KEGG   Mannheimia haemolytica USDA-ARS-USMARC-184: B824_21520
Entry
B824_21520        CDS       T03786                                 
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
  KO
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
Organism
mhat  Mannheimia haemolytica USDA-ARS-USMARC-184
Pathway
mhat00290  Valine, leucine and isoleucine biosynthesis
mhat00660  C5-Branched dibasic acid metabolism
mhat01100  Metabolic pathways
mhat01110  Biosynthesis of secondary metabolites
mhat01210  2-Oxocarboxylic acid metabolism
mhat01230  Biosynthesis of amino acids
Module
mhat_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:mhat00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    B824_21520 (leuC)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    B824_21520 (leuC)
Enzymes [BR:mhat01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33  3-isopropylmalate dehydratase
     B824_21520 (leuC)
    4.2.1.35  (R)-2-methylmalate dehydratase
     B824_21520 (leuC)
SSDB
Motif
Pfam: Aconitase
Other DBs
NCBI-ProteinID: AJE08947
Position
2064636..2066054
AA seq 472 aa
MQQAKTLYQKLFDSHVVYEAEGETPIIYINRHLIHEVTSPQAFDGLRVAGRQVRQVSKTF
GTMDHSISTQVRDVQQLEGQAKIQVLELEKNCEETGIPLFDITKKQQGIVHVMGPEQGLT
LPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQARAKSMKVEVRGKVNPGI
TAKDIVLAIIGKTTMAGGTGYVVEFCGEAIRDLSMEGRMTVCNMAIEFGAKAGIVAPDET
TFAYLKDRPNAPKGQDWEDAIEYWKTLKADEGAVYDAEVILEAKDIAPQVTWGTNPGQVI
GIDDVIPNPEDMADPVTRASAEKALAYIGLEAHTDMKDVPVDQVFIGSCTNARIEDLRAA
AAVMKGRKKADNVKRILVVPGSGLVKEQAEKEGLDKIFIEAGAEWRNPGCSMCLGMNDDR
LGEWERCASTSNRNFEGRQGRNGRTHLVSPAMAAAAAVFGKFMDIRKVSLNA
NT seq 1419 nt   +upstreamnt  +downstreamnt
atgcaacaagccaaaaccctatatcaaaaactattcgactcacacgttgtgtatgaagcc
gaaggcgaaacgccgattatttatattaaccgccacttaattcacgaagttaccagcccg
caagcgtttgacggcttgcgtgttgccggtcgccaagttcgccaagtcagtaaaaccttc
ggcacaatggaccacagtatttcaacccaagtgcgtgatgtacagcaacttgaagggcaa
gcgaaaattcaagtattagaattagaaaaaaactgcgaagaaaccggtatcccactgttt
gacatcactaaaaaacaacaaggtatcgttcacgtaatggggccggagcaaggcttaact
ttacccggtatgaccattgtatgtggtgactcgcacaccgccactcacggggcctttggt
gcgttagccttcggtatcggtacttccgaagtggaacacgttttagccacccaaacctta
aaacaggcccgtgcaaaaagtatgaaagtggaagtccgtggcaaagtaaacccgggcatt
accgcaaaagatattgtgcttgcgatcatcggtaaaacaactatggctggcggtacaggc
tatgtagtggaattttgtggcgaagcaattcgtgatctttcaatggaagggcgaatgaca
gtgtgtaatatggcgattgagtttggtgcgaaagccggtattgttgccccggatgaaacc
acgttcgcttacttgaaagaccgcccaaatgcaccaaaaggtcaagattgggaagatgcc
attgaatattggaaaaccctcaaagccgatgagggtgcagtttacgatgcggaagtgatc
ttagaagcaaaagacattgctccacaagtgacttggggaaccaacccggggcaggtgatc
ggtattgatgatgtaattccaaatccggaagatatggccgatcctgttactcgtgcctct
gcggaaaaagccttagcttacatcggcttagaagcccatacagatatgaaagatgtaccg
gttgatcaagtctttattggttcttgtactaatgctcgtattgaagatttgcgtgctgcg
gcagcagtaatgaaagggcgtaaaaaagccgacaatgtaaaacgtattctcgttgtgcca
ggttcaggtttggtaaaagagcaagcagaaaaagagggcttggataaaatcttcattgaa
gccggtgcagaatggcgtaacccgggttgctcaatgtgtttgggaatgaacgatgaccgc
ttgggcgaatgggaacgttgtgcctctacgtctaaccgtaactttgagggcagacaagga
cgtaacggtcgtacccacttagtcagcccggcaatggcggctgcggcggcggtgttcggt
aaatttatggatattcgcaaagtgtcattaaacgcataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (6)   
   KEGG MODULE (2)   
Chemical substance (19)   
   KEGG COMPOUND (19)   
Chemical reaction (13)   
   KEGG ENZYME (2)   
   KEGG REACTION (11)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (1)   
   Pfam (1)   
All databases (47)   

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