KEGG   Mycobacterium leprae Br4923: MLBr01095
Entry
MLBr01095         CDS       T00842                                 
Symbol
odhA
Name
(GenBank) 2-oxoglutarate dehydrogenase, E1 and E2 components
  KO
K01616  multifunctional 2-oxoglutarate metabolism enzyme [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
Organism
mlb  Mycobacterium leprae Br4923
Pathway
mlb00020  Citrate cycle (TCA cycle)
mlb00630  Glyoxylate and dicarboxylate metabolism
mlb00785  Lipoic acid metabolism
mlb01100  Metabolic pathways
mlb01110  Biosynthesis of secondary metabolites
mlb01120  Microbial metabolism in diverse environments
mlb01200  Carbon metabolism
mlb01210  2-Oxocarboxylic acid metabolism
Module
mlb_M00009  Citrate cycle (TCA cycle, Krebs cycle)
mlb_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:mlb00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00020 Citrate cycle (TCA cycle)
    MLBr01095 (odhA)
   00630 Glyoxylate and dicarboxylate metabolism
    MLBr01095 (odhA)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    MLBr01095 (odhA)
Enzymes [BR:mlb01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.2  oxoglutarate dehydrogenase (succinyl-transferring)
     MLBr01095 (odhA)
 2. Transferases
  2.2  Transferring aldehyde or ketonic groups
   2.2.1  Transketolases and transaldolases
    2.2.1.5  2-hydroxy-3-oxoadipate synthase
     MLBr01095 (odhA)
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.61  dihydrolipoyllysine-residue succinyltransferase
     MLBr01095 (odhA)
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.71  2-oxoglutarate decarboxylase
     MLBr01095 (odhA)
SSDB
Motif
Pfam: E1_dh 2-oxoacid_dh OxoGdeHyase_C Transket_pyr 2-oxogl_dehyd_N DUF5724
Other DBs
NCBI-ProteinID: CAR71190
UniProt: A0A0H3MQC7
Position
complement(1260068..1263850)
AA seq 1260 aa
MQKVASVAQCACRTEELRRTAAVANISSPFGQNEWLVEEMYRKFRDDPSSVDPSWHEFLV
DYNPESTAEPVLTDPTSTDKQPSATPQAKPAAAADPVASRAKPATTPTVANGTAAGSAAA
PAKTTTTPPIEGDELQVLRGAAAVVVKNMSASLDVPTATSVRAVPAKLMIDNRTVINNQL
KRNRGGKISFTHLLGYALVQAVKKFPNINRHYAEIDGKPIAVTPAHTNLGLAIDLQGKDG
KRSLVVAGIKRCEELRFAQFVTAYEDIVRRARDGKLTAEDFAGVTISLTNPGTIGTVHSV
PRLMTGQGAIIGVGAMEYPAEFQGASAERIAELGIGKLITLTSTYDHRIIQGAESGDFLR
TIHEMVLSDSFWDEIFRELSIPYLPVRWRTDNPDSIVDKNARVMELIAAYRNRGHLMADI
DPLRLDNTRFRSHPDLDLLTHGLTLWDLDRVFKVNGFGGWKYKKLRDVLGLLRDAYCRHI
GVEYTHILDPEQQEWLQQRVETKNVKPTVAEQKYILSKLNAAEAFETFLHTKYVGQKRFS
LEGAESVIPMMDAAIDQCAKHGLDEVVIGMPHRGRLNVLANIVGKPYSQIFTEFEGNLNP
TLAHSSGDVKYHLGATGLYLQMFGDNDIQVSLTANPSHLEAVDPVLEGLVRAKQDLLNKD
TNGNQDEAFSVVPMMLHGDAAFAGQGVVAETLNLANLPGYRVGGTIHIIVNNQIGFTTAP
EYSRSSEYCTDVAKMIGAPIFHVNGDDPEACVWVAKLAVDFRQRFKKDVVIDMLCYRRRG
HNEGDDPSMTNPYMYDVVDTKRGARKSYTEALIGRGDISLKEAEDALRDYQGQLERVFNE
VRDLEKHGVQPSESVESDQMIPAGLSTAVDKALLARIGDAFLAVPEGFTVHPRVQPVLEK
RREMAYEGKIDWAFAELLALGSLVAEGKLVRLSGQDTKRGTFSQRHSVIIDRHTGEEFTP
LQLLANNPDGSPTGGKFLVYNSPLSEYAAVGFEYGYTVGNPDAVVLWEAQFGDFVNGAQS
IIDEFINSGEAKWGQLSTVVLLLPHGHEGQGPDHTSGRIERFLQLWAEGSMTFAVPSTPS
NYFHLLRRHALDGIKRPLIVFTPKSMLRNKAAVSDIKDFTEIKFRSVLEEPTYEDSIDDR
SKVTRVLLTCGKLYYELAARKIKDNRDDVAIVRIEQLAPLPRRRLGETLDRYENAKEFFW
VQEEPANQGAWPRFGLELPELLPRLTGIKRISRRAMSAPSSGSSKVHAVEQQEILDTAFG
NT seq 3783 nt   +upstreamnt  +downstreamnt
gtgcagaaagttgcaagtgtcgcgcaatgcgcttgcaggacagaagaattgaggcgaaca
gcggccgtggccaacataagttcaccattcgggcaaaacgaatggttggtcgaagagatg
taccgcaagttccgcgacgacccctcctcggtcgatccgagctggcacgaattcctggtt
gactacaatcccgaatcaaccgccgaaccggtacttacggaccctacctccactgataaa
caaccctcagccacgccacaagcaaagccagctgcggcagctgacccggtagcgagcagg
gccaagcccgcgaccaccccaacagtagcgaacggcacggcagccggctctgccgcagct
ccagccaaaaccaccactaccccgcctatcgaaggtgacgagttgcaggtgctgcgcggt
gccgccgcagtggtcgtcaaaaatatgtccgcgtcgctggacgtgccgacggcgaccagt
gtgcgagccgttccagccaagctgatgatcgacaaccggaccgtcatcaacaaccagctc
aagcgcaaccgcggcgggaagatctccttcacgcatttgctgggctacgcgttagtgcag
gcggtcaagaagttcccgaacatcaaccggcactacgcggagatcgacggcaaacccatc
gcagtgacaccggcccacaccaatctcggcctagcgatcgacctgcaaggtaaagacggc
aagcggtccttggtggtggccggtatcaagcgctgcgaagaattgcgattcgcacagttc
gtcaccgcctacgaagatatcgtccgccgggcgcgcgacggtaagctgaccgccgaagac
tttgccggcgtcacgatttcacttaccaaccccggcactatcggcaccgtgcattcggtg
ccgcggctgatgactggccagggcgccatcatcggcgtgggcgccatggaataccccgcc
gagtttcaaggcgccagcgcggagcgcatcgccgaattgggtatcggcaaactgatcacc
ctaacttcaacctacgaccaccgcatcatccagggtgcggaatcaggtgacttcctgcgc
acgatccacgaaatggtgctctcggacagcttctgggacgaaatctttcgcgagctgagc
atcccgtatctgccggtgcgctggcgcaccgacaacccggactcgatcgtcgacaagaac
gctcgcgtcatggagttgatcgcggcctaccgtaaccgcggccatctaatggccgatatc
gacccgctgcggttggacaacacccgcttccgcagtcaccctgacctcgatttgctaacc
cacggcctgacgctgtgggatctggatcgggtattcaaagtcaacggctttggcgggtgg
aaatacaagaaactgcgtgacgtgctgggcttgcttcgcgacgcctactgccgccacatc
ggcgtggaatacacccacatcctcgaccccgaacaacaggaatggctgcaacagcgggtc
gagaccaagaacgtcaaaccgactgtggccgaacagaaatacatcctgagcaagctcaac
gctgccgaagccttcgaaacgttcctgcatactaagtacgtcgggcagaaacgtttctcg
ctagaaggcgccgaaagcgttatcccgatgatggatgcggcgatcgaccagtgcgccaag
catggcctggacgaagtggtcatcgggatgccacaccgcggccggctcaacgtattggcc
aacatcgtcggcaagccgtactcacagatcttcaccgaattcgagggcaatctaaaccca
acactagcgcacagctctggtgacgtcaaataccacctcggtgctaccggtttgtatctg
cagatgttcggcgacaacgacattcaagtatcgctgaccgccaacccttcacacttggaa
gccgtggaccccgtgctcgaaggtctcgtccgggccaagcaggatctactcaacaaggat
accaatggcaaccaagatgaagcgttttcggtggtgccaatgatgctgcacggggacgct
gccttcgccggccaaggagtcgttgccgaaacgctaaacttggcgaacctgcctggttac
cgggtcggcggcaccatccacatcatcgtcaacaaccagatcggcttcactaccgcgccg
gagtactccagatccagcgagtactgcacggatgtcgccaagatgatcggcgcgccgatc
ttccacgtcaacggtgatgacccggaagcctgcgtgtgggtagccaagctggcggtcgac
tttcggcagcgttttaaaaaggacgtcgttatcgacatgctgtgctaccgccggcgcggg
cacaatgagggcgacgatccgtcgatgacgaacccgtacatgtacgacgttgtcgacacc
aagcgcggcgcccgtaagagttacaccgaagccttgatcggccgtggcgacatttccttg
aaggaagccgaggacgcgctgcgcgactaccaaggccagctggagcgggtgttcaacgag
gtacgcgacctggaaaagcacggcgtgcagcccagcgagtcagtggagtctgaccagatg
atccctgcgggtttgtccaccgcggtggacaaagcactgctggcccgcatcggcgacgcc
ttcctggcggtaccagaaggtttcaccgtgcacccgcgggtgcagccggtgctcgagaaa
cgccgggagatggcttatgaaggcaagatcgactgggctttcgccgagttgctagcctta
gggtcgctggtggcggaaggcaaattggtgcggctgtccggccaagacaccaagcgtggc
accttctcgcagcggcattcggtgatcatcgaccgccacaccggcgaggaattcactccg
ttacagctgctggccaataaccccgacggcagtcccaccggcggcaagtttctggtctac
aactcgccactgtcggagtatgccgctgtcggtttcgagtacggctatacggtaggcaac
ccggatgccgtggtgctgtgggaggcgcagttcggcgacttcgtcaacggcgcacagtca
atcatcgacgaattcatcaactccggtgaggccaagtggggacagttgtcgacagtggtg
ctgctattgccgcacgggcacgaagggcagggccctgaccacacctctggccgcatcgaa
cgcttcctgcagctgtgggcggagggctcaatgacctttgcggtgccgtcgactccatct
aactacttccacttgctgcgccggcacgctctcgacggcattaaacgtccactgatcgtg
ttcacgcccaagtcgatgttgcgcaacaaggccgcagtcagtgatatcaaggacttcacc
gagatcaagttccgttcggtgctggaggaacccacctacgaggacagcatcgacgaccgc
agcaaggtcaccagggtcctgttgacctgcggcaagctctactacgagctggccgcccgc
aagatcaaggacaaccgcgacgacgtcgcgatcgtgcggatcgaacagctggccccgctg
ccgcggcgccggctcggcgaaacgctggaccgctacgagaacgccaaagagttcttctgg
gtgcaagaggagccagccaatcaaggtgcctggccgcggttcggcctggagctgcccgag
ctgctgccccgactcaccgggatcaagaggatttcgcggcgggccatgtcggcgccgtcg
tcgggttcgtcgaaggtgcatgccgtcgagcaacaggagatcctcgacaccgcgttcggc
taa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (8)   
   KEGG MODULE (2)   
Chemical substance (14)   
   KEGG COMPOUND (14)   
Chemical reaction (10)   
   KEGG ENZYME (4)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (6)   
   Pfam (6)   
All databases (47)   

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