KEGG   Mus musculus (house mouse): 18550
Entry
18550             CDS       T01002                                 
Symbol
Furin, 9130404I01Rik, Fur, PACE, Pcsk3, SPC1
Name
(RefSeq) furin, paired basic amino acid cleaving enzyme
  KO
K01349  furin [EC:3.4.21.75]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu03250  Viral life cycle - HIV-1
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03250 Viral life cycle - HIV-1
    18550 (Furin)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:mmu01002]
    18550 (Furin)
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:mmu03110]
    18550 (Furin)
   04131 Membrane trafficking [BR:mmu04131]
    18550 (Furin)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.75  furin
     18550 (Furin)
Peptidases and inhibitors [BR:mmu01002]
 Serine peptidases
  Family S8: subtilisin family
   18550 (Furin)
Chaperones and folding catalysts [BR:mmu03110]
 Intramolecular chaperones
  Subtilisin family
   18550 (Furin)
Membrane trafficking [BR:mmu04131]
 Endosome - Golgi transport
  Others
   Others
    18550 (Furin)
SSDB
Motif
Pfam: Peptidase_S8 S8_pro-domain P_proprotein Furin-like_2 VSP DUF357
Other DBs
NCBI-GeneID: 18550
NCBI-ProteinID: NP_001074923
MGI: 97513
Ensembl: ENSMUSG00000030530
UniProt: P23188
Structure
Position
7:complement(80038942..80055188)
AA seq 793 aa
MELRSWLLWVVAAAGAVVLLAADAQGQKIFTNTWAVHIPGGPAVADRVAQKHGFHNLGQI
FGDYYHFWHRAVTKRSLSPHRPRHSRLQREPQVKWLEQQVAKRRAKRDVYQEPTDPKFPQ
QWYLSGVTQRDLNVKEAWAQGFTGHGIVVSILDDGIEKNHPDLAGNYDPGASFDVNDQDP
DPQPRYTQMNDNRHGTRCAGEVAAVANNGVCGVGVAYNARIGGVRMLDGEVTDAVEARSL
GLNPNHIHIYSASWGPEDDGKTVDGPARLAEEAFFRGVSQGRGGLGSIFVWASGNGGREH
DSCNCDGYTNSIYTLSISSATQFGNVPWYSEACSSTLATTYSSGNQNEKQIVTTDLRQKC
TESHTGTSASAPLAAGIIALTLEANKNLTWRDMQHLVVQTSKPAHLNADDWATNGVGRKV
SHSYGYGLLDAGAMVALAQNWTTVAPQRKCIVEILVEPKDIGKRLEVRKAVTACLGEPNH
ITRLEHVQARLTLSYNRRGDLAIHLISPMGTRSTLLAARPHDYSADGFNDWAFMTTHSWD
EDPAGEWVLEIENTSEANNYGTLTKFTLVLYGTAPEGLSTPPESSGCKTLTSSQACVVCE
EGYSLHQKSCVQHCPPGFIPQVLDTHYSTENDVEIIRASVCTPCHASCATCQGPAPTDCL
SCPSHASLDPVEQTCSRQSQSSRESRPQQQPPALRPEVEMEPRLQAGLASHLPEVLAGLS
CLIIVLIFGIVFLFLHRCSGFSFRGVKVYTMDRGLISYKGLPPEAWQEECPSDSEEDEGR
GERTAFIKDQSAL
NT seq 2382 nt   +upstreamnt  +downstreamnt
atggagctgagatcctggttgctatgggtggtcgcagcagcaggagccgtggtcctgctg
gcagctgatgctcaaggccagaagatcttcaccaacacctgggccgtgcacattcctgga
ggcccagctgtggctgatagggtggcgcagaagcatggcttccacaacctgggccagatc
ttcggtgactattaccacttctggcacagagcagtgacaaagcggtccctgtcgcctcac
cgcccgcggcacagccggctacagagggagcctcaagtaaagtggctggagcagcaggta
gccaagcgaagagccaagagggacgtgtatcaggagcccacggaccccaagttcccccag
cagtggtacctgtctggtgtcactcagcgagacctgaatgtgaaggaggcctgggcccag
ggcttcacaggccatggcattgtggtctccatcctggatgacggcattgagaagaatcat
cccgacctagcaggcaattatgaccctggagccagttttgacgtgaatgaccaggacccc
gacccacagcctcggtacacacagatgaatgacaacaggcatggcactcgctgtgccggg
gaagtggcagcagtggccaacaatggtgtctgtggcgtaggtgtagcttacaatgcccga
attggaggggtgcggatgttggatggcgaggtgactgatgcagtagaggcacgttcgctg
ggcctgaatcccaaccacatccacatctacagcgccagctggggccctgaggacgacggc
aagaccgtggatggaccagcccggctcgctgaggaggccttctttcggggagttagccag
ggccgaggagggctgggctccatctttgtctgggcctcagggaatgggggccgggaacat
gacagctgcaactgtgacggctacaccaacagcatctatacactgtccatcagcagcgcc
acacagttcggcaatgtgccctggtacagtgaggcctgctcctccacactggccaccacc
tacagcagcggcaaccagaatgagaagcagatcgtgacaactgacctgaggcagaagtgc
acagaatctcacacaggcacctcggcttctgcccccttggcagctggtatcattgctctc
accctggaggccaacaagaacctcacctggcgggacatgcagcacctggtagtgcagacc
tcaaagccagcccacctcaacgctgatgattgggctaccaacggcgtgggccggaaagtg
agccattcgtatggctacgggctgttggatgcaggtgccatggtggctctggcccagaac
tggacaacagtggccccccagcggaagtgcattgttgaaatcctggtggaacccaaggac
atcggcaaacggctagaggtgcgcaaggcggtgacagcatgcctgggtgagcccaaccac
atcaccaggctggaacacgttcaggcccggctcaccctgtcttacaatcgccgcggtgac
ctggctatccacctcatcagccccatgggcacccgctccaccctgttagctgccagacca
catgactactctgctgatgggtttaatgattgggctttcatgacaacccattcctgggat
gaggatccggctggcgaatgggtcctagagattgaaaataccagtgaagccaacaactat
gggacgctgaccaagttcactctcgttctgtatggcacagcccccgaggggctctctaca
cctccagaaagcagcggctgcaagaccctcacatccagccaggcctgcgtggtgtgtgag
gaaggttactctctgcaccagaaaagctgtgtccagcactgcccaccaggcttcatcccc
caagtccttgatacacactacagcactgagaatgatgtggagatcatccgtgccagcgtc
tgtaccccctgccacgcctcatgtgccacttgccagggcccggcccccacagactgcctc
agctgccccagccatgcctccctggacccagtggagcagacctgctcccggcaaagccag
agcagccgggagtctcggcctcagcagcagcctcctgcactgcgccctgaggtggagatg
gagccccggctgcaggctgggttggcctctcacctgcccgaggtcctggccggcctcagc
tgccttatcatcgtgctcatctttggcatcgtcttcctgttcctgcatcggtgttcgggc
ttcagcttccggggagtgaaagtgtacaccatggaccgcggcctcatctcctacaagggg
ctgccccctgaagcctggcaggaggagtgcccatcggactcagaggaggacgagggccgg
ggcgagaggaccgccttcatcaaagaccagagcgccctttga

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Ontology (5)   
   KEGG BRITE (5)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (12)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (10)   
DNA sequence (26)   
   RefSeq(nuc) (10)   
   GenBank (8)   
   EMBL (8)   
3D Structure (1)   
   PDB (1)   
Protein domain (6)   
   Pfam (6)   
All databases (74)   

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