KEGG   MODULE: M00009
Entry
M00009            Pathway   Module                                 
Name
Citrate cycle (TCA cycle, Krebs cycle)
Definition
(K01647,K05942) (K01681,K01682) (K00031,K00030) ((K00164+K00658,K01616)+K00382,K00174+K00175-K00177-K00176) (K01902+K01903,K01899+K01900,K18118) (K00234+K00235+K00236+(K00237,K25801),K00239+K00240+K00241-(K00242,K18859,K18860),K00244+K00245+K00246-K00247) (K01676,K01679,K01677+K01678) (K00026,K00025,K00024,K00116)
Diagram
M00009

Orthology
K01647  
citrate synthase [EC:2.3.3.1] [RN:R00351]
K05942  
citrate (Re)-synthase [EC:2.3.3.3] [RN:R00351]
K01681,K01682  
aconitate hydratase [EC:4.2.1.3] [RN:R01325 R01900 R01324]
K00031,K00030  
isocitrate dehydrogenase [EC:1.1.1.42 1.1.1.41] [RN:R01899 R00268 R00267 R00709]
K00164,K01616,K00658,K00382  
2-oxoglutarate dehydrogenase complex [EC:1.2.4.2 2.3.1.61 1.8.1.4] [RN:R00621 R03316 R01700 R02570 R07618]
K00174  
2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] [RN:R01197]
K00175  
2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] [RN:R01197]
K00177  
2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3] [RN:R01197]
K00176  
2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3] [RN:R01197]
K01902,K01903  
succinyl-CoA synthetase [EC:6.2.1.5] [RN:R00405]
K01899,K01900  
succinyl-CoA synthetase [EC:6.2.1.4 6.2.1.5] [RN:R00405 R00432 R00727]
K18118  
succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18] [RN:R10343]
K00234,K00235,K00236,K00237,K25801  
succinate dehydrogenase [EC:1.3.5.1] [RN:R02164]
K00239,K00240,K00241,K00242,K18859,K18860  
succinate dehydrogenase / fumarate reductase [EC:1.3.5.1 1.3.5.4] [RN:R02164]
K00244,K00245,K00246,K00247 fumarate reductase [EC:1.3.5.4] [RN:R02164]  
 
K01676,K01679,K01677,K01678  
fumarate hydratase [EC:4.2.1.2] [RN:R01082]
K00026,K00025,K00024  
malate dehydrogenase [EC:1.1.1.37] [RN:R00342]
K00116  
malate dehydrogenase (quinone) [EC:1.1.5.4] [RN:R00361]
Class
Pathway modules; Carbohydrate metabolism; Central carbohydrate metabolism
Pathway
map00020  Citrate cycle (TCA cycle)
map01200  Carbon metabolism
map01100  Metabolic pathways
Reaction
R00351  
R01325+R01900,R01324  
R01899+R00268,R00267,R00709  
R00621+R03316,R01700  
R02570  
R07618  
R01197  
R00405,R00432,R00727,R10343  
R02164  
R01082  
R00342,R00361  
Compound
C00024  Acetyl-CoA
C00036  Oxaloacetate
C00158  Citrate
C00311  Isocitrate
C00026  2-Oxoglutarate
C15972  Enzyme N6-(lipoyl)lysine
C16254  [Dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine
C00091  Succinyl-CoA
C15973  Enzyme N6-(dihydrolipoyl)lysine
C00042  Succinate
C00122  Fumarate
C00149  (S)-Malate

  All links  
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (42)   
   KEGG ENZYME (20)   
   KEGG REACTION (22)   
Gene (42)   
   KEGG ORTHOLOGY (42)   
All databases (99)   

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