KEGG   Mus musculus (house mouse): 18193
Entry
18193             CDS       T01002                                 
Symbol
Nsd1, KMT3B
Name
(RefSeq) nuclear receptor-binding SET-domain protein 1
  KO
K15588  [histone H3]-lysine36 N-dimethyltransferase NSD1 [EC:2.1.1.357]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00310  Lysine degradation
mmu01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    18193 (Nsd1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mmu03036]
    18193 (Nsd1)
Enzymes [BR:mmu01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.357  [histone H3]-lysine36 N-dimethyltransferase
     18193 (Nsd1)
Chromosome and associated proteins [BR:mmu03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     18193 (Nsd1)
SSDB
Motif
Pfam: PWWP SET C5HCH AWS PHD PHD_2 zf-HC5HC2H NGP1NT MUM1-like_PWWP
Other DBs
NCBI-GeneID: 18193
NCBI-ProteinID: NP_001395627
MGI: 1276545
Ensembl: ENSMUSG00000021488
Position
13:55357595..55466138
AA seq 2421 aa
MPPKTRTALSDDPDSSPSPLGNMLEIPGTSSPSTSQELPFCQPKKKSTPLKYEVGDLIWA
KFKRRPWWPCRICSDPLINTHSKMKVANRRPYREYYVEAFGDPSEKAWVAGKAIVMFEGR
HQFEELPVLRKRGKQKEKGYRHKVPQKILSKWEASVGLAEQYDVPKGSKNQKCVSSSVKL
DSEEDMPFEDCTNDPDSEHLLLNGCLKSLAFDSEHSADEKEKPCAKSRVRKSSDNIKRTS
VKKDLVPFESRKEERRGKIPDNLGLDFISGGVSDKQASNELSRIANSLTGSSTAPGSFLF
SSSVQNTAKTDFETPDCDSLSGLSESALISKHSGEKKKLQPGQVCSSKVQLCYVGAGDEE
KRSNSVSVSTTSDDGCSDLDPTEHNSGFQNSVLGITDAFDKTENALSVHKNETQYSRYPV
TNRIKEKQKSLITNSHADHLMGSTKTMEPETAELSQVNLSDLKISSPIPKPQPEFRNDGL
TTKFSAPPGIRNENPLTKGGLANQTLLPLKCRQPKFRSIKCKHKESPAVAETSATSEDLS
LKCCSSDTNGSPLANISKSGKGEGLKLLNNMHEKTRDSSDIETAVVKHVLSELKELSYRS
LSEDVSDSGTAKASKPLLFSSASSQNHIPIEPDYKFSTLLMMLKDMHDSKTKEQRLMTAQ
NLASYRTPDRGDCSSGSPVGTSKVLVLGSSTPNSEKPGDSTQDSVHQSPGGGDSALSGEL
SSSLSSLASDKRELPACGKIRSNCIPRRNCGRAKPSSKLRETISAQMVKPSVNPKALKTE
RKRKFSRLPAVTLAANRLGNKESGSVNGPSRGGAEDPGKEEPLQQMDLLRNEDTHFSDVH
FDSKAKQSDPDKNLEKEPSFENRKGPELGSEMNTENDELHGVNQVVPKKRWQRLNQRRPK
PGKRANRFREKENSEGAFGVLLPADAVQKAREDYLEQRAPPTSKPEDSAADPNHGSHSES
VAPRLNVCEKSSVGMGDVEKETGIPSLMPQTKLPEPAIRSEKKRLRKPSKWLLEYTEEYD
QIFAPKKKQKKVQEQVHKVSSRCEDESLLARCQPSAQNKQVDENSLISTKEEPPVLEREA
PFLEGPLAQSDLGVTHAELPQLTLSVPVAPEASPRPALESEELLVKTPGNYESKRQRKPT
KKLLESNDLDPGFMPKKGDLGLSRKCFEASRSGNGIVESRATSHLKEFSGGTTKIFDKPR
KRKRQRLVTARVHYKKVKKEDLTKDTPSSEGELLIHRTAASPKEILEEGVEHDPGMSASK
KLQVERGGGAALKENVCQNCEKLGELLLCEAQCCGAFHLECLGLPEMPRGKFICNECHTG
IHTCFVCKQSGEDVKRCLLPLCGKFYHEECVQKYPPTVTQNKGFRCPLHICITCHAANPA
NVSASKGRLMRCVRCPVAYHANDFCLAAGSKILASNSIICPNHFTPRRGCRNHEHVNVSW
CFVCSEGGSLLCCDSCPAAFHRECLNIDIPEGNWYCNDCKAGKKPHYREIVWVKVGRYRW
WPAEICHPRAVPSNIDKMRHDVGEFPVLFFGSNDYLWTHQARVFPYMEGDVSSKDKMGKG
VDGTYKKALQEAAARFEELKAQKELRQLQEDRKNDKKPPPYKHIKVNRPIGRVQIFTADL
SEIPRCNCKATDENPCGIDSECINRMLLYECHPTVCPAGVRCQNQCFSKRQYPDVEIFRT
LQRGWGLRTKTDIKKGEFVNEYVGELIDEEECRARIRYAQEHDITNFYMLTLDKDRIIDA
GPKGNYARFMNHCCQPNCETQKWSVNGDTRVGLFALSDIKAGTELTFNYNLECLGNGKTV
CKCGAPNCSGFLGVRPKNQPIVTEEKSRKFKRKPHGKRRSQGEVTKEREDECFSCGDAGQ
LVSCKKPGCPKVYHADCLNLTKRPAGKWECPWHQCDVCGKEAASFCEMCPSSFCKQHREG
MLFISKLDGRLSCTEHDPCGPNPLEPGEIREYVPPTATSPPSPGTQPKEQSSEMATQGPK
KSDQPPTDATQLLPLSKKALTGSCQRPLLPERPPERTDSSSHLLDRIRDLAGSGTKSQSL
VSSQRPQDRPPAKEGPRPQPPDRASPMTRPSSSPSVSSLPLERPLRMTDSRLDKSIGAAS
PKSQAVEKTPASTGLRLSSPDRLLTTNSPKPQISDRPPEKSHASLTQRLPPPEKVLSAVV
QSLVAKEKALRPVDQNTQSKHRPAVVMDLIDLTPRQKERAASPQEVTPQADEKTAMLESS
SWPSSKGLGHIPRATEKISVSESLQPSGKVAAPSEHPWQAVKSLTHARFLSPPSAKAFLY
ESATQASGRTPVGAEQTPGPPSPAPGLVKQVKQLSRGLTAKSGQSFRSLGKISASLPNEE
KKLTTTEQSPWGLGKASPGAGLWPIVAGQTLAQACWSAGGTQTLAQTCWSLGRGQDPKPE
NAIQALNQAPSSRKCADSEKK
NT seq 7266 nt   +upstreamnt  +downstreamnt
atgcctccgaagacaaggacagccctttcggatgatccagactccagtcccagtccatta
ggaaacatgctagaaatacctggaacttcatcaccatccacttcacaggaattgccattt
tgtcaaccgaagaaaaagtctacaccactgaaatatgaagttggagatcttatttgggca
aaattcaagagacgcccttggtggccctgcaggatctgttctgatccattgattaataca
cactcaaaaatgaaagttgccaataggaggccatatcgcgaatactacgtagaggctttt
ggagacccttctgaaaaagcctgggtggctggaaaagcaatcgtcatgtttgaaggcaga
catcaatttgaagaactacctgtccttaggaaaagagggaaacagaaagaaaaaggatat
aggcataaggttcctcagaagattttgagtaaatgggaagccagcgttggtcttgccgag
caatatgatgttcccaaaggctctaagaaccaaaagtgtgtcagtagctcagtcaagttg
gacagtgaggaagatatgccatttgaggactgtacaaacgatcctgattcagaacacctg
ttgcttaatggctgcttgaagtctctggcttttgattctgagcattctgcagatgaaaag
gaaaagccctgtgccaagtctcgagttagaaaaagctctgataatataaaaaggactagt
gtgaaaaaggatctggtgccatttgaatcacgtaaagaagaacggagggggaaaattcca
gacaaccttggcctagactttatctctgggggtgtatctgataaacaggcttctaatgaa
ctttccaggatagcaaacagcctcacagggtctagcactgcaccaggaagtttcctcttt
tcttccagtgtacagaacactgctaagacagactttgagactccagattgcgattcctta
tcaggtttgtctgagagtgctttaatctctaaacattctggagagaaaaagaaactccaa
ccaggccaggtctgcagctcaaaagtacagctctgctacgttggagctggtgatgaggaa
aagcgaagcaattctgtcagtgtgagtaccacttctgatgatggctgcagtgacctggat
cctacagagcacaactcaggattccagaacagtgtccttggaattacagatgcttttgat
aaaacagagaatgctttatcggtgcacaaaaatgaaacacagtattctagatatcctgtc
acaaacaggataaaagagaaacagaaatccctcattactaattcccatgcagaccattta
atgggttctaccaagacaatggagcctgaaactgctgagttgtctcaggtcaatctttct
gatcttaaaattagtagtcctattcccaaaccccaaccagaatttaggaatgatggtctc
actacaaaattcagcgcgccaccaggcattcgtaatgaaaatccactgacaaagggtggg
cttgcaaatcaaactctattacctctgaaatgcagacagcccaagtttcgtagtataaaa
tgcaagcataaagaaagcccagctgttgcagaaacctcagctacaagtgaggacctcagt
ttgaaatgctgttcttctgataccaatggctctcctttggccaatatatccaaaagtggg
aaaggagaggggctaaaactactgaacaatatgcatgagaaaaccagagattctagtgac
atagaaacagcagtggtgaagcacgttctttcggaactgaaggagctctcgtacagatca
ttaagtgaagacgtaagtgattctggaacggcaaaggcatcaaagccattactgttttct
tctgcttctagtcagaatcatataccaattgaaccagattacaagtttagcacattgctg
atgatgctgaaggatatgcatgacagtaagacaaaggagcagcggttaatgactgctcaa
aatctggcttcctacaggactccagatcgtggggactgttcttctggtagccctgtaggg
acatcaaaagttttggtgttaggaagctccacacccaattctgaaaagcctggagatagc
actcaggactcagttcaccagagtcctggtgggggtgactctgccttgtctggagagttg
tcttcttccctgtccagcttagcttctgacaaaagagagctccctgcttgtggtaaaatt
cgctctaactgtatcccaaggcgcaactgtggccgagcaaagccatcatccaagttgaga
gaaaccatttcagcccagatggtaaaaccttcagtaaacccaaaagccttaaagactgag
cggaagagaaagttcagccgacttccagctgtgacacttgctgctaacagactgggaaac
aaagaaagtggatcagtgaatggcccatccaggggtggggctgaagatcctggtaaagaa
gagcctctgcaacaaatggaccttttaagaaatgaagacacacatttttcagatgtacat
tttgatagcaaggctaaacaatcggaccctgataaaaatcttgaaaaagaaccttctttt
gagaacagaaaaggcccagagttgggctctgaaatgaacactgagaatgatgaactccat
ggtgttaatcaggtggtgcctaaaaagcggtggcagcgattaaaccaaaggcgccctaag
cccggaaagcgtgctaacagatttagggagaaagaaaactcggagggtgcttttggagtc
ttacttcctgctgacgctgtgcagaaggcccgggaagactacttagaacaaagagctcct
cctacaagtaaacctgaggactcagcagcagatcccaatcatggcagccactctgaatcg
gttgcgcctcggctgaatgtttgtgagaagtccagtgttggcatgggtgatgtagaaaag
gagacaggaattcccagtttgatgccacagaccaagctccctgagccagctattcggtca
gagaagaaacgcctcaggaagccgagcaagtggcttctggaatatacagaagaatatgat
cagatatttgctcctaagaaaaaacaaaagaaggtacaggaacaagtgcataaggtaagt
tcgcgctgtgaagacgaaagccttcttgcccgatgtcaacctagtgctcagaacaagcag
gtggatgagaattctttgatttcaactaaagaagagcctccagttcttgaacgagaggct
ccatttttggaagggccattggctcagtcagatcttggagttacacatgctgagttgcca
cagctgaccttgtctgttcctgtggctccagaagcctctccgcggcctgcccttgagtct
gaggaattgctcgttaagacaccaggaaattatgaaagtaagcgtcaaagaaaaccaact
aagaaacttcttgaatctaatgatttagaccctggatttatgcccaagaagggtgacctt
ggcctttctagaaagtgctttgaagccagtcgctcgggaaatggtattgttgaatcacgg
gctacatctcatttgaaagagttcagtggaggcactaccaagatctttgataaaccaagg
aaacggaaacggcagaggcttgtcacagccagagtgcactataaaaaagtgaagaaggag
gacttaacaaaagacacacccagctcggagggagaactgctgattcacaggactgctgcc
agccccaaggagattcttgaagagggtgtagaacatgatcctgggatgtctgcatccaag
aaactgcaggttgaaagaggcggaggagcggcactcaaggagaatgtgtgtcagaactgt
gagaagctgggtgagctgctgttgtgtgaggctcagtgctgcggggctttccacttggag
tgccttggcctccccgagatgcctcgagggaaatttatctgcaacgagtgtcacacagga
atccatacctgttttgtatgtaagcagagtggagaagatgtgaaaaggtgccttctaccc
ttatgtgggaaattttaccatgaagagtgtgtccagaagtacccaccgactgtcacacag
aacaagggcttcaggtgccccctccacatttgtataacctgccatgctgctaatccagcc
aatgtatctgcttctaaaggtcgtctgatgcgctgtgtccgctgtcctgtggcataccat
gctaatgacttttgtcttgctgctggttcaaaaatccttgcatctaatagtatcatctgc
cctaatcacttcacccctaggcggggctgccgaaatcatgagcatgttaatgtcagctgg
tgttttgtgtgttcagaaggaggcagccttctgtgctgtgattcttgccctgctgctttt
catcgagaatgcctaaatatcgatatccctgaaggaaattggtactgcaatgactgtaag
gcaggcaaaaagccacactacagggagattgtctgggtaaaagttggtcgctacaggtgg
tggccagctgagatctgccatcctcgagctgttccctctaacattgataaaatgaggcac
gatgtgggagaattccctgttctcttctttgggtccaatgactatctgtggactcatcag
gctcgagtcttcccttacatggaaggggatgtaagcagcaaggataagatgggaaaagga
gttgatggaacatataaaaaagctcttcaggaagctgcagcaagatttgaagagttaaaa
gctcaaaaagaattaagacagctgcaggaagatcggaagaatgacaagaagccgccacct
tacaaacatataaaggtgaaccggcctattggcagggtacagatcttcactgcagatttg
tcagaaattccccgttgcaattgtaaagctactgatgagaacccctgcgggatagactca
gagtgtatcaaccggatgctgctctatgagtgccacccaacagtgtgtcctgcaggagtt
cgctgtcagaaccagtgcttcagcaagcgccagtatccagatgttgaaattttccgcaca
ttacaaaggggctggggtctccgaacaaaaacggatattaaaaagggagaatttgtgaat
gaatatgtgggtgagctaatagatgaagaagagtgcagagctcggatccgttacgcacaa
gagcacgacatcactaatttctatatgctcacgctagataaagatcgaatcattgatgct
ggtcctaaagggaactacgcacgcttcatgaatcactgctgccagcctaattgtgagaca
cagaagtggtcggtgaatggagatacccgtgttggtctttttgctttgagtgacattaaa
gcaggcactgaacttaccttcaattacaacctagagtgtcttgggaatggaaaaaccgtc
tgtaaatgtggagcacccaactgcagtggcttcttgggtgtgaggccaaagaatcaaccc
attgtcacagaagaaaagtcaaggaaattcaaaaggaagccacatgggaagcgcaggagc
cagggcgaagtcaccaaggaaagagaggatgaatgtttcagctgtggggatgctggtcag
ctcgtctcctgcaagaagccaggctgccctaaagtctaccatgcagactgtctgaatctg
acaaagcgaccagcagggaagtgggaatgtccttggcaccagtgtgacgtgtgtgggaag
gaagcagcctccttctgtgagatgtgccccagctccttttgcaagcaacatcgagaaggg
atgcttttcatttccaagctcgatgggcgtctgtcttgtactgaacatgatccctgtggg
cccaaccctctggaacctggggagatccgtgagtatgtgcctcccacagcgacgagtcct
ccaagccccggcactcagccaaaagagcagtcatcagagatggctactcaggggcccaag
aagtctgatcagccacctactgatgccacccagttgctgccactctccaaaaaagcccta
acagggtcttgtcagaggccactgctccctgaaaggcctcctgagagaactgactctagt
tcccaccttttagataggatcagagaccttgctgggtcagggaccaaatcccagtccttg
gtatccagccagagaccacaggacaggccacctgctaaagaaggaccaagacctcagcca
cctgacagagcctctccaatgaccaggccaagctcatcaccttcagtcagctccctgcca
ctggaaagacctctaagaatgactgactccaggctggataaatccataggtgctgccagc
ccaaagtcccaggcagtggagaaaactccagcctccactggcctgagactttcatcacca
gacaggctgctaaccactaacagtcccaaaccccagatttctgacaggcccccagagaag
tcccatgcctctttgacccagagacttccacctcctgagaaagtgctatcagctgtggtc
cagtctctggtagctaaagagaaagccctgaggcctgtggaccagaacacccaatcaaag
cacagacctgctgtggtgatggatctcatagacctaacgcctcgccagaaggagcgggct
gcttctcctcaggaagtcaccccacaggctgatgagaagacagcaatgctggagtcaagc
tcatggccgtccagcaaaggtctggggcatatcccacgagctacggagaagatcagcgtg
tcagagtccctccagccctcgggaaaagtagcagctccttcagaacacccttggcaagct
gttaaatcgctcacccatgccagatttctttctccgccttcggccaaggcttttttatat
gaatcagcaactcaagcctcaggaagaacccctgtgggagctgagcagaccccaggacct
cctagcccagcaccaggcctggttaaacaggtgaaacagctatctagaggactcactgcc
aagagtgggcagtccttcaggtctcttgggaagatctcagcttccctccccaatgaagaa
aagaagttgacaaccacagaacagagtccctggggcctgggaaaagcctcaccaggggca
gggctttggcctatagttgctggacaaacactagcccaggcttgctggtctgctgggggc
acacaaactttggcacaaacttgctggtctcttggaagagggcaagaccccaaaccagaa
aatgcaattcaagctcttaaccaggctccttctagtcgcaaatgtgcagattcagaaaag
aaataa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (72)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (63)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (42)   
   RefSeq(pep) (42)   
DNA sequence (89)   
   RefSeq(nuc) (43)   
   GenBank (23)   
   EMBL (23)   
Protein domain (9)   
   Pfam (9)   
All databases (228)   

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