KEGG   Micromonospora sp. L5: ML5_4402
Entry
ML5_4402          CDS       T01379                                 
Name
(GenBank) Beta-ketoacyl synthase
  KO
K05551  minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
Organism
mil  Micromonospora sp. L5
Pathway
mil00253  Tetracycline biosynthesis
mil01056  Biosynthesis of type II polyketide backbone
mil01100  Metabolic pathways
mil01110  Biosynthesis of secondary metabolites
Module
mil_M00778  Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:mil00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01056 Biosynthesis of type II polyketide backbone
    ML5_4402
   00253 Tetracycline biosynthesis
    ML5_4402
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:mil01004]
    ML5_4402
   01008 Polyketide biosynthesis proteins [BR:mil01008]
    ML5_4402
Enzymes [BR:mil01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.235  tetracenomycin F2 synthase
     ML5_4402
    2.3.1.260  tetracycline polyketide synthase
     ML5_4402
Lipid biosynthesis proteins [BR:mil01004]
 Polyketide synthase
  Component type
   ML5_4402
Polyketide biosynthesis proteins [BR:mil01008]
 Polyketide synthase (PKS)
  Type II PKS
   C7-C14 cyclized polyketide type
    Octaketide PKS
     ML5_4402
    Nonaketide PKS
     ML5_4402
    Decaketide PKS
     ML5_4402
SSDB
Motif
Pfam: ketoacyl-synt Ketoacyl-synt_C Thiolase_N AAT
Other DBs
NCBI-ProteinID: ADU09879
Position
4679020..4680291
AA seq 423 aa
MSQRRVVITGIGVVAPGGLGAKAFWERIVAGTPMTRLITAFDSTDFRSRIAAECDFDPFQ
YGFSEHDIGRLDRAALFALTATREAMSDSGLVVDRDDAHRVGVSLGTAVGATLRLEERYR
AVSHEGRDWLVDHRLAGPDLYDYFVPSSMAAEVAWAAGAEGPNAVVSAGCTSGIDAVGHA
WDLIRDGSVDMMIAGATDAPIAPITVACFDAIKATSNTNDDPGTAARPFDRTRNGFVLGE
GSAVLVLEELQSARRRDAHIYAEIRGYASRGNAFHMTGLRPDGQEMAAAIRAALDTARIP
ATAVDYVNAHGTATRQNDRHETQALKRGLGMHAYDVPISSIKPVIGHSLGAVGAIEVAAS
AMAIEFDVVPPTANLHHPDAELDLDYVPREARQRKLSTVLTVGSGFGGFQSAMVLSAPEA
VAA
NT seq 1272 nt   +upstreamnt  +downstreamnt
gtgagtcaacgtcgggtcgtcatcaccgggatcggcgtcgtcgcgcccggcgggttggga
gcgaaggccttctgggaacgcatcgtggcgggcaccccgatgacccgcctgatcaccgcc
ttcgactccaccgacttccggtcgcggatcgctgccgagtgtgacttcgatccgttccag
tacggcttcagcgagcacgacatcgggcgcttggaccgggccgccctgttcgcgctcacc
gccacgcgggaggcgatgagcgacagcggcctcgtcgtcgaccgcgacgacgcgcaccgg
gtcggggtgagtctcggtaccgccgttggcgccacgctgcggttggaggagcgctaccgc
gcggtcagccacgaagggcgcgactggctcgtcgaccaccggctcgccggccccgacctg
tacgactacttcgtgcccagctcgatggcggccgaggtggcctgggccgccggcgcggaa
ggacccaacgccgtcgtgtcggccgggtgcacctccggcatcgacgcggtgggacacgcc
tgggacctcatccgcgacggatcggtcgatatgatgatcgccggcgccaccgacgcgccg
atcgcgccgatcacggttgcctgcttcgacgccatcaaggccacgtccaacaccaacgac
gatccaggcaccgccgcgcggccgttcgaccgtacgcgtaacgggttcgtgctcggcgag
ggctcggcggtcctggtcttggaggaactgcagagcgcgcgccgccgcgacgcgcacatc
tacgccgagatccgcgggtacgcctcccgtggcaacgccttccacatgaccggcctgcgg
cccgacgggcaggagatggccgcggcgatccgcgccgccctcgacaccgcccgcatcccg
gccaccgccgtcgactacgtcaatgcgcacggcaccgcgaccagacagaacgaccgccac
gagacccaggcgctcaagcggggcctcggcatgcacgcctacgacgtgccgatcagctcc
atcaagccggtcatcggacactcgctcggcgccgtcggagcgatcgaggtcgccgccagc
gcgatggcgatcgagttcgacgtcgtgccaccgacggccaacctccaccaccccgacgcg
gagctggacctggactacgtgccacgcgaggccaggcagcgcaagctctccacagtgctg
accgtgggcagcggcttcggcggattccaaagcgcgatggtgctctccgcgcccgaggcg
gtggcagcatga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (18)   
   KEGG COMPOUND (18)   
Chemical reaction (12)   
   KEGG ENZYME (2)   
   KEGG REACTION (10)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (4)   
   Pfam (4)   
All databases (47)   

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