KEGG   Mus musculus (mouse): 18797Help
Entry
18797             CDS       T01002                                 

Gene name
Plcb3, mKIAA4098
Definition
phospholipase C, beta 3 (EC:3.1.4.11)
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
mmu  Mus musculus (mouse)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Class
Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:mmu00562]
Environmental Information Processing; Signal transduction; Rap1 signaling pathway [PATH:mmu04015]
Environmental Information Processing; Signal transduction; Wnt signaling pathway [PATH:mmu04310]
Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:mmu04020]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:mmu04070]
Cellular Processes; Cell communication; Gap junction [PATH:mmu04540]
Organismal Systems; Immune system; Chemokine signaling pathway [PATH:mmu04062]
Organismal Systems; Endocrine system; Insulin secretion [PATH:mmu04911]
Organismal Systems; Endocrine system; GnRH signaling pathway [PATH:mmu04912]
Organismal Systems; Endocrine system; Estrogen signaling pathway [PATH:mmu04915]
Organismal Systems; Endocrine system; Oxytocin signaling pathway [PATH:mmu04921]
Organismal Systems; Endocrine system; Thyroid hormone synthesis [PATH:mmu04918]
Organismal Systems; Endocrine system; Thyroid hormone signaling pathway [PATH:mmu04919]
Organismal Systems; Endocrine system; Melanogenesis [PATH:mmu04916]
Organismal Systems; Circulatory system; Adrenergic signaling in cardiomyocytes [PATH:mmu04261]
Organismal Systems; Circulatory system; Vascular smooth muscle contraction [PATH:mmu04270]
Organismal Systems; Digestive system; Salivary secretion [PATH:mmu04970]
Organismal Systems; Digestive system; Gastric acid secretion [PATH:mmu04971]
Organismal Systems; Digestive system; Pancreatic secretion [PATH:mmu04972]
Organismal Systems; Excretory system; Endocrine and other factor-regulated calcium reabsorption [PATH:mmu04961]
Organismal Systems; Nervous system; Glutamatergic synapse [PATH:mmu04724]
Organismal Systems; Nervous system; Cholinergic synapse [PATH:mmu04725]
Organismal Systems; Nervous system; Dopaminergic synapse [PATH:mmu04728]
Organismal Systems; Nervous system; Serotonergic synapse [PATH:mmu04726]
Organismal Systems; Nervous system; Long-term potentiation [PATH:mmu04720]
Organismal Systems; Nervous system; Long-term depression [PATH:mmu04730]
Organismal Systems; Nervous system; Retrograde endocannabinoid signaling [PATH:mmu04723]
Organismal Systems; Sensory system; Inflammatory mediator regulation of TRP channels [PATH:mmu04750]
Organismal Systems; Environmental adaptation; Circadian entrainment [PATH:mmu04713]
Human Diseases; Neurodegenerative diseases; Alzheimer's disease [PATH:mmu05010]
Human Diseases; Neurodegenerative diseases; Huntington's disease [PATH:mmu05016]
Human Diseases; Infectious diseases; Amoebiasis [PATH:mmu05146]
Human Diseases; Infectious diseases; Chagas disease (American trypanosomiasis) [PATH:mmu05142]
Human Diseases; Infectious diseases; African trypanosomiasis [PATH:mmu05143]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
MGI: 
Ensembl: 
UniProt: 
Position
19 B; 19 5.1 cM
AA seq 1234 aa AA seqDB search
MAGARPGVHALQLEPPTVVETLRRGSKFIKWDEEASSRNLVTLRVDPNGFFLYWTGPNME
VDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDTRLEEKLMTVVAGPDPVNTTFLNF
MAVQDDTVKVWSEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNILKMFS
ADKKRVETALESCGLNFNRVESIRPDEFPLEIFERFLNKLCLRPDIDKILLEIGAKGKPY
LTLEQLMDFINQKQRDPRLNEVLYPPLRSSQARLLIEKYETNKQFLERDQMSMEGFSRYL
GGEENGILPLEALDLSMDMTQPLSAYFINSSHNTYLTAGQLAGPSSVEMYRQALLWGCRC
VELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAEAAFKTSPYPVILSFENHVDSAK
QQAKMAEYCRSIFGDALLIDPLDKYPLSAGIPLPSPQDLMGRILVKNKKRHRPSTGVPDS
SVRKRPLEQSNSALSESSAATEPSSPQLGSPSSDSCPGLSNGEEVGLEKTSLEPQKSLGE
ESLSREPNVPMPDRDREDEEEDEEEEETTDPKKPTTDEGTASSEVNATEEMSTLVNYVEP
VKFKSFEAARKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQQLSRIYPKGTRVDSSNY
MPQLFWNVGCQLVALNFQTLDLPMQLNAGVFEYNGRSGYLLKPEFMRRPDKSFDPFTEVI
VDGIVANALRVKVISGQFLSDKKVGIYVEVDMFGLPVDTRRKYRTRTSQGNSFNPVWDEE
PFDFPKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHYVCLRNEANQPLCLPALL
IYTEASDYIPDDHQDYAEALINPIKHVSLMDQRAKQLAALIGESEAQASTETYQETPCQQ
PGSQLPSNPTPNPLDASPRWPPGPTTSSTSSSLSSPGQRDDLIASILSEVTPTPLEELRS
HKAMVKLRSRQDRDLRELHKKHQRKAVALTRRLLDGLAQARAEGKCRPSPSALGKATNSE
DVKEEEEAKQYREFQNRQVQSLLELREAQADVETKRKLEHLRQAHQRLKEVVLDTHTTQF
KRLKELNEREKKELQKILDRKRNNSISEAKTREKHKKEVELTEINRRHITESVNSIRRLE
EAQKQRHERLVAGQQQVLQQLEEEEPKLLAQLTQECQEQRERLPQEIRRCLLGETAEGLG
DGPLVACASNGHAPGSGGHLSSADSESQEENTQL
NT seq 3705 nt NT seq  +upstreamnt  +downstreamnt
atggcgggcgcgaggcccggcgtccacgcgctgcagctggagccgcccaccgtggtggag
accctgcggcgcgggagtaagttcatcaaatgggacgaggaggcctccagtcggaacctg
gtgaccctgcgtgtggaccctaatggcttcttcttgtactggacaggacccaacatggag
gtggacacactggacatcagctccatcagggacacaaggacaggtcgttatgcccgcctg
cccaaggaccctaagattcgagaagtactgggctttggaggtcctgacacccggctggag
gagaaactgatgacagtggtggccgggccagatccagtaaataccacattcttgaacttc
atggccgtgcaagatgacacagtcaaggtctggtcagaggagttgtttaaactggccatg
aacatattggctcagaacgcctcccggaacaccttcctgcggaaagcatacacgaagctg
aagctgcaggtgaaccaggatggacggattccggtcaagaacattctgaagatgttctcg
gcggacaagaagcgggtggagacggcgctggagtcctgtggcctcaacttcaaccgagtt
gagtccattcgccctgatgagtttcccttggaaatttttgagcggttcttgaataaactg
tgtctgcgcccggatattgacaagatcctgctggagataggtgccaagggcaagccgtac
ctcactctggagcagctcatggactttatcaaccagaagcagagagacccgagactcaac
gaagtgctgtacccgccacttcggtcctcacaggctcggctgctcattgagaagtacgag
acgaacaaacagttcctggagcgcgaccagatgtctatggagggcttcagccgctacctg
ggaggggaggagaatggtatcctgcctctggaggccctggatctgagcatggacatgacc
cagccactgagcgcatattttatcaactcctcacacaacacctatctcactgcgggccag
ctggctggaccatcatcggtggagatgtaccgccaggcactgctgtggggctgccgctgt
gtggagctggatgtatggaagggacggccaccggaggaagagcctttcatcactcatggt
ttcaccatgaccactgaggtgccattgcgtgatgtgctagaggccatcgctgaggcagcc
ttcaagacctcgccctaccctgtcatcctctcctttgagaaccatgtcgactcggcaaag
cagcaggccaagatggctgagtactgccgctctatctttggggatgcgctgctcattgac
cctctcgacaaatacccgctatctgcgggcatccccctgcctagtccacaggacctgatg
ggccgtatcctggtgaagaataagaagcgacatcggcccagcacaggtgtccctgacagc
tcagtgcgcaagcggcctctggaacagagcaactcggccttgagtgagagctcggccgcc
acagagccctcctcacctcagcttgggtcccccagctccgacagctgccctggcctaagc
aatggggaggaggtgggactcgagaagaccagcctggagcctcagaagtctctaggtgag
gagagcctcagccgggaacctaatgtgcccatgcctgaccgtgaccgagaggatgaggag
gaagatgaagaagaagaggaaacaacggatccaaaaaagcccaccactgatgagggcaca
gccagcagtgaggtcaatgccacggaggagatgtcaacgctcgtcaactacgttgagccc
gtcaagttcaagtccttcgaggctgctcgaaaaaggaacaagtgcttcgagatgtcatcc
ttcgtggagaccaaggcaatggagcaactgaccaagagtcctatggagtttgtggaatac
aacaaacagcagctcagccgcatctaccctaagggcacacgagtggactcctccaactac
atgcctcagctcttctggaacgtgggttgccagcttgttgccctcaacttccagaccttg
gatttgccaatgcagctcaacgcaggcgtgtttgagtacaatgggcgcagcgggtacttg
ctcaagcccgagtttatgcggcggccggacaagtcttttgatcccttcactgaggtcatc
gtagatggcatagtggccaacgccttgcgggtcaaggtgatttcggggcagttcctgtct
gacaagaaggtgggcatctacgtcgaggtggacatgtttggcctcccagttgacacaaga
cgcaaatatcgtacccggacatcccaggggaactcattcaaccctgtgtgggacgaggaa
ccctttgacttccccaaggttgtgctgcccacgctggcctcacttcgcatcgcagccttt
gaggagggtggcaaatttgttgggcaccgtatcctgcctgtctctgctatccgctcagga
taccactatgtctgcctgcgaaacgaggccaaccaacctttgtgcctgcctgccctgctt
atctacactgaagcttctgactacatcccagatgaccaccaggactatgcggaggccttg
attaaccccatcaagcacgtaagcctaatggaccagcgggccaagcaactagccgctctc
attggggagagtgaggctcaggccagcacagagacatatcaggagaccccgtgtcaacag
ccagggtcacagctcccctccaaccccacacctaacccactggatgcctcacctcgctgg
ccccccggtcctaccacttcctccactagctcctccctcagtagcccagggcagcgagat
gatttgattgccagcatcctctctgaggtgacccctacacctctagaggagctcagaagc
cacaaggctatggtgaagctacggagccggcaggatcgagacctgcgggagttgcataag
aagcaccagcgcaaggctgtggccctcacccgccgccttctggatggcctggcccaggcc
agggctgaggggaagtgccggccctcccccagtgccctgggcaaggccaccaactcggag
gacgtgaaggaggaagaggaggccaaacagtatcgagagttccagaaccgacaagtacag
agcctgttggagctgagggaagcccaggcagatgtggagaccaagcggaagctggagcat
ctacgacaggctcatcagcggctcaaggaggttgtcctggatacacacacaacacagttc
aagaggctgaaggagctgaatgaaagggagaagaaggaactccagaagatcctggacagg
aagcgcaacaacagcatctcagaggccaagacaagggagaaacacaagaaggaggtggaa
ctgacagagattaatcggcggcacatcactgagtcggtaaactccatcagacggctggaa
gaggcccagaagcagcgccatgaacgcctggtggcagggcaacagcaagtcctccagcag
ctagaggaagaggaacccaagctgctggcccagctgacccaggagtgtcaggaacagcga
gagaggttgccccaggagatccgtcggtgcctgctgggcgagacagcagagggactgggg
gacggccccctggtggcctgtgccagcaatggtcatgcacctgggagtggtgggcacctg
tccagcgctgactcggagagccaggaggagaacacccagctttga

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