KEGG   Mus musculus (mouse): 241226Help
Entry
241226            CDS       T01002                                 

Gene name
Itga8, AI447669
Definition
integrin alpha 8
Orthology
K06584  
integrin alpha 8
Organism
mmu  Mus musculus (mouse)
Pathway
PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Cell adhesion molecules (CAMs)
Regulation of actin cytoskeleton
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mmu00001]
 Environmental Information Processing
  Signal transduction
   04151 PI3K-Akt signaling pathway
    241226 (Itga8)
  Signaling molecules and interaction
   04512 ECM-receptor interaction
    241226 (Itga8)
   04514 Cell adhesion molecules (CAMs)
    241226 (Itga8)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    241226 (Itga8)
  Cellular commiunity
   04510 Focal adhesion
    241226 (Itga8)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    241226 (Itga8)
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    241226 (Itga8)
   05414 Dilated cardiomyopathy (DCM)
    241226 (Itga8)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
MGI: 
Ensembl: 
Vega: 
UniProt: 
Position
2 A1; 2 9.12 cM
AA seq 1062 aa AA seqDB search
MSAGTHCGPPGNRAPPFARLCCVSAALGMLWSPACLAFNLDVDKLTVYSGPEGSYFGYSL
DFYIPDARTASVLVGAPKANTSQPDIVEGGAVYYCPWPSERSAQCKQIPFDTTNNRKIRV
NGTKEPIEFKSNQWFGATVRAHKGKVVACAPLYHWRTLKPNPAKDPVGTCYVAIQNFSAY
AEHSPCRNSNADPEGQGYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITVSIADIIANYS
FKDILRKLAAEKQTDVAPASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQNFGYVSII
NSTDMTFIQNFTGEQMASYFGYTVVVSDVNNDGMDDILVGAPLFMEREFESNPREVGQVY
LYLQASALLFQDPQVLTGTETFGRFGSSVAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLI
YNGNPRGLHSKPSQVLQGIWGSQTIPSGFGFSLRGDADIDKNDYPDLLVGAFGKGKVAVY
RARPVVTVDAQLLLHPMIINLENKTCQIPEFPTPVACFSVRVCASIAGQSISNTIALLAE
VQLDFLKQKGAIKRTLFLHNHQSHFTFPFVMKQQKSLHCQDFMVYLRDETEFRDKLSPIN
ISLNYSLDDSTFKDSLEVKPILNHYRDNVVTEQAHILVDCGEDNLCVPDLKLSARPDKHQ
IIIGDENHLMLIINARNEGEGAYEAELFVIIPEEADYVGIERNNKGLRPLSCEYKMENVT
RMVVCDLGNPMVTGTNFSLGLRFAVPRLEKTNMSINFDLQIRSSNKDNPDSNFERVQINI
TAIAQVEIRGVSHPPQIVLPIHNWEPEKKPHKEEEVGPLVEHIYELHNIGPSTISDSILD
VGWPFSARDEFLLYIFHLQTLGPLQCQTNPEINPQDIKPAASPEDTPELSAFLRNATIPH
LVRKRDVPVVQLHRQSPARILNCTNIDCLQISCAVGRLGGGESAVLKVRSRLWAHTFLKR
KNDHYALASLVSFEVKKMPYKEQPAKLPAGSTAVKTSVIWATPNVSFSIPLWVIILAILL
GLLVLAILTLALWKCGFFDRARPPQDEMTDREQLTSDKTPEA
NT seq 3189 nt NT seq  +upstreamnt  +downstreamnt
atgtctgcgggaacccactgtggtcccccggggaaccgggcacctccgttcgcgcgtctc
tgttgcgtctcggccgcgctggggatgctgtggtcccctgcgtgtctggcgttcaacttg
gatgtggacaagctcactgtgtacagtggccccgagggcagctacttcggctactcactg
gacttctacatacctgatgcgcgcacagccagtgtcttagtgggggcacccaaagccaac
actagccagccggatatcgtagaagggggagctgtctactactgtccctggccctcagag
aggtctgcacagtgcaagcagataccgtttgacaccaccaacaacaggaaaatcagagtt
aatggaaccaaagaacctatagaatttaaatcaaaccagtggtttggagccacagtgaga
gctcacaaaggaaaagttgtggcttgtgcccctttgtatcactggagaactctgaaacct
aatccagcgaaggacccagttggcacatgctatgtagcaattcagaatttcagtgcctat
gctgagcactcaccttgtcgaaacagcaatgctgatcccgaaggccaaggttactgccag
gcagggtttagcctagacttctataagaatggagaccttatagtgggaggacctggaagt
ttttactggcaaggtcaggtgatcactgtcagtatagcagacatcattgcaaattactca
ttcaaggatattctacgaaaattggccgcagaaaagcagacagacgtggctccagcttcc
tatgatgacagctaccttggatattcggtcgctgctggagaattcactggggactctcag
caagaattggtggctgggattccaagaggagcacagaactttggatatgtctccatcatt
aactccacagacatgaccttcattcagaattttactggtgagcagatggcatcttatttc
ggatatactgttgtggtatcagatgttaacaatgatggcatggatgacatattggtcggg
gcacctctctttatggagcgagaatttgaaagtaaccctagagaagtgggacaggtctac
ttgtaccttcaagcaagcgccctcctcttccaagacccacaggtcctcaccggcacggag
acatttgggagatttggtagctctgtggcccacttgggggacctgaaccaagatggatac
aatgacatcgccatcggtgtgccctttgcaggcaaggatcaacgaggtaaagtcctcatt
tacaatggaaacccaagaggtttacacagcaagccttcccaagttctgcaaggaatatgg
gggtcacagaccatcccttctggatttggcttttctctaagaggagatgcagacatagac
aagaatgattacccagatttgcttgtaggggcatttggaaaagggaaagtagctgtttac
agagcaaggccagttgtaaccgtggatgcccagcttctgctgcacccgatgattatcaac
cttgaaaataaaacttgccagattccagaattccctactcctgtggcctgcttttctgta
agagtctgtgcatctatagcaggccagagcatttcaaatacaatagccctgctggccgag
gtgcagttagatttcctgaagcaaaaaggagccatcaaacggacgctctttctccacaac
caccagtcccatttcaccttcccctttgtgatgaagcagcagaaatccctccactgccag
gattttatggtttaccttcgggatgaaactgaattccgagataaattgtctccaatcaac
atcagcctgaactacagtttggatgattctacctttaaagacagcctggaagtgaagcca
attttgaaccactacagggacaatgtagttactgagcaggctcacatcctggtggactgt
ggagaagacaatctatgcgttcctgacttgaagctgtcagctagaccagataagcatcag
ataattattggcgatgaaaatcacctaatgctcataataaatgcaagaaatgagggagaa
ggggcctacgaagccgaactctttgttatcatccccgaagaagcagattatgttgggatt
gagcgcaacaacaagggactgaggcccctgagttgtgagtacaagatggaaaacgtgacc
aggatggtggtgtgtgaccttgggaacccgatggtgactggaacaaatttttctctgggc
ctccgatttgctgttcctcgccttgagaaaacaaatatgagcattaacttcgatctccaa
atcagaagctccaataaggacaatcctgacagcaacttcgagcgtgtacagatcaacatc
actgccattgctcaggtcgaaatcagaggagtgtcccaccctccgcagattgttctgccc
atccacaactgggaaccagaaaagaagccacacaaagaggaggaagtcggtcctttggtt
gagcatatttatgagctgcacaatattggacccagcaccatcagtgacagcattcttgac
gtgggctggccgttctctgcacgggatgagtttctcctctatatttttcatcttcaaact
ctgggacctctacaatgtcaaacaaatcctgagatcaacccacaggatataaagcctgct
gcctccccagaggatacccctgagctcagtgccttcttaagaaatgctacaattccccat
cttgtcagaaagagggatgtgccagtggtccagctccacagacagagccctgcaagaata
ctgaactgtaccaacattgactgcttgcaaatctcttgtgcagtgggtcgcctgggagga
ggcgaaagtgcagtcctaaaggtcagatcgagattgtgggcccacacgttcctcaagaga
aagaatgatcattatgctcttgcatccctggtgtcctttgaagtcaagaagatgccgtat
aaagaacagccagcaaagctgccagcggggagcacagcggttaagacgtcggttatttgg
gccactccgaatgtctccttctcaattccattgtgggtcataatactagcgatccttctt
ggtttgctggttctggctatcttaactttagctttatggaagtgtggattctttgataga
gcaagacctcctcaggatgaaatgacagacagggaacaactgaccagtgacaagacccca
gaggcgtga

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