KEGG   Marmota marmota marmota (Alpine marmot): 107142960
Entry
107142960         CDS       T09644                                 
Symbol
Ptk2
Name
(RefSeq) focal adhesion kinase 1 isoform X22
  KO
K05725  focal adhesion kinase 1 [EC:2.7.10.2]
Organism
mmma  Marmota marmota marmota (Alpine marmot)
Pathway
mmma01522  Endocrine resistance
mmma04012  ErbB signaling pathway
mmma04062  Chemokine signaling pathway
mmma04148  Efferocytosis
mmma04151  PI3K-Akt signaling pathway
mmma04360  Axon guidance
mmma04370  VEGF signaling pathway
mmma04510  Focal adhesion
mmma04670  Leukocyte transendothelial migration
mmma04810  Regulation of actin cytoskeleton
mmma04935  Growth hormone synthesis, secretion and action
mmma05100  Bacterial invasion of epithelial cells
mmma05135  Yersinia infection
mmma05146  Amoebiasis
mmma05163  Human cytomegalovirus infection
mmma05165  Human papillomavirus infection
mmma05170  Human immunodeficiency virus 1 infection
mmma05200  Pathways in cancer
mmma05202  Transcriptional misregulation in cancer
mmma05205  Proteoglycans in cancer
mmma05208  Chemical carcinogenesis - reactive oxygen species
mmma05222  Small cell lung cancer
mmma05417  Lipid and atherosclerosis
mmma05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmma00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    107142960 (Ptk2)
   04370 VEGF signaling pathway
    107142960 (Ptk2)
   04151 PI3K-Akt signaling pathway
    107142960 (Ptk2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    107142960 (Ptk2)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    107142960 (Ptk2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    107142960 (Ptk2)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    107142960 (Ptk2)
   04062 Chemokine signaling pathway
    107142960 (Ptk2)
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    107142960 (Ptk2)
  09158 Development and regeneration
   04360 Axon guidance
    107142960 (Ptk2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    107142960 (Ptk2)
   05202 Transcriptional misregulation in cancer
    107142960 (Ptk2)
   05205 Proteoglycans in cancer
    107142960 (Ptk2)
   05208 Chemical carcinogenesis - reactive oxygen species
    107142960 (Ptk2)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    107142960 (Ptk2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    107142960 (Ptk2)
   05163 Human cytomegalovirus infection
    107142960 (Ptk2)
   05165 Human papillomavirus infection
    107142960 (Ptk2)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    107142960 (Ptk2)
   05100 Bacterial invasion of epithelial cells
    107142960 (Ptk2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    107142960 (Ptk2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    107142960 (Ptk2)
   05418 Fluid shear stress and atherosclerosis
    107142960 (Ptk2)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    107142960 (Ptk2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmma01001]
    107142960 (Ptk2)
   01009 Protein phosphatases and associated proteins [BR:mmma01009]
    107142960 (Ptk2)
Enzymes [BR:mmma01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     107142960 (Ptk2)
Protein kinases [BR:mmma01001]
 Non-receptor tyrosine kinases
  FAK family
   107142960 (Ptk2)
Protein phosphatases and associated proteins [BR:mmma01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     107142960 (Ptk2)
Motif
Pfam: PK_Tyr_Ser-Thr Focal_AT Pkinase FERM_N_2 FERM_C_FAK1 FERM_M Kinase-like Haspin_kinase FERM_F2 GIT1_C ABC1
Other DBs
NCBI-GeneID: 107142960
NCBI-ProteinID: XP_015342006
Ensembl: ENSMMMG00000005381
Position
Unknown
AA seq 1062 aa
MAAAYLDPNLNHTPHSSAKTHLGPGMERSPGAMERVLKVFHYFESNNEPTTWASIIRHGD
ATDVRGIIQKIVDSHRVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEW
KYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSY
WEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESI
LKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFNQVQ
TIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLSIAENMADLIDGYCRLVSGATQSFII
RPQREGERALPSIPKLANSEKQGVRTHAVSVSETDDYAEIIDEEDTYTMPSKNYGIDEAR
DYEIQRERIELGRCIGEGQFGDVHQGVYMSPENPALAVAIKTCKNCTSDSVREKFLQEAL
TMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTA
LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPES
INFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYS
LMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPP
KPSRPGYPSPRSSEGFYPSPQHMVQSNHYQVSGYPGPHGLTAMAGSIYPGPASLLDQSES
WNHRPQEIPLWQPNMEDSASLDLRGMGQVLPAHLMEERLIRQQQEMEEDQRWLEKEERFL
KPDVRLSRGSIDREDGSLQGPTGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSS
PGDSYNEGVKPWRLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEY
VPMVKEVGLALRTLLATVDETIPVLPASTHREIEMAQKLLNSDLGELISKMRLAQQCAMT
SLQQEYKKQMLTAAHALAVDAKNLLDAIDQARLKMLGQARPH
NT seq 3189 nt   +upstreamnt  +downstreamnt
atggcagctgcttaccttgaccccaacttgaaccacacgccacactcaagtgctaagacc
cacctgggtcctggcatggaacgttcccctggtgccatggagcgagtattgaaggtcttt
cattattttgaaagcaataatgagccaaccacctgggccagtattatcaggcacggagat
gctactgatgtcaggggcatcatccagaagatagtggacagccacagagtgaagcatgtg
gcttgctacgggttccgcctcagccacctgcggtcggaggaggttcactggctgcatgtg
gacatgggtgtctccagcgtgagggagaagtatgagcttgcccatcctccggaggagtgg
aaatatgaattaaggattcgttacttgccaaaaggatttctgaaccagtttactgaagac
aagccaactctgaatttcttctaccaacaggtaaagagcgactacatgctagagatagca
gaccaagtggaccaggaaattgctttgaagttgggttgcctagaaatacggcgatcatac
tgggagatgcgcggcaatgcactggaaaagaagtctaactatgaagtgttagaaaaagat
gttggtttaaagcgattttttcctaagagtttactggattctgtcaaggccaaaacttta
agaaaactgatccaacaaacatttagacagtttgccaaccttaatagagaagaaagtatt
ctgaaattctttgagatcctctctccagtgtacagatttgataaagaatgcttcaagtgt
gccctggggtcaagctggattatttcagtggaactggcaatcggccccgaagaagggatc
agttacctaacagacaagggctgcaatcccacacatctggctgacttcaaccaagtgcag
accattcagtattccaacagtgaagacaaagacagaaaaggaatgctacagctcaaaatc
gcaggtgcccccgagcctctgacagtgacagccccatccctgagcatcgccgagaacatg
gcggacctaatagacgggtactgccggctggtgagcggagccacgcagtccttcatcatc
agacctcagagagaaggtgaacgggcattgccatcaatacccaaattggccaacagtgag
aagcaaggtgtacggacacatgccgtctctgtgtcagagacagacgactatgccgagata
atcgatgaagaagatacttacaccatgccctcaaaaaactatggaatagatgaagctagg
gactatgagattcaaagagaaagaatagaactcggacgctgtattggagaaggccagttt
ggagatgtgcatcaaggcgtgtacatgagtccagagaatccagctttggctgtcgcaatt
aaaacatgtaaaaactgtacttcggacagcgtgagagagaaattcctccaagaagcctta
acaatgcgtcagtttgaccatcctcacattgtgaagttgattggcgtcatcacagagaac
cccgtgtggataatcatggagctgtgcacactgggagagctgaggtcatttttgcaagta
aggaaatacagcttggatctggcatctctgatcttatatgcctatcagctcagtaccgca
ctggcatatctggagagcaaaagatttgtacacagggacattgctgctcgaaatgtcctg
gtatcctcaaatgattgtgtaaaattaggagacttcggattatctcggtacatggaagac
agtacttactacaaagcttccaaaggaaaattgcctattaaatggatggctccagagtca
atcaattttcgacgttttacctcagctagtgacgtgtggatgtttggtgtatgtatgtgg
gagattctgatgcatggtgtgaagccttttcaaggagtgaagaacaatgatgtgatcggt
cgaattgaaaatggggaaagattaccaatgcctccaaattgtcctcctaccctctacagc
cttatgacgaaatgctgggcctatgaccccagcaggcggcccaggtttactgaacttaaa
gcgcagctcagcacgatcctggaggaagagaaggctcagcaggaagaacggatgaggatg
gagtccagaagacaggccaccgtgtcttgggactctggagggtccgacgaagcaccaccc
aagcccagcagacctggttaccctagtccgcgctccagtgaaggattttaccccagcccg
cagcacatggtgcagagcaatcattatcaggtctctggctaccctggtccacacggactc
acagccatggctggcagcatctaccccggcccagcatctctcttggaccaatcagaatcg
tggaatcacaggccccaggagatacccctgtggcagcccaacatggaggactcagcatcg
ttggacctgagaggaatggggcaggtgttgcccgcccacctgatggaagagcgactgatc
cgacagcagcaggaaatggaagaagatcagcgctggctggagaaagaggagagatttctg
aaacctgatgtgaggctatctcgaggcagcattgacagggaggacgggagtcttcagggg
ccgactggaaaccaacacatctatcagcctgtgggcaaaccagatcctgcggctccacca
aagaaacctccacgccccggagcccccggccacctgggcagcctcgccagcctcagcagc
cctggggacagctacaacgagggtgtcaagccatggaggcttcaaccccaggaaatcagt
ccccctcccactgccaacctggaccggtccaatgacaaggtgtatgagaacgtgacgggc
ctggtgaaagctgtcattgagatgtccagtaaaatccagccagccccacccgaggagtac
gtccctatggtgaaggaagttggcttggccctgcggacactattggctaccgtggatgag
accattcctgtcctcccagccagcacacaccgagagatcgagatggcacagaagctgctc
aactctgacctgggagagctcatcagcaagatgcggctggcccagcagtgcgccatgacc
agcctgcagcaggagtacaagaagcagatgctgactgccgcccacgccctcgcagtggat
gccaagaacctgctggatgccattgaccaggcgagactgaagatgcttgggcaggcaagg
ccacattga

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (24)   
   KEGG PATHWAY (24)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
Protein sequence (37)   
   RefSeq(pep) (37)   
DNA sequence (37)   
   RefSeq(nuc) (37)   
Protein domain (11)   
   Pfam (11)   
All databases (119)   

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