KEGG   Mus musculus (mouse): 12367Help
Entry
12367             CDS       T01002                                 

Gene name
Casp3, A830040C14Rik, AC-3, CASP-3, CC3, CPP-32, CPP32, Lice, SCA-1, Yama, mldy
Definition
(RefSeq) caspase 3 (EC:3.4.22.56)
  KO
K02187  
caspase 3 [EC:3.4.22.56]
Organism
mmu  Mus musculus (mouse)
Pathway
Platinum drug resistance
MAPK signaling pathway
p53 signaling pathway
Apoptosis
Apoptosis - multiple species
Natural killer cell mediated cytotoxicity
TNF signaling pathway
Serotonergic synapse
Non-alcoholic fatty liver disease (NAFLD)
AGE-RAGE signaling pathway in diabetic complications
Alzheimer's disease
Parkinson's disease
Amyotrophic lateral sclerosis (ALS)
Huntington's disease
Pertussis
Legionellosis
Toxoplasmosis
Amoebiasis
Tuberculosis
Hepatitis B
Herpes simplex infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
MicroRNAs in cancer
Colorectal cancer
Viral myocarditis
Module
Apoptotic machinery
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    12367 (Casp3)
   04668 TNF signaling pathway
    12367 (Casp3)
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    12367 (Casp3)
   04215 Apoptosis - multiple species
    12367 (Casp3)
   04115 p53 signaling pathway
    12367 (Casp3)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    12367 (Casp3)
  Nervous system
   04726 Serotonergic synapse
    12367 (Casp3)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    12367 (Casp3)
   05206 MicroRNAs in cancer
    12367 (Casp3)
   05205 Proteoglycans in cancer
    12367 (Casp3)
   05203 Viral carcinogenesis
    12367 (Casp3)
   05210 Colorectal cancer
    12367 (Casp3)
  Neurodegenerative diseases
   05010 Alzheimer's disease
    12367 (Casp3)
   05012 Parkinson's disease
    12367 (Casp3)
   05014 Amyotrophic lateral sclerosis (ALS)
    12367 (Casp3)
   05016 Huntington's disease
    12367 (Casp3)
  Cardiovascular diseases
   05416 Viral myocarditis
    12367 (Casp3)
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    12367 (Casp3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    12367 (Casp3)
  Infectious diseases
   05133 Pertussis
    12367 (Casp3)
   05134 Legionellosis
    12367 (Casp3)
   05152 Tuberculosis
    12367 (Casp3)
   05161 Hepatitis B
    12367 (Casp3)
   05168 Herpes simplex infection
    12367 (Casp3)
   05146 Amoebiasis
    12367 (Casp3)
   05145 Toxoplasmosis
    12367 (Casp3)
  Antineoplastic resistance
   01524 Platinum drug resistance
    12367 (Casp3)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.56  caspase-3
     12367 (Casp3)
Peptidases [BR:mmu01002]
 Cysteine Peptidases
  Family C14: caspase family
   12367 (Casp3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
MGI: 
Ensembl: 
UniProt: 
Position
8 B1.1; 8 26.39 cM
AA seq 277 aa AA seqDB search
MENNKTSVDSKSINNFEVKTIHGSKSVDSGIYLDSSYKMDYPEMGICIIINNKNFHKSTG
MSSRSGTDVDAANLRETFMGLKYQVRNKNDLTREDILELMDSVSKEDHSKRSSFVCVILS
HGDEGVIYGTNGPVELKKLTSFFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSGTDE
EMACQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCSMLKLYAHKLEFMHILTRVN
RKVATEFESFSLDSTFHAKKQIPCIVSMLTKELYFYH
NT seq 834 nt NT seq  +upstreamnt  +downstreamnt
atggagaacaacaaaacctcagtggattcaaaatccattaataattttgaagtaaagacc
atacatgggagcaagtcagtggactctgggatctatctggacagtagttacaaaatggat
tatcctgaaatgggcatatgcataataattaataataagaacttccataagagcactgga
atgtcatctcgctctggtacggatgtggacgcagccaacctcagagagacattcatgggc
ctgaaataccaagtcaggaataaaaatgatcttactcgtgaagacattttggaattaatg
gatagtgtttctaaggaagatcatagcaaaaggagcagctttgtgtgtgtgattctaagc
catggtgatgaaggggtcatttatgggacaaatgggcctgttgaactgaaaaagttgact
agcttcttcagaggcgactactgccggagtctgactggaaagccgaaactcttcatcatt
caggcctgccggggtacggagctggactgtggcattgagacagacagtgggactgatgag
gagatggcttgccagaagataccggtggaggctgacttcctgtatgcttactctacagca
cctggttactattcctggagaaattcaaaggacgggtcgtggttcatccagtccctttgc
agcatgctgaagctgtacgcgcacaagctagaatttatgcacattctcactcgcgttaac
aggaaggtggcaacggaattcgagtccttctccctggactccactttccacgcaaagaaa
cagatcccgtgtattgtgtccatgctcacgaaagaactgtacttttatcactag

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