KEGG   Mus musculus (mouse): 234779Help
Entry
234779            CDS       T01002                                 

Gene name
Plcg2, PLCgamma2, Plcg-2
Definition
phospholipase C, gamma 2 (EC:3.1.4.11)
Orthology
K05859  
phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11]
Organism
mmu  Mus musculus (mouse)
Pathway
Inositol phosphate metabolism
Metabolic pathways
ErbB signaling pathway
Ras signaling pathway
Calcium signaling pathway
NF-kappa B signaling pathway
HIF-1 signaling pathway
Phosphatidylinositol signaling system
VEGF signaling pathway
Osteoclast differentiation
Natural killer cell mediated cytotoxicity
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Inflammatory mediator regulation of TRP channels
Thyroid hormone signaling pathway
Epstein-Barr virus infection
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Glioma
Non-small cell lung cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Class
Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:mmu00562]
Environmental Information Processing; Signal transduction; Ras signaling pathway [PATH:mmu04014]
Environmental Information Processing; Signal transduction; ErbB signaling pathway [PATH:mmu04012]
Environmental Information Processing; Signal transduction; VEGF signaling pathway [PATH:mmu04370]
Environmental Information Processing; Signal transduction; NF-kappa B signaling pathway [PATH:mmu04064]
Environmental Information Processing; Signal transduction; HIF-1 signaling pathway [PATH:mmu04066]
Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:mmu04020]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:mmu04070]
Organismal Systems; Immune system; Natural killer cell mediated cytotoxicity [PATH:mmu04650]
Organismal Systems; Immune system; B cell receptor signaling pathway [PATH:mmu04662]
Organismal Systems; Immune system; Fc epsilon RI signaling pathway [PATH:mmu04664]
Organismal Systems; Immune system; Fc gamma R-mediated phagocytosis [PATH:mmu04666]
Organismal Systems; Immune system; Leukocyte transendothelial migration [PATH:mmu04670]
Organismal Systems; Endocrine system; Thyroid hormone signaling pathway [PATH:mmu04919]
Organismal Systems; Nervous system; Neurotrophin signaling pathway [PATH:mmu04722]
Organismal Systems; Sensory system; Inflammatory mediator regulation of TRP channels [PATH:mmu04750]
Organismal Systems; Development; Osteoclast differentiation [PATH:mmu04380]
Human Diseases; Cancers; Pathways in cancer [PATH:mmu05200]
Human Diseases; Cancers; MicroRNAs in cancer [PATH:mmu05206]
Human Diseases; Cancers; Proteoglycans in cancer [PATH:mmu05205]
Human Diseases; Cancers; Glioma [PATH:mmu05214]
Human Diseases; Cancers; Non-small cell lung cancer [PATH:mmu05223]
Human Diseases; Infectious diseases; Epstein-Barr virus infection [PATH:mmu05169]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
MGI: 
Ensembl: 
UniProt: 
Structure
PDB: 

Jmol
Position
8 E1; 8 64.26 cM
AA seq 1265 aa AA seqDB search
MTTMVNVDTLPEYEKSQIKRALELGTVMTVFNARKSTPERRTVQMIMETRQVAWSKTADK
IEGFLDIMEIKEIRPGKNSKDFERAKAVRHKAECCFTILYGTQFVLSTLSLATDSKEDAV
KWLSGLKILHQEAMSASTPTMIESWLRKQIYSVDQTRRNSISLRELKTILPLVNFKVSGI
KFLKDKLVEIGAQKDELSFEQFHLFYKKLMFDQQKSILDEFKKDSSVFILGNTDRPDASA
VYLQDFQRFLLHEQQELWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENS
IWDEKYDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRAGCRCIELDC
WDGPDGKPIIYHGWTRTTKIKFDDVVQAIRDHAFVTSSFPVILSIEEHCSVEQQRHMAKV
FKEVLGDMLLTKPTEASADQLPSPSQLREKIIIKHKKLGPKGDVDVNVEDKKDEHKPQGE
LYMWDSIDQKWTRHYCAIADAKLSFGDDIEQAVEEEPVQDTPPTELHFGEKWFHKKVESR
TSAEKLLQEYCAETGAKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMENGVMKYY
LTDNLTFNSIYALIQHYREAHLRCAEFELRLTDPVPNPNPHESKPWYYDSLSRGEAEDML
MRIPRDGAFLIRKREGTNSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYY
EKHALYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDY
KAKRSDELTFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISAGDAEEMEKQII
EDNPLGSLCKGILDLNTYNVVKAPQGKNQKAFVFILEPKKQGDPPVEFATDRVEELFEWF
QSIREITWKMDTKENNMKYWERNQSIAIELSDLVVYCKPTSKTKDHLENPDFREIRSFVE
TKADSIVRQKPVDLLRYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTPDKY
MQMNHALFSLNGRTGYVLQPESMRSEKYDPMPLESQRKILMTLTVKVLGARHLPKLGRSI
ACPFVEVEICGAEYDSNKFKTTVVNDNGLSPVWAPTQEKVTFEIYDPNLAFLRFVVYEED
MFSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSC
RQLRRRQEELNNQLFLYDTHQNLRGANRDALVKEFNVNENQLQLYQEKCNRRLREKRVSN
SRFYS
NT seq 3798 nt NT seq  +upstreamnt  +downstreamnt
atgaccaccatggtcaacgtggacacccttccagaatatgagaagagtcagatcaagaga
gcgctggagttagggacggtgatgaccgtgttcaacgcccgcaaatccaccccagagcgg
aggacagtacagatgatcatggagactcggcaggtggcatggagcaagaccgcagacaag
attgaaggcttcctggacatcatggagataaaggaaatccgtccggggaagaactccaag
gactttgagcgagccaaggctgtccgccacaaggcagaatgttgcttcaccatcctctac
ggcacccagtttgtcctcagcacgctcagtttggcaacggactcaaaggaggatgcggtg
aagtggctctctggtttgaagatcctacaccaggaagcgatgagtgcatccacccccaca
atgattgagagttggctgagaaaacagatttattcagtagatcaaacccgaagaaacagc
atcagcctccgggagctgaagaccatcttgcccctggtcaacttcaaagtgagcggcatc
aagtttctcaaggacaagctggtggaaatcggcgcacagaaagatgagctcagctttgaa
cagttccatctcttctataagaaactcatgtttgaccagcaaaaatcgatacttgacgaa
ttcaaaaaagactcctccgtgttcatcctaggaaacacagaccggccggatgcctcggct
gtctacctgcaggacttccaaaggtttcttttacatgaacagcaggagctatgggctcag
gatctgaacaaagtccgggagcggatgaccaagtttatcgacgacacaatgagagagacc
gcagagcccttcttatttgtggatgagttcctcacgtatctgttctcccgggagaacagc
atctgggacgagaagtacgatgcagtggacatgcaggacatgaacaaccccttgtcccac
tactggatctcctcttcccacaacacgtacctcactggggaccagctgcgtagtgagtcc
tccacggaagcgtatatccgctgtctgcgcgctggttgccgctgcattgagctggactgc
tgggacgggcctgatgggaagcccattatctaccacggctggacacggaccaccaagatc
aagtttgatgatgttgttcaggccatccgagaccacgcctttgttacctccagcttcccc
gtcatcttgtctatcgaggagcactgcagtgtggagcagcaacgtcacatggccaaggtg
ttcaaggaagtgttaggagacatgctgttgacgaagcccacagaggccagtgctgaccag
ctgccctcgcccagtcagcttcgtgagaagatcattatcaagcataagaagctgggtccc
aagggtgatgtcgacgtcaacgtggaggacaagaaagatgagcacaagccccagggcgag
ctgtatatgtgggactccatcgaccagaaatggacgcgccactactgtgccattgctgac
gccaagctgtccttcggtgatgacattgaacaggctgtggaggaggagccggtccaggac
actccccccacggagctgcattttggggagaaatggttccacaagaaggtggagagtagg
accagtgcggagaagctgctgcaagagtactgtgctgagaccggggccaaggacggcacc
ttcctggtgcgggagagcgagaccttccccaatgactacacactctccttctggcggtct
ggccgggtgcagcactgccggatccggtctactatggagaatggggtcatgaagtactac
ctgaccgacaacctcacgttcaacagcatctacgccctcatccagcactaccgtgaggca
cacctgcgctgcgcggagttcgagctgcggctcacagacccggtgcccaaccccaaccca
cacgagtccaagccgtggtactatgacagtctgagcaggggggaagcggaggacatgctg
atgcggatcccccgagatggagccttcctcatccggaagagggaggggaccaactcctac
gccatcaccttcagggccaggggcaaggtgaaacattgtcgcatcaaccgggacggacgc
cacttcgtgctgggcacctctgcctactttgagagcctagtggagcttgtcagctactac
gagaagcacgcgctctatcgcaagatgaggcttcgataccccgtgaccccggagctcctg
gagcgatataatatggaaagagacatcaactctctttatgacgtcagcaggatgtatgtg
gacccaagtgagatcaacccttccatgcctcagaggaccgtgaaagcgctctatgactac
aaagccaagcgcagcgacgagctgaccttctgccgcggtgccctcatccacaatgtctcc
aaggagcccgggggatggtggaaaggggactacgggacccggatccagcagtacttcccg
tccaactatgtcgaggatatctcggcaggcgatgctgaggagatggaaaagcagattatt
gaagacaatcccctcgggtctctctgcaaaggcatattggatcttaatacctacaacgtt
gtgaaggccccccaggggaaaaaccagaaagccttcgtctttatcctggagcctaagaaa
cagggagatcctcccgtggagttcgcgaccgaccgtgtggaggagctgtttgagtggttt
cagagcatacgggagatcacttggaagatggacaccaaggagaacaacatgaagtactgg
gagaggaaccagtccatcgccattgagctctcggacttggttgtatactgcaagccaact
agcaaaaccaaggaccatttggaaaatcccgacttccgagaaatccgctcttttgtggag
acgaaggcagacagcattgtcaggcaaaaacctgtcgatctattgcgatacaatcagaag
ggcctgacccgagtctaccccaagggacagagagttgactcttcgaactatgaccccttc
cgtctgtggctgtgcggctcccagatggtggcactcaatttccagactccagacaaatac
atgcagatgaaccacgcgctgttttcgctcaatgggcgaacaggctacgtcctgcagcct
gagagcatgcgctctgagaagtatgatccgatgcccctggagtcccagaggaagatcctg
atgacactcactgtcaaggttcttggtgcacgccacctccctaaactagggcggagtatt
gcctgtccttttgtggaggtggaaatctgcggggctgagtatgacagcaacaaattcaag
acgacggttgtgaatgacaatggcctcagccctgtctgggctccaactcaggagaaggtg
acatttgagatctatgatccaaaccttgccttcctacgctttgtggtctacgaagaagac
atgttcagtgatcccaacttcctggctcatgccacgtaccccattaaaggcatcaaatcc
gggtttagatcagtccctctgaagaatgggtacagtgaagacatcgagctggcatccctc
ctggttttctgtgagatgaggccagtcctggagagtgaagaggaactctattcctcctgt
cgccaactgcggaggcggcaagaagagctcaacaaccagctcttcctttacgacacgcac
cagaacctgcgcggagccaaccgtgatgccctggtgaaggagttcaatgttaacgagaat
cagctgcagctgtaccaggagaagtgcaaccggaggctgagagagaagagagtaagcaac
agcaggttctactcctag

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