KEGG   Mus musculus (house mouse): 18754
Entry
18754             CDS       T01002                                 
Symbol
Prkce, 5830406C15Rik, PKC[e], PKCepsilon, Pkce
Name
(RefSeq) protein kinase C, epsilon
  KO
K18050  novel protein kinase C epsilon type [EC:2.7.11.13]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04022  cGMP-PKG signaling pathway
mmu04071  Sphingolipid signaling pathway
mmu04270  Vascular smooth muscle contraction
mmu04371  Apelin signaling pathway
mmu04530  Tight junction
mmu04666  Fc gamma R-mediated phagocytosis
mmu04750  Inflammatory mediator regulation of TRP channels
mmu04925  Aldosterone synthesis and secretion
mmu04930  Type II diabetes mellitus
mmu04931  Insulin resistance
mmu04933  AGE-RAGE signaling pathway in diabetic complications
mmu05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    18754 (Prkce)
   04071 Sphingolipid signaling pathway
    18754 (Prkce)
   04022 cGMP-PKG signaling pathway
    18754 (Prkce)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    18754 (Prkce)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    18754 (Prkce)
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    18754 (Prkce)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    18754 (Prkce)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    18754 (Prkce)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    18754 (Prkce)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    18754 (Prkce)
   04931 Insulin resistance
    18754 (Prkce)
   04933 AGE-RAGE signaling pathway in diabetic complications
    18754 (Prkce)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mmu01001]
    18754 (Prkce)
Enzymes [BR:mmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     18754 (Prkce)
Protein kinases [BR:mmu01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   18754 (Prkce)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C ABC1 PKC_C2 FTA2 Kinase-like Kdo PP_M1
Other DBs
NCBI-GeneID: 18754
NCBI-ProteinID: NP_035234
MGI: 97599
Ensembl: ENSMUSG00000045038
UniProt: P16054
Position
17:86472631..86965347
AA seq 737 aa
MVVFNGLLKIKICEAVSLKPTAWSLRHAVGPRPQTFLLDPYIALNVDDSRIGQTATKQKT
NSPAWHDEFVTDVCNGRKIELAVFHDAPIGYDDFVANCTIQFEELLQNGSRHFEDWIDLE
PEGKVYVIIDLSGSSGEAPKDNEERVFRERMRPRKRQGAVRRRVHQVNGHKFMATYLRQP
TYCSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHELIITKCAGLKKQETPDEVGSQRFSVN
MPHKFGIHNYKVPTFCDHCGSLLWGLLRQGLQCKVCKMNVHRRCETNVAPNCGVDARGIA
KVLADLGVTPDKITNSGQRRKKLAAGAESPQPASGNSPSEDDRSKSAPTSPCDQELKELE
NNIRKALSFDNRGEEHRASSATDGQLASPGENGEVRPGQAKRLGLDEFNFIKVLGKGSFG
KVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARKHPYLTQLYCCFQTKD
RLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILL
DAEGHCKLADFGMCKEGIMNGVTTTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEM
MAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKNPHKRLGCVAAQNGED
AIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKRDVNNFDQDFTREEPILTLVDEAIIKQI
NQEEFKGFSYFGEDLMP
NT seq 2214 nt   +upstreamnt  +downstreamnt
atggtagtgttcaatggccttcttaagatcaaaatctgcgaggcggtgagcttgaagccc
acagcctggtcgctgcgccatgcggtgggaccccggccacagacgttccttttggacccc
tacattgcccttaacgtggacgactcgcgcatcggccaaacagccaccaagcaaaagacc
aacagcccggcctggcacgatgagttcgtcaccgatgtgtgcaatgggcgcaagatcgag
ctggctgtctttcacgacgctcctatcggctacgacgacttcgtggccaactgcaccatc
cagttcgaggagctgctgcagaatgggagccgtcacttcgaggactggattgacctggag
ccagaaggaaaagtgtacgtgatcatcgatctctcgggatcatcgggtgaagcccctaaa
gacaatgaagaacgagtgttcagggagcgtatgcggccaaggaagcggcaaggggctgtc
aggcgcagggtccaccaggtcaatggccacaagttcatggccacctacttgcggcaaccc
acctactgctcccactgcagagatttcatctggggtgtcataggaaaacagggatatcaa
tgtcaagtttgcacttgcgttgtccacaagcgatgtcatgagctcattattacaaagtgc
gctgggctgaagaaacaggaaacccctgacgaggtgggctcccaacggttcagcgtcaac
atgccccacaagttcgggatccacaactacaaggtccccacgttctgtgaccactgtggg
tccctgctctggggcctcttgcggcagggcttgcagtgtaaagtctgcaaaatgaatgtt
caccggcgatgtgagaccaatgtggctcccaactgtggggtagacgccagaggaattgcc
aaagtgctggctgaccttggtgttactccagacaaaatcaccaacagtggccaaaggagg
aaaaagctcgctgctggtgctgagtccccacagccggcttctggaaactccccatctgaa
gacgaccgatccaagtcagcgcccacctccccttgtgaccaggaactaaaagaacttgaa
aacaacattcggaaggccttgtcatttgacaaccgaggagaggagcaccgagcgtcgtcg
gccaccgatggccagctggcaagccccggagagaacggggaagtccggccaggccaggcc
aagcgcttggggctggatgagttcaacttcatcaaggtgttgggcaaaggcagctttggc
aaggtcatgttggcggaactcaaaggcaaagatgaagtctacgctgtgaaggtcttgaag
aaggacgttatcctacaagacgatgatgtggactgcacaatgacagagaagaggattttg
gctctggctcggaaacacccttatctaacccaactctattgctgcttccagaccaaggac
cgcctcttcttcgtcatggaatatgtaaatggtggagacctcatgttccagattcagcgg
tcccgaaaatttgatgagcctcgttctcggttctatgccgcagaggtcacatcagccctc
atgtttctccaccagcacggagtgatctacagggatttgaaactggacaacatccttcta
gatgcagaaggccactgcaagctggctgactttgggatgtgcaaggaagggattatgaat
ggtgtgacaactaccaccttctgtgggactcctgactacatagctccagagatcctacag
gagttggagtacggcccctcagtggactggtgggccctgggggtgctgatgtacgagatg
atggctgggcagcccccctttgaagctgacaacgaggacgacttgttcgaatccatcctt
catgatgatgttctctatcctgtctggcttagcaaggaagctgtcagcatcctgaaagct
ttcatgaccaagaacccgcacaagcgcctgggctgtgtggcagcgcagaacggggaggac
gccatcaagcaacatccattcttcaaggagattgactgggtactgctggagcagaagaaa
atcaagccccccttcaagccgagaattaaaaccaaaagagatgtcaataactttgaccaa
gactttacgcgggaagagccaatacttacacttgtggatgaagcaatcattaagcagatc
aaccaggaagaattcaaaggcttctcctactttggtgaagacctgatgccctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (12)   
   KEGG PATHWAY (12)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (18)   
   RefSeq(nuc) (4)   
   GenBank (7)   
   EMBL (7)   
Protein domain (11)   
   Pfam (11)   
All databases (64)   

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