KEGG T01002: 18193

Mus musculus (mouse): 18193

Entry

18193 CDS T01002

Gene name

Nsd1, AI528500, KMT3B

Definition

nuclear receptor-binding SET-domain protein 1 (EC:2.1.1.43)

Orthology

K15588

histone-lysine N-methyltransferase NSD1 [EC:2.1.1.43]

Organism

mmu Mus musculus (mouse)

Pathway

mmu00310

Lysine degradation

Class

Metabolism; Amino acid metabolism; Lysine degradation [PATH:mmu00310]

SSDB

Motif

Pfam:

PWWP SET PHD PHD_2

Other DBs

NCBI-GI:

NCBI-GeneID:

MGI:

Ensembl:

UniProt:

Position

13 B1; 13

AA seq 2691 aa
MDRTCELSRRNCLLSFSNPVNLDASEDKDSPFGNGQSNFSEPLNGCTMQLPTAASGTSQN
AYGQDSPSCYIPLRRLQDLASMINVEYLSGSADGSESFQDPAKSDSRAQSPIVCTSLSPG
GPTALAMKQEPTCNNSPELQLRVTKTTKNGFLHFENFTGVDDADVDSEMDPEQPVTEDES
IEEIFEETQTNATCNYEPKSENGVEVAMGSEQDSMPESRHGAVERPFLPLAPQTEKQKNK
QRSEVDGSNEKTALLPAPTSLGDTNVTVEEQFNSINLSFQDDPDSSPSPLGNMLEIPGTS
SPSTSQELPFCQPKKKSTPLKYEVGDLIWAKFKRRPWWPCRICSDPLINTHSKMKVANRR
PYREYYVEAFGDPSEKAWVAGKAIVMFEGRHQFEELPVLRKRGKQKEKGYRHKVPQKILS
KWEASVGLAEQYDVPKGSKNQKCVSSSVKLDSEEDMPFEDCTNDPDSEHLLLNGCLKSLA
FDSEHSADEKEKPCAKSRVRKSSDNIKRTSVKKDLVPFESRKEERRGKIPDNLGLDFISG
GVSDKQASNELSRIANSLTGSSTAPGSFLFSSSVQNTAKTDFETPDCDSLSGLSESALIS
KHSGEKKKLQPGQVCSSKVQLCYVGAGDEEKRSNSVSVSTTSDDGCSDLDPTEHNSGFQN
SVLGITDAFDKTENALSVHKNETQYSRYPVTNRIKEKQKSLITNSHADHLMGSTKTMEPE
TAELSQVNLSDLKISSPIPKPQPEFRNDGLTTKFSAPPGIRNENPLTKGGLANQTLLPLK
CRQPKFRSIKCKHKESPAVAETSATSEDLSLKCCSSDTNGSPLANISKSGKGEGLKLLNN
MHEKTRDSSDIETAVVKHVLSELKELSYRSLSEDVSDSGTAKASKPLLFSSASSQNHIPI
EPDYKFSTLLMMLKDMHDSKTKEQRLMTAQNLASYRTPDRGDCSSGSPVGTSKVLVLGSS
TPNSEKPGDSTQDSVHQSPGGGDSALSGELSSSLSSLASDKRELPACGKIRSNCIPRRNC
GRAKPSSKLRETISAQMVKPSVNPKALKTERKRKFSRLPAVTLAANRLGNKESGSVNGPS
RGGAEDPGKEEPLQQMDLLRNEDTHFSDVHFDSKAKQSDPDKNLEKEPSFENRKGPELGS
EMNTENDELHGVNQVVPKKRWQRLNQRRPKPGKRANRFREKENSEGAFGVLLPADAVQKA
REDYLEQRAPPTSKPEDSAADPNHGSHSESVAPRLNVCEKSSVGMGDVEKETGIPSLMPQ
TKLPEPAIRSEKKRLRKPSKWLLEYTEEYDQIFAPKKKQKKVQEQVHKVSSRCEDESLLA
RCQPSAQNKQVDENSLISTKEEPPVLEREAPFLEGPLAQSDLGVTHAELPQLTLSVPVAP
EASPRPALESEELLVKTPGNYESKRQRKPTKKLLESNDLDPGFMPKKGDLGLSRKCFEAS
RSGNGIVESRATSHLKEFSGGTTKIFDKPRKRKRQRLVTARVHYKKVKKEDLTKDTPSSE
GELLIHRTAASPKEILEEGVEHDPGMSASKKLQVERGGGAALKENVCQNCEKLGELLLCE
AQCCGAFHLECLGLPEMPRGKFICNECHTGIHTCFVCKQSGEDVKRCLLPLCGKFYHEEC
VQKYPPTVTQNKGFRCPLHICITCHAANPANVSASKGRLMRCVRCPVAYHANDFCLAAGS
KILASNSIICPNHFTPRRGCRNHEHVNVSWCFVCSEGGSLLCCDSCPAAFHRECLNIDIP
EGNWYCNDCKAGKKPHYREIVWVKVGRYRWWPAEICHPRAVPSNIDKMRHDVGEFPVLFF
GSNDYLWTHQARVFPYMEGDVSSKDKMGKGVDGTYKKALQEAAARFEELKAQKELRQLQE
DRKNDKKPPPYKHIKVNRPIGRVQIFTADLSEIPRCNCKATDENPCGIDSECINRMLLYE
CHPTVCPAGVRCQNQCFSKRQYPDVEIFRTLQRGWGLRTKTDIKKGEFVNEYVGELIDEE
ECRARIRYAQEHDITNFYMLTLDKDRIIDAGPKGNYARFMNHCCQPNCETQKWSVNGDTR
VGLFALSDIKAGTELTFNYNLECLGNGKTVCKCGAPNCSGFLGVRPKNQPIVTEEKSRKF
KRKPHGKRRSQGEVTKEREDECFSCGDAGQLVSCKKPGCPKVYHADCLNLTKRPAGKWEC
PWHQCDVCGKEAASFCEMCPSSFCKQHREGMLFISKLDGRLSCTEHDPCGPNPLEPGEIR
EYVPPTATSPPSPGTQPKEQSSEMATQGPKKSDQPPTDATQLLPLSKKALTGSCQRPLLP
ERPPERTDSSSHLLDRIRDLAGSGTKSQSLVSSQRPQDRPPAKEGPRPQPPDRASPMTRP
SSSPSVSSLPLERPLRMTDSRLDKSIGAASPKSQAVEKTPASTGLRLSSPDRLLTTNSPK
PQISDRPPEKSHASLTQRLPPPEKVLSAVVQSLVAKEKALRPVDQNTQSKHRPAVVMDLI
DLTPRQKERAASPQEVTPQADEKTAMLESSSWPSSKGLGHIPRATEKISVSESLQPSGKV
AAPSEHPWQAVKSLTHARFLSPPSAKAFLYESATQASGRTPVGAEQTPGPPSPAPGLVKQ
VKQLSRGLTAKSGQSFRSLGKISASLPNEEKKLTTTEQSPWGLGKASPGAGLWPIVAGQT
LAQACWSAGGTQTLAQTCWSLGRGQDPKPENAIQALNQAPSSRKCADSEKK

NT seq 8076 nt +upstreamnt +downstreamnt
atggatcggacttgtgaattatctagaagaaattgtctgctgtccttttctaatccggtg
aatttagatgcctccgaagacaaggacagccctttcggtaatggtcaatccaatttttct
gagccacttaatgggtgtactatgcagttaccgactgctgccagtggaacatcccaaaat
gcttatggacaagattctccatcttgttacattccactgcggagactacaggatttggcc
tccatgatcaatgtagaatatttaagtgggtctgctgatggatcagaatcctttcaagac
cctgcaaaaagtgattcaagagctcagtcgccaattgtttgcacttccttgagtcctggt
ggtccaacagcacttgctatgaaacaggagcccacttgtaataactcccccgaactccag
ttaagagtaacaaagacgaccaagaatggctttctgcactttgagaattttactggtgtg
gacgatgcagatgtagattctgaaatggacccagaacagccagtcacagaggatgagagt
atagaggagatctttgaggagactcagaccaatgccacctgcaattatgagcctaaatca
gagaatggtgtagaagtggccatgggaagtgaacaagacagcatgccagagagtagacat
ggtgcagtggaacggccattcttgccgttagctcctcaaactgaaaaacagaaaaataaa
caaagaagtgaagtggacggaagcaatgaaaagacagccctcctcccagcccccacctca
ctaggagacacgaacgttaccgtagaagagcaatttaactcaataaatttatcttttcag
gatgatccagactccagtcccagtccattaggaaacatgctagaaatacctggaacttca
tcaccatccacttcacaggaattgccattttgtcaaccgaagaaaaagtctacaccactg
aaatatgaagttggagatcttatttgggcaaaattcaagagacgcccttggtggccctgc
aggatctgttctgatccattgattaatacacactcaaaaatgaaagttgccaataggagg
ccatatcgcgaatactacgtagaggcttttggagacccttctgaaaaagcctgggtggct
ggaaaagcaatcgtcatgtttgaaggcagacatcaatttgaagaactacctgtccttagg
aaaagagggaaacagaaagaaaaaggatataggcataaggttcctcagaagattttgagt
aaatgggaagccagcgttggtcttgccgagcaatatgatgttcccaaaggctctaagaac
caaaagtgtgtcagtagctcagtcaagttggacagtgaggaagatatgccatttgaggac
tgtacaaacgatcctgattcagaacacctgttgcttaatggctgcttgaagtctctggct
tttgattctgagcattctgcagatgaaaaggaaaagccctgtgccaagtctcgagttaga
aaaagctctgataatataaaaaggactagtgtgaaaaaggatctggtgccatttgaatca
cgtaaagaagaacggagggggaaaattccagacaaccttggcctagactttatctctggg
ggtgtatctgataaacaggcttctaatgaactttccaggatagcaaacagcctcacaggg
tctagcactgcaccaggaagtttcctcttttcttccagtgtacagaacactgctaagaca
gactttgagactccagattgcgattccttatcaggtttgtctgagagtgctttaatctct
aaacattctggagagaaaaagaaactccaaccaggccaggtctgcagctcaaaagtacag
ctctgctacgttggagctggtgatgaggaaaagcgaagcaattctgtcagtgtgagtacc
acttctgatgatggctgcagtgacctggatcctacagagcacaactcaggattccagaac
agtgtccttggaattacagatgcttttgataaaacagagaatgctttatcggtgcacaaa
aatgaaacacagtattctagatatcctgtcacaaacaggataaaagagaaacagaaatcc
ctcattactaattcccatgcagaccatttaatgggttctaccaagacaatggagcctgaa
actgctgagttgtctcaggtcaatctttctgatcttaaaattagtagtcctattcccaaa
ccccaaccagaatttaggaatgatggtctcactacaaaattcagcgcgccaccaggcatt
cgtaatgaaaatccactgacaaagggtgggcttgcaaatcaaactctattacctctgaaa
tgcagacagcccaagtttcgtagtataaaatgcaagcataaagaaagcccagctgttgca
gaaacctcagctacaagtgaggacctcagtttgaaatgctgttcttctgataccaatggc
tctcctttggccaatatatccaaaagtgggaaaggagaggggctaaaactactgaacaat
atgcatgagaaaaccagagattctagtgacatagaaacagcagtggtgaagcacgttctt
tcggaactgaaggagctctcgtacagatcattaagtgaagacgtaagtgattctggaacg
gcaaaggcatcaaagccattactgttttcttctgcttctagtcagaatcatataccaatt
gaaccagattacaagtttagcacattgctgatgatgctgaaggatatgcatgacagtaag
acaaaggagcagcggttaatgactgctcaaaatctggcttcctacaggactccagatcgt
ggggactgttcttctggtagccctgtagggacatcaaaagttttggtgttaggaagctcc
acacccaattctgaaaagcctggagatagcactcaggactcagttcaccagagtcctggt
gggggtgactctgccttgtctggagagttgtcttcttccctgtccagcttagcttctgac
aaaagagagctccctgcttgtggtaaaattcgctctaactgtatcccaaggcgcaactgt
ggccgagcaaagccatcatccaagttgagagaaaccatttcagcccagatggtaaaacct
tcagtaaacccaaaagccttaaagactgagcggaagagaaagttcagccgacttccagct
gtgacacttgctgctaacagactgggaaacaaagaaagtggatcagtgaatggcccatcc
aggggtggggctgaagatcctggtaaagaagagcctctgcaacaaatggaccttttaaga
aatgaagacacacatttttcagatgtacattttgatagcaaggctaaacaatcggaccct
gataaaaatcttgaaaaagaaccttcttttgagaacagaaaaggcccagagttgggctct
gaaatgaacactgagaatgatgaactccatggtgttaatcaggtggtgcctaaaaagcgg
tggcagcgattaaaccaaaggcgccctaagcccggaaagcgtgctaacagatttagggag
aaagaaaactcggagggtgcttttggagtcttacttcctgctgacgctgtgcagaaggcc
cgggaagactacttagaacaaagagctcctcctacaagtaaacctgaggactcagcagca
gatcccaatcatggcagccactctgaatcggttgcgcctcggctgaatgtttgtgagaag
tccagtgttggcatgggtgatgtagaaaaggagacaggaattcccagtttgatgccacag
accaagctccctgagccagctattcggtcagagaagaaacgcctcaggaagccgagcaag
tggcttctggaatatacagaagaatatgatcagatatttgctcctaagaaaaaacaaaag
aaggtacaggaacaagtgcataaggtaagttcgcgctgtgaagacgaaagccttcttgcc
cgatgtcaacctagtgctcagaacaagcaggtggatgagaattctttgatttcaactaaa
gaagagcctccagttcttgaacgagaggctccatttttggaagggccattggctcagtca
gatcttggagttacacatgctgagttgccacagctgaccttgtctgttcctgtggctcca
gaagcctctccgcggcctgcccttgagtctgaggaattgctcgttaagacaccaggaaat
tatgaaagtaagcgtcaaagaaaaccaactaagaaacttcttgaatctaatgatttagac
cctggatttatgcccaagaagggtgaccttggcctttctagaaagtgctttgaagccagt
cgctcgggaaatggtattgttgaatcacgggctacatctcatttgaaagagttcagtgga
ggcactaccaagatctttgataaaccaaggaaacggaaacggcagaggcttgtcacagcc
agagtgcactataaaaaagtgaagaaggaggacttaacaaaagacacacccagctcggag
ggagaactgctgattcacaggactgctgccagccccaaggagattcttgaagagggtgta
gaacatgatcctgggatgtctgcatccaagaaactgcaggttgaaagaggcggaggagcg
gcactcaaggagaatgtgtgtcagaactgtgagaagctgggtgagctgctgttgtgtgag
gctcagtgctgcggggctttccacttggagtgccttggcctccccgagatgcctcgaggg
aaatttatctgcaacgagtgtcacacaggaatccatacctgttttgtatgtaagcagagt
ggagaagatgtgaaaaggtgccttctacccttatgtgggaaattttaccatgaagagtgt
gtccagaagtacccaccgactgtcacacagaacaagggcttcaggtgccccctccacatt
tgtataacctgccatgctgctaatccagccaatgtatctgcttctaaaggtcgtctgatg
cgctgtgtccgctgtcctgtggcataccatgctaatgacttttgtcttgctgctggttca
aaaatccttgcatctaatagtatcatctgccctaatcacttcacccctaggcggggctgc
cgaaatcatgagcatgttaatgtcagctggtgttttgtgtgttcagaaggaggcagcctt
ctgtgctgtgattcttgccctgctgcttttcatcgagaatgcctaaatatcgatatccct
gaaggaaattggtactgcaatgactgtaaggcaggcaaaaagccacactacagggagatt
gtctgggtaaaagttggtcgctacaggtggtggccagctgagatctgccatcctcgagct
gttccctctaacattgataaaatgaggcacgatgtgggagaattccctgttctcttcttt
gggtccaatgactatctgtggactcatcaggctcgagtcttcccttacatggaaggggat
gtaagcagcaaggataagatgggaaaaggagttgatggaacatataaaaaagctcttcag
gaagctgcagcaagatttgaagagttaaaagctcaaaaagaattaagacagctgcaggaa
gatcggaagaatgacaagaagccgccaccttacaaacatataaaggtgaaccggcctatt
ggcagggtacagatcttcactgcagatttgtcagaaattccccgttgcaattgtaaagct
actgatgagaacccctgcgggatagactcagagtgtatcaaccggatgctgctctatgag
tgccacccaacagtgtgtcctgcaggagttcgctgtcagaaccagtgcttcagcaagcgc
cagtatccagatgttgaaattttccgcacattacaaaggggctggggtctccgaacaaaa
acggatattaaaaagggagaatttgtgaatgaatatgtgggtgagctaatagatgaagaa
gagtgcagagctcggatccgttacgcacaagagcacgacatcactaatttctatatgctc
acgctagataaagatcgaatcattgatgctggtcctaaagggaactacgcacgcttcatg
aatcactgctgccagcctaattgtgagacacagaagtggtcggtgaatggagatacccgt
gttggtctttttgctttgagtgacattaaagcaggcactgaacttaccttcaattacaac
ctagagtgtcttgggaatggaaaaaccgtctgtaaatgtggagcacccaactgcagtggc
ttcttgggtgtgaggccaaagaatcaacccattgtcacagaagaaaagtcaaggaaattc
aaaaggaagccacatgggaagcgcaggagccagggcgaagtcaccaaggaaagagaggat
gaatgtttcagctgtggggatgctggtcagctcgtctcctgcaagaagccaggctgccct
aaagtctaccatgcagactgtctgaatctgacaaagcgaccagcagggaagtgggaatgt
ccttggcaccagtgtgacgtgtgtgggaaggaagcagcctccttctgtgagatgtgcccc
agctccttttgcaagcaacatcgagaagggatgcttttcatttccaagctcgatgggcgt
ctgtcttgtactgaacatgatccctgtgggcccaaccctctggaacctggggagatccgt
gagtatgtgcctcccacagcgacgagtcctccaagccccggcactcagccaaaagagcag
tcatcagagatggctactcaggggcccaagaagtctgatcagccacctactgatgccacc
cagttgctgccactctccaaaaaagccctaacagggtcttgtcagaggccactgctccct
gaaaggcctcctgagagaactgactctagttcccaccttttagataggatcagagacctt
gctgggtcagggaccaaatcccagtccttggtatccagccagagaccacaggacaggcca
cctgctaaagaaggaccaagacctcagccacctgacagagcctctccaatgaccaggcca
agctcatcaccttcagtcagctccctgccactggaaagacctctaagaatgactgactcc
aggctggataaatccataggtgctgccagcccaaagtcccaggcagtggagaaaactcca
gcctccactggcctgagactttcatcaccagacaggctgctaaccactaacagtcccaaa
ccccagatttctgacaggcccccagagaagtcccatgcctctttgacccagagacttcca
cctcctgagaaagtgctatcagctgtggtccagtctctggtagctaaagagaaagccctg
aggcctgtggaccagaacacccaatcaaagcacagacctgctgtggtgatggatctcata
gacctaacgcctcgccagaaggagcgggctgcttctcctcaggaagtcaccccacaggct
gatgagaagacagcaatgctggagtcaagctcatggccgtccagcaaaggtctggggcat
atcccacgagctacggagaagatcagcgtgtcagagtccctccagccctcgggaaaagta
gcagctccttcagaacacccttggcaagctgttaaatcgctcacccatgccagatttctt
tctccgccttcggccaaggcttttttatatgaatcagcaactcaagcctcaggaagaacc
cctgtgggagctgagcagaccccaggacctcctagcccagcaccaggcctggttaaacag
gtgaaacagctatctagaggactcactgccaagagtgggcagtccttcaggtctcttggg
aagatctcagcttccctccccaatgaagaaaagaagttgacaaccacagaacagagtccc
tggggcctgggaaaagcctcaccaggggcagggctttggcctatagttgctggacaaaca
ctagcccaggcttgctggtctgctgggggcacacaaactttggcacaaacttgctggtct
cttggaagagggcaagaccccaaaccagaaaatgcaattcaagctcttaaccaggctcct
tctagtcgcaaatgtgcagattcagaaaagaaataa

All links

Pathway (1)   
   KEGG PATHWAY (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (5)   
   UniGene (2)   
   ENSEMBL-MMU (1)   
   MGI-MMU (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (2)   
   RefSeq(pep) (1)   
DNA sequence (63)   
   RefSeq(nuc) (1)   
   GenBank (31)   
   EMBL (31)   
Protein domain (4)   
   Pfam (4)   
All databases (94)   

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