBs
NCBI-GeneID: 697580
NCBI-ProteinID: NP_001182436
Ensembl: ENSMMUG00000004046
Position
18:61963940..61976091
AA seq 313 aa
MPVAGSELPRPPLQPASQERDAEPRPPHGELQYLGQIEHILRCGVRKDDRTGTGTLSVFG
MQARYSLRGEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDS
LGFSAREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMC
AWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHI
TGLKPGDFVHTLGDAHIYLNHIEPLKIQLQREPRPFPKLKILRKVEKIDDFKAEDFQIEG
YNPHPTIKMEMAV
NT seq 942 nt   +upstreamnt  +downstreamnt
atgcccgtcgccggctcagagctgccgcgcccgcccttgcagcccgcctcacaggagcgg
gacgccgagccacggccgccgcacggagaactgcagtacctggggcagatcgagcacatc
ctccgctgcggcgtcaggaaggacgaccgcacgggcaccggcacgctgtcggtattcggc
atgcaggcgcgctacagcctgagaggtgaatttcctctgctgacaaccaaacgtgtgttc
tggaagggtgttttggaggagttgctgtggtttatcaagggatctacaaatgctaaagag
ctgtcttccaagggagtgaaaatctgggatgccaatggatcccgagactttttggacagc
ctggggttctccgccagagaagaaggggacttgggtccagtttatggcttccagtggagg
cattttggggcagaatacagagatatggaatcagattattcaggacagggagttgaccaa
ctacaaagagtgattgacaccatcaaaaccaaccctgacgacagaagaatcatcatgtgt
gcttggaatccaagagatcttcctctgatggcactgcctccatgccatgctctctgccag
ttctatgtggtgaacagtgagctgtcctgccagctgtaccagagatcgggagacatgggc
ctaggtgtgcctttcaacatcgccagctacgccctgctcacgtacatgattgcgcacatc
acgggcctgaagccaggtgactttgtacacactttgggagatgcacatatttacctgaat
cacatcgagccactgaaaattcagcttcagcgagaacccagacctttcccaaagctcaaa
attctccgaaaagttgagaaaattgatgacttcaaagctgaagactttcagattgaaggg
tacaatccgcatccaactattaaaatggaaatggctgtttag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (5)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (11)   
   RefSeq(nuc) (1)   
   GenBank (5)   
   EMBL (5)   
Protein domain (1)   
   Pfam (1)   
All databases (35)   

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