KEGG   Methanococcus maripaludis OS7: MMOS7_11720
Entry
MMOS7_11720       CDS       T03693                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
mmao  Methanococcus maripaludis OS7
Pathway
mmao00290  Valine, leucine and isoleucine biosynthesis
mmao00620  Pyruvate metabolism
mmao01100  Metabolic pathways
mmao01110  Biosynthesis of secondary metabolites
mmao01210  2-Oxocarboxylic acid metabolism
mmao01230  Biosynthesis of amino acids
Module
mmao_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:mmao00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    MMOS7_11720 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    MMOS7_11720 (leuA)
Enzymes [BR:mmao01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     MMOS7_11720 (leuA)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: BAP63258
UniProt: A0A2Z5PKD4
Position
1146199..1147743
AA seq 514 aa
MESYLNSNEIIKNSLKSMKLPEKVRVFDTTLRDGEQTPGVSLMPDQKMDIAKNLSEIGVD
AIEAGFPVSSEGEQESIKNITSLGLDAEICGLARAVKKDIDVAIDCGVDSIHTFIATSPL
HREYKLKMSKEKIIDIAVESIEYIKEHGVIVEFSAEDATRTELDYLKEVYKKAVEAGADR
INVPDTVGVMVPNSMSYLIKELKNDIKVPISVHCHNDFGIAVSNSVAAVEAGAEQVHCTV
NGLGERAGNASLEETVMTLNMVYGINTNVTTKMLTKLSKLVSHYTGIKTQPNKAIVGENS
FAHESGIHAHGVLANALTYEPIDPEIVGNRRRIVLGKHSGAHAIKSKLSEIGVEVGEIVS
EEQFCEIVERVKAIGDKGKIVTDADVMAIAEDITKRTLKSERIVDLEQFAVITGNHVLPT
ASVALKVKDKIYKTSELGVGPVDAALKAIQAAVGENIRLNEYNISAISGGTDAIAEVTVR
LENQEKEVIAKATGDDVVKASVEAVIDGINKLMG
NT seq 1545 nt   +upstreamnt  +downstreamnt
atggaatcttatttaaacagcaatgaaattatcaaaaactccctaaaatcaatgaaactg
ccagaaaaagtacgtgtttttgacactacgctaagggatggagaacagactccgggagta
tccctaatgcctgatcaaaaaatggatattgcaaaaaatctaagtgaaatcggtgttgat
gcaatagaagcaggctttccagtttcttctgaaggagaacaggaatctattaaaaatata
acatccctagggctggatgcagaaatttgcggacttgcaagggctgttaaaaaagatata
gatgttgcaattgactgtggggttgacagtatccacacatttattgctacatccccgcta
cacagggaatacaaattaaaaatgagtaaagaaaagattatcgacattgcagttgaatct
atcgaatatataaaagaacatggcgtaattgtagaattttccgcggaagacgctacaaga
actgaactcgattacttaaaagaagtttacaaaaaagcagttgaagctggagctgacagg
ataaacgttccagataccgttggtgttatggttccaaattcgatgtcctatttaataaaa
gaattaaaaaacgatataaaagttccaatatccgtacactgccacaatgactttggaatt
gctgtatcaaactctgttgcagcagttgaagctggagctgaacaggtacactgtactgta
aacggccttggtgaaagagcaggaaacgcgtcactagaagaaaccgtgatgactttaaac
atggtttatggaattaatactaatgtaactacaaaaatgttaacaaaactctcaaaactg
gtttcgcactacaccggaattaaaacacagcctaataaggcaattgttggtgaaaattca
tttgcacacgaaagtggaattcacgcacacggtgttttagcaaatgcattaacatacgaa
ccaattgatccagaaatagttggaaacagacgtagaattgttcttggaaaacacagcggt
gctcacgcgataaaatcaaaactctcagaaatcggtgttgaagttggagaaatcgtttca
gaagagcagttctgtgaaatagttgaaagagtaaaagcaattggcgataaaggaaaaatc
gtgacagatgcggatgtaatggcaattgcagaagatattaccaaaagaacattaaaatct
gaaagaatagtggatttagaacagtttgcagtaattactggaaatcatgtgcttccaacc
gcaagcgttgcattaaaagtaaaagataaaatttataaaacgtctgaacttggagtagga
cctgttgatgctgcactaaaagcaattcaagccgcagttggtgaaaatatccgattaaac
gaatacaacatcagcgcaatttctggaggaactgacgccattgcagaagttacagttaga
cttgaaaatcaagaaaaagaagttatagcaaaagctactggcgatgacgttgttaaagca
tccgtagaagcagttatcgatggaataaacaaattaatgggttaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (2)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (22)   

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